Search Results

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Postdoctoral

Nationwide Children's offers postdoctoral opportunities for those individuals who recently received their degree in many of the Abigail Wexner Research Institute's research laboratories.

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Graduate Students

First-year graduate students are able to do short rotations though the Abigail Wexner Research Institute laboratories prior to committing to their thesis laboratories.

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Medical Students

Medical students may apply for research opportunities, with eight-week programs during their third year and four-week elective programs during their fourth year of medical school available.

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Awards and Fellowships

The Office of Trainee Affairs has several financial awards and fellowships that are aimed at supporting trainees throughout their research journey.

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Medical Fellows

Nationwide Children’s offers high-quality, nationally recognized fellowships in a wide range of pediatric subspecialties, most of which include opportunities in basic or clinical research. 

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Trainee Association

The Research Institute’s Trainee Association (RITA) was created in 2013 to help better train and prepare trainees for their “next steps.”

Kidney Disease Clinical Research

Learn more about clinical research relating to kidney disease.

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Gastroenterology, Hepatology & Nutrition Clinical Research

Learn more about clinical research relating to gastroenterology, hepatology & nutrition.

Clinical Research For Investigators

Clinical Research Services Clinical Research Services (CRS) is designed to be a portal through which clinical investigators access streamlined coordination of services necessary to initiate clinical research projects, regardless of funding source.

Gene Therapy Clinical Research

Learn more about ongoing clinical trials and other clinical research related to muscular dystrophies and other disorders.

Ear, Nose and Throat Clinical Research

Learn more about clinical research relating to ear, nose & throat services.

Emergency Services Clinical Research

Learn more about clinical research relating to emergency services.

Immunology Clinical Research

Learn more about clinical research relating to immunology.

Heart (Cardiology) Clinical Research

Learn more about clinical research relating to the heart.

Endocrinology Clinical Research

Learn more about clinical research relating to endocrinology.

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Cancer Clinical Research

Learn more about clinical research relating to cancer.

Ophthalmology Clinical Research

Learn more about clinical research relating to ophthalmology.

Orthopedics Clinical Research

Learn more about clinical research relating to orthopedics.

Sickle Cell Anemia Clinical Research

Learn more about clinical research relating to sickle cell anemia.

Pulmonary Medicine Clinical Research

Learn more about clinical research relating to pulmonary medicine.

Pediatric Trauma Clinical Research

Learn more about clinical research relating to pediatric trauma.

Rheumatology Clinical Research

Learn more about clinical research relating to rheumatology.

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Central Nervous System Tumors

A central nervous system (CNS) tumor begins when healthy cells in the brain or the spinal cord change and grow out of control, forming a mass, or tumor. If the tumor is malignant, it can spread to other parts of the body or brain, effecting a child’s thought processes and movements.

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Hematologic Disorders

Hematologic disorders are conditions found in the blood and blood forming organs. This includes blood cell cancers, genetic disorders, anemia, HIV related conditions, sickle cell disease, and complications do to chemotherapy treatment or transfusions.

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Leukemias and Lymphomas

Leukemia and lymphomas are some of the most common types of cancer in children, affecting one in three children who are diagnosed with pediatric cancer. These diseases are cancers of white blood cells and immune system, hindering the ability of the body to fight off infections.

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Other/Multiple Specialties

These trials involve finding solutions for patients who have more than one condition involving hematology, oncology, & bone and marrow transplant. Multispecialty studies focus on new ways to treat the whole patient through by studying the correlations between different diseases.

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Hematopoietic Stem Cell Transplant

Hematopoietic stem cells in the blood that may have many other applications to treat more than just cancers of the blood. Our team uses hematopoietic stem cell transplant clinical trials to find faster and more personalized tactics solutions for multiple different kinds of cancers throughout the

Investigator-Initiated Cancer Clinical Studies

Learn more about investigator-initiated trials.

Neuro-Oncology Clinical Research

Learn more about clinical research relating to pediatric brain and spinal cord tumors.

Germ Cell Cancer Clinical Research

Learn more about clinical research relating to germ cell tumors.

Sarcoma and Solid Tumor Studies

Learn more about clinical research relating to sarcomas and solid tumors.

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Grant Funding

Our team collaborates with researchers and clinicians to identify funding opportunities, develop grant proposals, and carry out project tasks for funded projects.

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Extended Reality

At Nationwide Children’s, extended reality is used to develop innovative digital health solutions that enhance patient care. The team crafts engaging and impactful products to elevate the quality of care we deliver.

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Publications and Presentations

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Finance and Sponsored Projects

The Finance and Sponsored Project Department supports grant and contract funding from the start of a search for funding through the closeout of a project. We know it takes teamwork for a successful project and are prepared to assure our researcher's time is spent focused on the science of research and not administrative details.

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Media

Mohana Ravindranath, “Can voice tech limit COVID spread?” [Interview]. Politico, Morning eHealth Newsletter. 11/30/2020. (Open access copy) Darius Tahir & Mohana Ravindranath, “What Siri and Alexa can do for COVID?” [Quote].

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Resources For Investigators

Learn more about the intramural funding program, research release time and investigational drug service.

22q Deletion Syndrome Clinical Research

Learn more about clinical research relating to 22q deletion syndrome.

Adolescent Health Clinical Research

Learn more about clinical research relating to adolescent medicine.

Clinical Research Blog Library

The 700 Children's blog covers the most common topics, frequently asked questions and current pediatric health care information written by pediatric experts. Our team covers the latest from clinical study participation and beyond.

Speech and Language Pathology Clinical Research

Learn more about clinical research relating to speech and language pathology.

Safety and Injury Prevention Clinical Research

Learn more about clinical research relating to safety and injury prevention.

Pediatric Surgery Clinical Research

Learn more about clinical research relating to surgery.

Cell Therapy Clinical Research

Find and explore clinical studies at Nationwide Children's Hospital that focus on cell therapy.

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Davenport Lab

The Sleep Empowers Lab, led by Mattina Davenport, PhD, focuses on improving community sleep health through community-driven research and initiatives to improve sleep health equity by empowering populations.

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Chavez Lab

The Chavez Lab, led by Laura Chavez, PhD, MPH, seeks to address population behavioral health equity and improve understanding of the social drivers of outcomes for youth.

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CHTN Pediatric Division

The Cooperative Human Tissue Network (CHTN) facilitates access to human tissue for research, accelerating scientific discoveries in medical diagnoses and treatment. The Pediatric Division is managed by the Biopathology Center at Nationwide Children’s Hospital.

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About Us

The BCR at Nationwide Children's Hospital is composed of six primary workgroups: Client Services Logistics Histology Pathology and Virtual Microscopy Molecular Informatics This subdivision of workgroups creates a modular system which allows the BCR flexibility and variety in the functions it

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ALCHEMIST

The Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trials, or ALCHEMIST, is a group of clinical trials for patients with certain types of early-stage non-small cell lung cancers (NSCLC) that have been treated surgically.

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Exceptional Responders

The National Cancer Institute (NCI) has embarked on the Exceptional Responders (ER) Initiative to understand the molecular underpinnings of exceptional responses to treatment, primarily via chemotherapy, in cancer patients.

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BCR Training Resources

TSS Training Webinar: Click here to download the training webinar. OpenClinica Training Manual: Click here to download the training manual. FFPE Scroll Calculuator: Click here to download the FFPE scroll calculator.

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Burkitt Lymphoma Genome Sequencing Project

The BCR serves as the biospecimen processing core for the Burkitt Lymphoma Genome Sequencing Project (BLGSP). Burkitt lymphoma is a type of non-Hodgkin lymphoma that occurs most often in children and young adults.

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Clinical Trials Sequencing Project

The Clinical Trials Sequencing Project (CTSP) will promote the use of genomics to explain the molecular basis of response and resistance to therapies studied in National Cancer Institute (NCI)-sponsored clinical trials of the National Clinical Trials Network (NCTN).

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Cancer Driver Discovery Project

The Cancer Driver Discovery Project (CDDP) aims to identify driver mutations that occur in two percent or more of cancer cases. Further explanation of the molecular causes of cancer through deeper characterization of tumors is expected to yield insights into tumor biology, leading to better

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Contact Us

Biospecimen Core Resource The Abigail Wexner Research Institute at Nationwide Children's Hospital 700 Children's Drive Columbus, Ohio 43205 Main Phone: (614) 355-2919 Key Contacts at the BCR Jay Bowen Principal Investigator Sara Coppens Project Manager Hilary Petrello Client Services Kevin Bennett

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Announcements

See the latest announcements about the Center for Injury Research and Policy including information about recent awards, publications, studies, and events.

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TCGA Forms and Documents

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Translational Research Team

Tracy Mehan, MA Director of Research Translation and Communication Tracy leads the Translational Research team for the Center for Injury Research and Policy bringing close to 30 years of experience in communications, health education, marketing, and research to her role.

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Henry Xiang Team

Henry Xiang, MD, MPH, PhD, MBA Principal Investigator Dr. Henry Xiang is a Professor of Medicine and Epidemiology at The Ohio State University. He is the founding Director of the Center for Pediatric Trauma Research as well as the Research Director at Center for Injury Research and Policy. Dr.

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HIV+ Tumor Molecular Characterization Project

The HIV+ Tumor Molecular Characterization Project (HTMCP) will study 100 cases each of diffuse large B-cell lymphoma, lung cancer, and cervical cancer.

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The Cancer Genome Atlas

The Biospecimen Core Resource (BCR) at Nationwide Children’s Hospital served as the centralized tissue processing and clinical data collection center for The Cancer Genome Atlas (TCGA) from 2009-2015.

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Injury Control Research Center Designation

CIRP was a CDC-funded Injury Control Research Center for 16 years until 2024, and the only one that focused on injuries to children and adolescents.

Media Center

See the latest news coming out of the Center for Injury Research and Policy including press releases, announcements about recent awards, publications, studies, and events, as well as upcoming media trainings.

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OpenClinica Training Manual

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Ginger Yang Team

Jingzhen Ginger Yang, PhD, MPH Principal Investigator Dr. Jingzhen (Ginger) Yang is a Principal Investigator at the Center for Injury Research and Policy, of the Abigail Wexner Research Institute at Nationwide Children’s Hospital.

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Education and Training

CIRP’s educational and training programs generate global interest in injury prevention and train the future leaders in the field.

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Gary Smith Team

Gary A. Smith, MD, DrPH Principal Investigator Dr. Gary A. Smith is a professor of Pediatrics, Emergency Medicine and Epidemiology at The Ohio State University.

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TCGA Publications

2016 Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. doi:10.1016/j.cell.2015.12.028 Read the full article 2015 The Molecular Taxonomy of Primary Prostate Cancer. Cell.

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Health Communication Internship

Ever heard of Translational Research? It’s where we take research out of the academic journals and get it into the community. At the Center for Injury Research and Policy at Nationwide Children’s Hospital, the Translational Research Team focuses on preventing the leading cause of death

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Trainees for Child Injury Prevention

What is Trainees for Child Injury Prevention (T4CIP)? T4CIP is a year-long training program for medical students, residents, and fellows. During monthly virtual sessions, national experts deliver lessons on child injury prevention and advocacy.

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Research Grants

See the latest grants awarded to the researchers at the Center for Injury Research and Policy.

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ICRC Research Projects 2019-2024

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ICRC Research Projects 2012-2019

Drug Overdoses and Poisonings among Adolescents and Young Adults in Ohio Principal Investigator: Xiang Findings will provide statistical data about drug poisonings among adolescents and young adults in Ohio, which will be used to guide intervention programs to prevent drug overdoses and poisonings

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Exploratory Research Project Grant Program

The Center for Injury Research and Policy (CIRP) in the Abigail Wexner Research Institute at Nationwide Children's Hospital releases this request for applications for its Exploratory Research Project Grant Program.

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Making an Impact

From design changes in consumer products to new public policy, CIRP's influence is leading the way to a safer world at the local, national and global levels.

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ICRC Research Projects 2008-2011

Childhood Injury Statistics Using the National Electronic Injury Surveillance System (NEISS) (Principal Investigator: Xiang) Findings will aid in developing and evaluating methods of using point-of-care clinical information systems to report injuries and other acute health problems to public health

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Julie Leonard Team

Julie Leonard, MD, MPH Principal Investigator Julie Leonard, MD, MPH, is a Professor of Pediatrics at Nationwide Children's Hospital and the Ohio State University College of Medicine.

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Lara McKenzie Team

Lara McKenzie, PhD, MA, FAAHB Principal Investigator Lara B. McKenzie, PhD, MA, FAAHB, is a principal investigator in the Center for Injury Research and Policy at the Abigail Wexner Research Institute at Nationwide Children's Hospital and an associate professor in the Department of Pediatrics,

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International Faculty

The Center for Injury Research and Policy (CIRP) of the Abigail Wexner Research Institute at Nationwide Children’s Hospital has invited selected scientists outside the United States whose work is primarily concerned with injury control and prevention to become international affiliate faculty.

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Grant Archives

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Student Awards

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Child Road Safety in the Americas

San Jose, Costa Rica May 7-8, 2015 During United Nations Global Road Safety Week The Child Road Safety in the Americas Congress, taking place on May 7-8, 2015, during UN Global Road Safety Week, addresses the important public health and sustainable development issue of child road safety in the

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Media Trainings

Let the media experts at the Center for Injury Research and Policy at Nationwide Children’s Hospital show you how to work with the media, make your message newsworthy and attractive to a media outlet, connect with your audience, and create an outreach and evaluation plan.

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The Ohio State University Courses

The principal investigators at the Center for Injury Research and Policy also have joint appointments as faculty members at The Ohio State University Colleges of Medicine and Public Health.

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E-cigarettes and Liquid Nicotine

Just a small amount of liquid nicotine can be deadly to a child. Poisoning can happen in two ways: when the liquid is swallowed or when it is absorbed through the skin.

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Marijuana Edibles

A marijuana edible, cannabis edible, or simply “edible” is any food or beverage that contains THC, the psychoactive ingredient in marijuana, or cannabidiol (CBD). THC or CBD have been added to all sorts of foods, such as chips and candies, and even drinks.

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Safe Play on Farms

Although farms are places for work, more than 1 million children live on farms, and many more visit farms every year.

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Exertional Heat-Related Injuries

Unlike classic heat-related injuries, exertional heat-related injuries do not require extremely high ambient temperatures to cause harm.

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Crutches, Walkers & Wheelchairs (Mobility Aids)

Children and teens with an injury or disability may need to use mobility aids, such as crutches, walkers and wheelchairs, to help them get around more easily.

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Sun Safety

While enjoying the summer weather can mean going outdoors and getting active, it is important to keep in mind that exposure to the sun and heat can lead to serious injuries.

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Traumatic Brain Injury

Every year, there are approximately 12,500 deaths related to pediatric traumatic brain injury (PTBI) for children and young adults ages 25 years and younger in the United States.

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Student Publications

All of the following publications had a student as either the lead author or as a co-author. Students' names are in bold in the citation.

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Batteries

There are two types of batteries. One kind is long and skinny like AA or C. Many flashlights and toys use that kind. The other kind of battery is round, flat, and looks like a silver button. Button batteries are in watches, key fobs, thermometers, singing cards, and many other items in your home.

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Back-to-School Safety

When summer comes to an end, children get ready to go back to school. This is a great time for parents to talk to their kids about how to safely travel to and from school.

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International Training Program

According to the World Health Organization: Each year, there are over 800,000 injury-related deaths globally among children younger than 18 years of age Tens of millions of children require hospital care due to injuries annually 90% of the world's pediatric deaths from injuries occur in low- and

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Amputations

Many pediatric amputations are door-related. Doors are easily accessible to the exploring fingers of young children who are unaware of the potential dangers.

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Pet Medication Risks for Children

Almost two thirds of households in the US own a pet and many of these households have children. Many parents may not be aware of the risks these medications can pose to their families.

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RIO™

RIO™ is an internet-based surveillance software developed by Dr. Comstock. This powerful yet flexible surveillance software has been the centerpiece of Dr. Comstock’s research.

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ReACT Study

Concussion among youth is a major public health issue today. While too little rest can aggravate symptoms and slow recovery, too much rest is impractical. 

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Secondary Injuries Among Individuals with Disabilities

Currently, 40 to 50 million people in the United States live with various disabilities and this number is expected to increase substantially in the coming years.

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Thakkar Lab

Under the direction of Rajan Thakkar, MD, the Thakkar lab’s research aims to examine immune function at the systemic and tissue level in pediatric thermal injury using both whole blood and tissue specimens.

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Bradbury Lab

The Bradbury Laboratory is dedicated to understanding disease mechanisms and developing therapeutic approaches for rare, pediatric neurodegenerative disorders.

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Annual Myology Training Course

The Myology Course at Nationwide Children's is the only U.S. workshop of its kind, featuring a mix of basic and clinical science lectures followed by specific training in either clinical treatment protocols or basic science laboratory techniques.

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OSU and Nationwide Children's Muscle Group

The OSU and Nationwide Children's Muscle Group brings together investigators with diverse research interests in skeletal muscle, cardiac muscle, and neuromuscular biology.

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What's New in Muscular Dystrophy?

Join Kevin Flanigan, MD, and his guests for What’s New in Muscular Dystrophy?, a webinar series that highlights the latest in basic and clinical research at Nationwide Children's Hospital. 

"This Month in Muscular Dystrophy"

Hosted by Kevin Flanigan, MD, "This Month in Muscular Dystrophy" podcasts highlight the latest in muscular dystrophy and other inherited neuromuscular disease research.

Meet Our Team

Learn more about director Kevin Flanigan, MD, and the team of principal investigators at the Jerry R. Mendell Center for Gene Therapy.

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Saad Lab

Under the direction of Nizar Saad, MSc, PhD, the Saad Lab conducts cutting-edge research to understand the causes of genetic disorders, including neuromuscular diseases, and develops innovative techniques to diagnose, treat and cure these conditions.

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Kerlin Lab

Under the direction of Bryce Kerlin, MD, the Kerlin Lab aims to discover new approaches to prevent and treat thrombosis.

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Grayson Lab

Under the direction of Mitchell Grayson, MD, the Grayson Lab studies how allergic diseases, like food allergy and asthma, develop, how respiratory viral infections can drive that development and how allergic disease affects the antiviral immune response in the lung.

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Sribnick Lab

Under the direction of Eric A. Sribnick, MD, PhD, the Sribnick Lab's research focuses on how the body’s immune system responds after traumatic brain injury.

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Bonny Lab

Under the direction of Andrea E. Bonny, MD, the Bonny Lab focuses on research to inform clinical practice for adolescents at peak risk for nonmedical use of prescription opioids, as well as dictating public policy. In the same manner, the Bonny Lab seeks to inform clinical practice for AYA on contraception.

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Chang Lab

Learn more about Long-Sheng Chang, PhD, and the staff in the Chang Lab.

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Roberts Lab

The Roberts Lab focuses on understanding the interactions that occur between cancer cells and the "normal" tissues that surround them.

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Rashnonejad Lab

Under the direction of Afrooz Rashnonejad, MSc, PhD, the Rashnonejad Lab focuses on developing adeno-associated virus (AAV)-based gene therapies for neuromuscular and neurodegenerative diseases.

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Martin Lab

Under the direction of Paul Martin, PhD, the Martin Lab's goal is to develop curative therapies for children with neuromuscular and lysosomal disorders, including forms of muscular dystrophy, lysosomal storage disorders, myopathies and motor neuron diseases.

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Nicolau Lab

Under the direction of Stefan Nicolau, MD, the Nicolau Lab aims to further the translational development of gene editing therapies for muscle disorders, with a particular emphasis on genetic mutations that require insertion of hundreds or thousands of base pairs into genomic DNA.

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Magaña Lab

The Magaña Lab bridges the clinic and the laboratory by utilizing a multidisciplinary and innovative approach to advancing the field of pediatric neuroimmunology. Dr. Magaña’s clinical and research focus is on studying the age-span of multiple sclerosis—fetal and neonatal neurology, as well as childhood, adolescent and adult neurology.

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Gene Therapy and Neuromuscular Training

Nationwide Children’s Hospital is not only home to world-class neuromuscular research and clinical services, it’s also the hub of an extraordinary and collaborative training environment.

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Rasmussen Lab

The Rasmussen Lab is dedicated to investigating the role that Human Endogenous Retrovirus K (HERV-K) has in the cellular transcriptome of pediatric tumors. HERVs are ubiquitous genetic elements, resulting from ancient retroviral infections of the human genome.

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Gene Therapy Research and Projects

Learn more about muscular dystrophy research and other areas of focus at the Jerry R. Mendell Center for Gene Therapy and see the latest featured research and projects to come out of our center.

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Smoyer Lab

Under the direction of William E. Smoyer, MD, the Smoyer Lab focuses its research around three main themes of nephrotic syndrome, one of the most common kidney diseases seen in children.

Meet Our Team

Learn more about director William Smoyer, MD, and his team of principal investigators at the Center for Clinical and Translational Research.

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Chandler Lab

Under the direction of Dawn Chandler, PhD, the Chandler Lab focuses on the regulation of pre-mRNA splicing and its disruption leading to pediatric cancer and spinal muscular atrophy.

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Stanton Lab

Under the direction of Benjamin Stanton, PhD, the Systems Epigenetics Group is a highly collaborative group, focusing on pediatric cancer epigenetics and genomics.

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Cassady Lab

Learn more about Kevin Cassady, MD, and the lab staff in the Cassady Lab.

Meet Our Team

Learn more about the team of principal investigators at the Center for Childhood Cancer Research.

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Drissi Lab

Under the direction of Rachid Drissi, PhD, the Drissi Lab investigates the molecular pathways driving the differentiation and proliferation of high-grade pediatric brain tumors to identify and develop targeted therapies with the greatest potential impact for patients and their families.

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Kendall Lab

Under the direction of Genevieve Kendall, PhD, the Kendall Lab focuses on developing basic and translational models of pediatric sarcomas—devastating and aggressive solid tumors with limited therapeutic options. The lab's goal is to apply the models as discovery- based tools to derive mechanistic insights for improving outcomes for children with cancer.

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Brigstock Lab

Under the direction of David R. Brigstock, PhD, the Brigstock Lab’s primary focus is on fibrosis, a pathological process in which excessively large amounts of collagenous scar material are deposited between cells of major organs and tissues.

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Wang Lab

Under the direction of Ruoning Wang, PhD, the Wang Lab conducts research to understand the fundamental questions related to cell metabolism, cell cycle, and cell fate determination in various physio-pathological contexts.

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Germain Accelerator Program

Accelerator programs at Nationwide Children’s Hospital transform patient care, improve health equity and access to care and benefit the community.

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Martin Lab Staff

Learn more about principal investigator Paul Martin, PhD, and his dynamic team in the Martin Lab.

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Theisen Lab

Under the direction of Emily Theisen, PhD, the Theisen Lab aims to increase the clinical impact of epigenetic targeted therapies for children with cancer.

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Peds-ONC Immunotherapy Center

The Pediatric Ohio-New York Cancer (Peds-ONC) Immunotherapy Center’s overarching hypothesis is that, in addition to adaptive immunotherapies, innate immune mechanisms of resistance in pediatric cancers can be leveraged as cancer immunotherapeutics.

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OTC Events

Learn more about our available technologies and commercialization success stories at our technology showcase events.

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Midwest Pediatric Device Consortium

A new consortium led by Nationwide Children’s Hospital and The Ohio State University – the first of its kind in the Midwest – will develop, produce and commercialize pediatric medical devices.

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September 2012

Professor Francesco Muntoni discusses congenital muscular dystrophies.

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June 2013

Dr. Paul Martin discusses Galgt2 gene therapy for muscular dystrophy.

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December 2012

Dr. Federica Montanaro discusses new cardiac dystrophin associated proteins.

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January 2015

Dr. Louise Rodino-Klapac discusses dysferlin overlap vectors to restore function in dysferlinopathies.

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July 2011

Dr. Carsten Bonnemann discusses collagen VI myopathies and a novel cause of ullrich congenital muscular dystrophy.

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October 2010

Dr. Annemieke Aartsma-Rus discusses progress in antisense oligonucleotide therapies.

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April 2010

Gene transfer of follistatin: Dr. Mendell discusses implications for muscle disease.

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January 2011

Dr. Jerry Mendell discusses dystrophin immunity in duchenne muscular dystrophy.

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July 2013

Dr. Jeff Chamberlain discusses gene and cell mediated therapies for muscular dystrophy.

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April 2012

Dr. Jerry Mendell discusses newborn screening in duchenne muscular dystrophy.

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December 2011

Dr. Denis Guttridge discusses NF-kB therapy for duchenne muscular dystrophy.

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December 2010

Dr. Craig McDonald discusses the six-minute walk test as an outcome measure in DMD.

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March 2015

Dr. Jerry Mendell discusses phase 1/2a follistatin gene therapy trial for becker muscular dystrophy. 

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May 2010

Dr. Brian Kaspar discusses gene transfer in spinal muscular atrophy (SMA).

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June 2010

Professor Kate Bushby discusses cinical care standards in muscular dystrophy.

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February 2011

Dr. Scott Harper discusses DUX4 as a potential candidate gene for facioscapulohumeral muscular dystrophy.

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February 2015

Dr. Kevin Flanigan discusses IRES-Induced Dystrophin as a potential therapy for DMD.

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July 2012

Dr. Louise Rodino-Klapac discusses advances in dysferlin gene therapy.

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August 2011

Dr. Valérie Allamand discusses the function of Selenoprotein N in muscle and its link to neuromuscular disorders.

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January 2012

Dr. Steve Wilton discusses antisense-induced exon skipping.

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Past Events

Past research events for faculty and staff.

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DISCOVERYx 2016

DISCOVERYx 2016 is a TEDx-inspired event that showcased ten presenters sharing their "story behind discovery” here at Nationwide Children’s. Last year's event was held on June 15, 2016.

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Institutional Review Board

The Institutional Review Board (IRB) reviews and provides oversight of all research involving human subjects at Nationwide Children's Hospital and its affiliated institutions. The IRB has the authority to approve, require modifications in, or disapprove all research activities that fall within its jurisdiction.

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2025 Meeting Dates

Learn more about the Institutional Review Board (IRB) Full Committees’ meeting dates and the dates by which the items for the full IRB agenda are due in the IRB office.

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Our Services

Consulting Our team currently provides regulatory affairs support and consulting for numerous academic, private, and publically traded programs working towards clinical development of AAV-based gene and cell-based therapies.

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GMP Facility

The cGMP Clinical Manufacturing Facility is located at Andelyn Biosciences, an affiliate company of Nationwide Children's Hospital.

DISCOVERYx 2019

DISCOVERYx 2019 was held live on June 11, 2019. Thank you to everyone who attended and celebrated discoveries that make a difference to improve pediatric health.

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Federal Wide Assurance Information

Assurance #: FWA00002860 Registration #: IRB00000568 Institution #: IORG0000326

DISCOVERYx 2021

The fifth annual DISCOVERYx program was showcased virtually on June 23 and June 30, with three presentations shown each day. Following each talk, speakers answered attendees questions during live Q&A sessions.

DISCOVERYx 2018

DISCOVERYx 2018 is a TEDx-inspired event that showcases presenters sharing “their story behind discovery” at Nationwide Children’s Hospital.

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National Health IT Week

For the second time, Nationwide Children's Hospital celebrated National Health IT Week to show how Information Technology employees are helping transform healthcare at Nationwide Children's Hospital.

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Biostatistics Resource at Nationwide Children's Hospital (BRANCH)

The Biostatistics Resource at Nationwide Children's Hospital (BRANCH) is an extension of The Ohio State University's Center for Biostatistics. BRANCH provides collaboration and assistance for grant development, data analysis, publication-ready results and statistical education.

Multimedia

Barry Halpern: Addicted to Love: Rethinking Care for Babies Born to Opiate-Dependent Mothers

Multimedia

Lorraine Kelley-Quon: Hold Your Baby: Transforming Infant Health with Kangaroo Care

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Erin Tebben: Kicked Out of Preschool: How Early Childhood Expulsions Affect Families

Multimedia

Michael Patrick: Maximum Impact: Engaging Families and Colleagues with Digital Content

Multimedia

Laura Gran: Connecting and Communicating: Unwrapping Life's Greatest Gifts

Multimedia

Jeremy Patterson: Seeking Out Tomatoes for Exemplary Outcomes

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John Mahan: Physicians Growing & Flourishing in Medicine

Multimedia

David Stukus: Twitter Has Made Me a Better Doctor

Multimedia

Tim Cripe: Bluffing Cancer

Multimedia

Deena Chisholm: Alchemy for Health Equity

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Policies and Procedures

Institutional Review Board (IRB) at Nationwide Children's Hospital Standard Operating Procedure (SOP) Documents HRP-001 - Definitions HRP-012 - Observation of Consent Process HRP-013 - LARs, Children, and Guardians HRP-020 - Incoming Items HRP-021 - Pre-Review HRP-022 - Humanitarian-Use-Devices

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Our Team

Kevin Bosse, PhD, RAC-US, CABP(H) Director Kevin Bosse, PhD, RAC-US, CABP(H), joined the Office of Research Regulatory Affairs (ORRA) in 2017. As a RAC-certified regulatory professional, he advises the development and regulatory strategy of novel drugs, biologics and devices under the Cellular

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Regulations and Guidance

OHRP Office for Human Research Protections Considerations and Recommendations Concerning Internet Research and Human Subjects Research Regulations, with Revisions (SACHRP) FAQs, Terms and Recommendations on Informed Consent and Research Use of Biospecimens (SACHRP) Human Subjects Regulations

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Our Innovation

Growing our own Cardiac Vessels Most doctors use plastic grafts to replace damaged arteries and blood vessels in children’s hearts. The problem is that organic hearts grow over time and synthetic plastics do not. To solve this, Dr. Christopher Breuer and Dr.

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Computational Resources

Advances in biomedical science place extreme demands on investigators for computational technology. We are working to meet those demands with a comprehensive array of computational services including biostatistics, epidemiologic analysis, database design and technical support.

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High Performance Computing

About Us The High Performance Computing (HPC) group opened in July 2015, and operates the Baker compute cluster, named for Dr. Sarah Josephine Baker. High Performance Computing supports researchers by providing computational resources for analysis and simulation of datasets ranging in size from

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Our Mission and Strategic Plan

The Abigail Wexner Research Institute at Nationwide Children's Hospital is dedicated to enhancing the health of children by engaging in high-quality, cutting-edge research according to the highest scientific and ethical standards.

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Microscopy Core

The Microscopy Core provides training, consultation and advanced support for optical microscopy and image analysis to investigators throughout Nationwide Children’s Hospital.

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Joanne Turner

Joanne Turner, PhD, is the chief scientific officer and the interim director of the Center for Microbe and Immunity Research at the Abigail Wexner Research Institute at Nationwide Children's Hospital. She is also an Elizabeth M. and Richard M. Ross Endowed Chair in Pediatric Research. Dr. Turner’s research focuses on immunity to mycobacterial infection in relation to aging.

Research Employee Access

The following links are ONLY for current employees:

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Induced Pluripotent Stem Cells Core

The goal of the iPSC Core is to generate and share iPSC lines with investigators not only at Nationwide Children's and The Ohio State University, but throughout Ohio and across the country.

Article

Animal Resources Core

The Animal Resources Core (ARC) assists with animal health and study support, animal acquisition and transport, training and husbandry and housing. The Abigail Wexner Research Institute is committed to ensuring the humane care of the animals utilized for research and teaching. The ARC balances compassionate animal care with research needs to deliver the highest quality service and discovery in pediatric research.

Article

Featured News and Research

Stay up to date with the latest news releases and features coming out of the Center for Child Health Equity and Outcomes Research.

Article

Endowed Chairs

Endowed chairs at Nationwide Children's Hospital represent the most prestigious and significant recognition of a scientist's or clinician's work.

Meet Our Team

Learn more about director Deena Chisolm, PhD, and her team of principal investigators at the Center for Child Health Equity and Outcomes Research.

Article

Creary Lab

The Creary Lab, led by Susan Creary, MD, MSc, focuses on improving outcomes of children, adolescents and young adults with sickle cell disease (SCD).

Article

Data Science

Our Data Science team employs innovative approaches for acquiring, managing, retrieving, and analyzing data.

Article

Design and Technology

We focus on user-centric design to develop holistic strategies for the specific needs of your custom web or mobile application/device.

Design and Technology Case Studies

Article

Data Collaboration

We offer services including Data Management, Data Warehousing, Honest Broker, Reporting Services, Electronic Data Capture, and Big Data.

Article

QREK

Considering more than 70% of healthcare information is stored in unstructured clinical notes, healthcare providers increasingly demand effective text-search systems for clinical care, QI reporting and research projects.

Article

Innovation and Technology

The Research Institute at Nationwide Children’s Hospital is dedicated to developing promising new technologies to advance the practice of pediatric health care. 

DISCOVERYx: The Stories Behind Discovery

Learn more about research and academic events going on at Nationwide Children's Hospital.

Article

The Office of Research Regulatory Affairs (ORRA)

Moving discoveries from bench to the best outcomes for children everywhere. The Abigail Wexner Research Institute at Nationwide Children’s Hospital enhances the health of children by engaging in high quality, cutting-edge research that results in better ways to prevent, screen for, diagnose

About Us

If you have projects that would benefit from IT Research and Innovation services, we’d love to collaborate with you to understand your problem, evaluate possible approaches, and co-design an optimal solution.

Article

Meet Our Extended Reality Team

Discover the team driving extended reality innovations at Nationwide Children's Hospital.

DISCOVERYx 2017

DISCOVERYx is a TEDx-inspired event that showcases ten presenters sharing their “story behind discovery” here at Nationwide Children’s. This year's events was held on June 23, 2017.

Article

Integrated Care for Kids

The Integrated Care for Kids (InCK) project is a child-centered service delivery and payment innovation model that aims to improve the quality of care and reduce expenditures with a focus on children under 21 years of age covered by Medicaid through prevention, early intervention, and treatment of behavioral and physical health needs.

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News Archive

$13.1 Million Innovation Grant Expands Pediatric Health Care for Underserved Children The State of Ohio, Partners for Kids, Nationwide Children’s Hospital and Akron Children’s Hospital unite to expand innovative model of health care delivery for underserved children (June 18, 2012).

Article

Center for Cancer Genomics at the National Cancer Institute (NCI CCG) Project Team

The BCR is a laboratory and biorepository within the Biopathology Center (BPC) that supports multiple cancer genomics projects for the Center for Cancer Genomics (CCG) at the National Cancer Institute (NCI) and other contracted entities.

Article

BB and Paintball Guns

Nonpowder firearms have long been marketed to children and teenagers as toys or “starter” firearms and include BB, pellet, airsoft, and paintball guns.

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Inflatable Bouncer Safety

Inflatable bouncers can be a source of fun and entertainment for children. However, they can also lead to serious injuries, such as broken bones and concussions. 

Article

Motor Vehicle Crashes

Motor vehicle crashes are one of the leading causes of injuries among adults and children in the United States. Every 15 minutes in the U.S. one person is killed and 66 are treated in an ER.

Article

Cheerleading Safety

Many cheerleaders are injured while practicing and performing each year in the US. With proper training, rules and spotting, however, many of these injuries can be prevented.

Article

Motorcycle Injuries

Motorcycle-related fatalities and fatality rates have been increasing rapidly during the past decade in the US. Researchers recommend wearing helmets to reduce both fatal and non-fatal injuries.

Article

All Terrain Vehicles (ATVs)

Given the rapidly increasing injury rates affecting children under 16 years of age, researchers recommend taking actions to help prevent injuries and deaths related to the use of ATVs.

Article

Playground Safety Children Younger Than 6 Years

More than 213,000 children are treated in emergency departments in the U.S. for playground-related injuries each year.

Article

Soccer

Soccer is more popular in the United States than ever before and it is a great way to get kids outside and staying active. However, as with any sport, there is a risk of injury.

Article

Window Blinds

Young children are quick, curious, and unable to recognize danger. Many parents underestimate these factors. There is a misperception that if we just watch our kids carefully, they will be safe. But even the best parent in the world cannot watch their child every second of every day.

Article

Football Injuries

Football safety equipment should include a helmet with a NOCSAE seal, mouth guards, shoulder pads, football pants with pads, and football shoes with cleats.

Article

Program Resources

CIRP was established in 1999 and became the first center of emphasis in The Abigail Wexner Research Institute at Nationwide Children's Hospital. It was a CDC-funded Injury Control Research Center for 16 years until 2024, and the only one that focused on injuries to children and adolescents.

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Lacrosse Safety

Like many school sports, lacrosse is a good way to stay active and have fun. Coaches, officials, athletic trainers, parents, and players can all help keep athletes safe.

Article

High School RIO™

High School RIO™ is the internet-based data collection tool used in the National High School Sports-Related Injury Surveillance Study. This study was first implemented during the 2005/06 academic year and has been maintained annually.

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RIO™ Publications

The following is a list of peer-review scientific manuscripts based on data from the National High School Sports Injury Surveillance System for the 2005-06, 2006-07 and 2007-08 academic years data. Kerr ZY, Casa DJ, Marshall SW, and Comstock RD.

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Winter Sports

Winter can be a time of great fun. However, these activities can lead to injuries. Following a few safety tips can help you and your family have a fun and safe winter.

Article

Gymnastics

Although gymnastics is a popular sport in the US, it continues to be overlooked in terms of potential for injury while having one of the highest injury rates of all girls’ sports.

Article

Amusement Ride-Related Injuries Infographic

From May to September each year, an average of 20 children per day are treated for amusement ride injuries across the US.

Article

Weight Training

People of all ages enjoy weight training as a way to get and stay in shape. Unfortunately, as the popularity of the activity has increased, so has the number of injuries. 

Article

Basketball Injuries

Basketball is a popular youth sport in the United States. The large participation numbers, though, mean that thousands of children are injured in practices and games every year. 

Article

Sports Injury

Sports-related injuries are common in the US among adolescents. If your child participates in any of these sports, be sure to take the proper precautions. 

Article

Concussions

A concussion is a type of traumatic brain injury. It is caused by a blow to the head or to the body that puts large forces on the brain. Common causes of concussions include car or ATV crashes, falls (especially from playground equipment or bikes), and sports-related collisions (with other athletes, the ball, the ground, or equipment). 

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Horse-Related Injuries

Caring for and riding horses are popular activities in the U.S., but both can lead to injuries. Horse-related injuries can be particularly severe and often require treatment in emergency departments.

Article

Summer Camp

About 11 million children and young adults attend summer camp each year. While there are many advantages to spending time at summer camp, there is, as always, the possibility of injury.

Article

Water Beads

Water beads can be appealing to children and adults because they’re colorful and look fun. But they can be dangerous around young children and people with developmental delays.

Article

Laundry Detergent Packets

Laundry detergent packets are small packets of detergent that can be tossed straight into a washing machine. They are a quick way to use the right amount of detergent without measuring. 

Article

Teen Driving

Car crashes are the leading cause of death for teens 14 and older. Researchers at the Center for Injury Research and Policy at Nationwide Children’s have done extensive research on teen driving, including graduated driver licensing (GDL) laws: Uncovering the mechanisms of how GDL reduces

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RIO™ Study Reports

To view the latest study reports, please visit The Pediatric Injury Prevention, Education, and Research (PIPER) Program at the Colorado School of Public Health. Below are links to the annual summary reports from the National High School Sports-Related Injury Surveillance Study.

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Shopping Cart Safety

Parents take their children with them on shopping trips every day. Knowing the risks and following shopping cart safety tips can help to prevent injuries while at the store.

Article

Smoke Alarm Study

The objective of this study is to determine the key smoke alarm characteristics that result in successful awakening of children and prompt their rapid escape. 

Article

NEISS

The National Electronic Injury Surveillance System (NEISS) is a statistically valid, injury surveillance system operated by the U.S. Consumer Product Safety Commission (CPSC).

Article

Fireplace Safety

Whether you’re roasting chestnuts or just enjoying the warm glow, fireplaces can help make a home warm and cozy. To a baby, toddler, or young child, flames in a fireplace are a new thing they want to explore.

Article

Ice Hockey

Ice hockey is a popular winter sport in the United States. However, there are more than 20,000 ice hockey-related injuries seen in U.S. emergency departments each year.

Article

Sledding Safety

Sledding and tubing can be a great way to enjoy winter weather. Taking a few safety measures can help keep you and your kids safe on the hills this winter.

Article

Columbus Youth Helmet Ordinance

In the city of Columbus, children younger than 18 years of age are required by law to wear a helmet when they are participating in wheeled sports. Violators may be issued a citation.

Article

Sports-Related Concussion

Researchers in the Center for Injury Research and Policy work on multi-disciplinary teams to investigate several factors related to sports-related concussion including concussion legislation, recovery from concussion, and concussion education and awareness.

Article

Baseball-Related Injury

While baseball is a great way for people of all ages to get out and get some exercise, injuries can and do occur. Taking a few precautions will help reduce the chance of injury.

Article

International Affiliate Faculty Requirements

Purpose The Center for Injury Research and Policy (CIRP) of the Abigail Wexner Research Institute at Nationwide Children's Hospital works globally to reduce injury-related pediatric death and disability.

Article

Dance Related Injuries by the Numbers

Dance is a beautiful form of expression, but it could be physically taxing and strenuous on the human body, particularly for children and adolescents 3 to 19 years of age. 

Article

Distracted Driving

Distracted driving is defined by the National Highway Traffic Safety Administration (NHTSA) as “any activity that diverts attention from driving, including talking or texting on your phone, eating and drinking, talking to people in your vehicle, fiddling with the stereo, entertainment or

Article

Diving Safety

More than 6,500 children and adolescents are treated for diving-related injuries annually. The leading cause of youth diving injuries is collision with the diving board or platform.

Article

USA-China Agricultural Injury Research Training Project Success Stories

The overall goal of the USA-China Agricultural Injury Research Training Project is to increase training and research related to agricultural injuries in China. 

Article

Waterskiing & Wakeboarding

Thousands of water skiers and wake boarders are treated in emergency departments across the US every year. It is important to learn how be safe before you head out onto the water.

Article

Golf Cart Safety

The growing number of golf-cart related injuries has become a concern. The following tips will help keep both drivers and passengers safe while they are using golf carts.

Article

Walking Safely

Walking is a great way to get exercise and enjoy the outdoors. However, kids have a hard time identifying danger and can be seriously injured or killed by cars. 

Article

Skiing & Snowboarding

Skiing and snowboarding are great ways to spend time outdoors during the winter months. Taking a few safety measures can help you have fun and be safe.

Article

Program Application

Deadline for applications: 5:00pm EST, Monday, January 27, 2025 Notification: Accepted applicants will be notified by Monday, February 24, 2025 Submit all application materials to: Gary.Smith@NationwideChildrens.org There is no application form.

Article

Baby Walkers

Many parents believe baby walkers offer their children entertainment, promote walking, and provide a safe baby activity while parents are busy doing something else. However, none of these assumptions are true.

Article

Holiday Road Safety

Holiday season is one of the busiest times of the year on the road. Throughout this time of year, car safety is impacted by last-minute shoppers, social visits and unpredictable weather.

Article

Midwest Injury Prevention Alliance

The purpose of MIPA is to promote the development and sharing of injury prevention planning, evaluation, education and policy strategies, training, research and other initiatives.

Article

Cellphone Use in Young Drivers Study

Dr. Motao Zhu is recruiting for a study about cellphone use and young drivers. The project will last 6 months, during which an app will be installed on your phone and a camera will be installed in your car.

Article

Distracted Driving Study

Dr. Motao Zhu is recruiting for a project about distracted driving. The project will last 6 months, during which an app will be installed on your phone and a camera will be installed in your car.

Article

High School RIO™ Press Releases

To view or print any of the High School RIO™ press releases, click on the title. New National Study Examines Concussion Management in High School Sports - December 1, 2010 Football Injuries in U.S.

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Meet Our Team

Dr. Gary Smith is a professor of Pediatrics, Emergency Medicine and Epidemiology at The Ohio State University. He is founder and director of the Center for Injury Research and Policy of the Abigail Wexner Research Institute at Nationwide Children’s Hospital. 

Article

Detergent Packet Infographic

Learn more about laundry detergent packet dangers.

Article

Muscular Dystrophy Research

Dr. Jerry Mendell and his team have discovered that gene therapy can treat the underlying cause of muscular dystrophy - something that other drugs and medications can't currently do.

Article

March 2012

Dr. Thomas Voit discusses gamma sarcoglycan gene therapy.

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July 2014

Dr. Scott Harper discusses RNAi silencing in limb girdle muscular dystrophy 1A.

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January 2013

Dr. James Ervasti discusses stability of therapeutic forms of dystrophin.

Article

February 2012

Dr. Burghes discusses antisense oligomer treatment in an SMA mouse model.

Article

June 2011

Dr. Paul Martin discusses how the CMAH gene deletion in the mdx mouse model of duchenne muscular dystrophy helps better mimic the more severe aspects of DMD.

Article

May 2012

Dr. Hugh Allen discusses cardiomyopathy in duchenne muscular dystrophy.

Article

News and Announcements

Stay up to date with the latest news coming out of the Office of Technology Commercialization.

Article

Amplifying Copy Numbers to Reduce SMA Severity

Spinal muscular atrophy (SMA) is a collection of different muscle diseases characterized by the selective loss of motor neurons in the spinal cord. Grouped together, SMA is the second leading cause of neuromuscular disease and is the leading genetic cause of death in infants and toddlers.

Article

Gene Therapy Going Strong

Gene Therapy Collaborative Group Targets Neuromuscular Disease At Nationwide Children’s Hospital, gene therapy strategies to reverse or prevent damage caused by muscle-wasting diseases are gaining strength, especially in animal models of human disease.

Article

Replacing Missing Genes

Duchenne muscular dystrophy (DMD) is the most common life-threatening childhood form of muscular dystrophy. It is characterized by progressive weakness and degeneration of skeletal muscles and caused by a mutation in the dystrophin gene.

Article

Circulating "Good" Genes Body-Wide

While Muscle Group members are discovering new targets for drug development, progress will continue to be stunted if the drug can’t reach the central nervous system, a primary player in neuromuscular diseases.

Article

Protein Acts as Antagonist to Strengthen Muscle

Another approach to improving the health of patients with neuromuscular diseases is to treat the life-threatening effects of the diseases, most notably the muscle degeneration that destroys patients’ ability to walk and ultimately takes their lives.

Article

Preventing Muscle Damage Caused by Inflammation

While myostatin blocks muscle differentiation and growth, inflammation contributes to muscle death in neuromuscular diseases. In muscular dystrophy, the immune process is heightened, which contributes to chronic inflammation that kills muscle cells.

Article

Surrogate Genes Help Shield the Muscle

While dystrophin and alpha-sarcoglycan gene replacement focus on replacing mutated genes, Muscle Group studies have also shown value in some existing “healthy” genes.

Article

Frequently Asked Questions

Find answers to the most common questions around technology commercialization.

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Startups

Learn more about our startups that began with research and innovation at Nationwide Children’s.

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Transfer to Transform 2025

Transfer to Transform, published annually online and in print, shares the story of Technology Commercialization at Nationwide Children's — a story of bold thinkers, exciting new technologies and job-producing startups.

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Myology Course Archive

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Early Detection and Personalizing Treatments

While gene therapy techniques continue to develop and show promise for successful application in humans, emphasis is equally being put on early intervention.

Article

Technology Development Fund

The Technology Development Fund provides pre-commercial development support for fast-track proof of concept development/validation work.

Article

September 2010

Dr. Federica Montanaro discusses cardiomyopathy in becker muscular dystrophy.

Article

September 2011

Dr. Jill Rafael-Fortney discusses the effects of Lisinopril and Spironolactone on DMD mice.

Article

March 2013

Dr. Louise Rodino-Klapac discusses alpha 7 integrin as A therapeutic approach to muscular dystrophy.

Article

November 2013

Dr. Louis Chicoine discusses the effect of plasmapheresis in removal of AAV antibodies for gene therapy.

Article

April 2014

Dr. Brian Kaspar discusses a new method for studying ALS, with potential to test therapeutics in individual patients.

Article

September 2013

Dr. Volker Straub discusses the use of muscle MRI in muscular dystrophy.

Article

Rashnonejad Lab Staff

Learn more about principal investigator Afrooz Rashnonejad, MSc, PhD, and her dynamic team in the Rashnonejad Lab.

Article

Rasmussen Lab Staff

Under the direction of Sara Rasmussen, MD, PhD, the Rasmussen Lab is dedicated to investigating the role that Human Endogenous Retrovirus K (HERV-K) has in the cellular transcriptome of pediatric tumors.

Article

Drissi Lab Staff

Learn more about principal investigator Rachid Drissi, PhD, and his dynamic team in the Drissi Lab.

Article

Chandler Lab Staff

Learn more about principal investigator Dawn Chandler, PhD, and her dynamic team in the Chandler Lab.

Article

Roberts Lab Staff

Learn more about Ryan Roberts, MD, PhD, and the lab staff in the Roberts Lab.

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Kendall Lab Staff

Learn more about principal investigator Genevieve Kendall, PhD, and her dynamic team in the Kendall Lab.

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Funding

The Wang Lab appreciates the generous support of funders who share our mission to understand fundamental questions related to cell metabolism, cell cycle, and cell fate determination in various physio-pathological contexts. Explore our major projects.

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Featured Accomplishments

Read news releases about the Center for Biobehavioral Health's featured research projects, grants and awards.

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Behavioral Trials Office

The Behavioral Trials Office is a point of entry service for social and behavioral clinical trials at Nationwide Children's Hospital, and a conduit through which investigators streamline connections to resources throughout the Abigail Wexner Research Institute.

Article

Jackson Lab Staff

Learn more about principal investigator Jamie L. Jackson, PhD, and her dynamic team in the Jackson Lab.

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Gerhardt Lab

Under the direction of Center for Biobehavioral Health Director and Principal Investigator Cynthia Gerhardt, PhD, the Gerhardt Lab explores how children and families are affected by life threatening illnesses such as childhood cancer to develop interventions that improve the experiences of these illnesses. Learn more about the Gerhardt Lab and explore current projects.

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Skeens Lab

Under the direction of Micah Skeens, PhD, APRN, FAAN, the Skeens Lab investigates the psychosocial and biobehavioral outcomes of children facing cancer and undergoing hematopoietic stem cell transplants.

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Intelligent Futures Research Lab

Under the direction of Emre Sezgin, PhD, the goal of the Intelligent Futures Research Lab is to build a healthier future for all children and families using intelligent methods and approaches to scientific research and development.

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Current Studies

Learn more about the current studies in the Child Brain and Development Lab.

Article

Keim Lab Staff

Learn more about principal investigator Sarah Keim, PhD, MA, MS, and her dynamic team in the Keim Lab.

Article

Current Studies

Learn about current Keim Lab studies.

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Skeens Lab Staff

Learn more about principal investigator Micah Skeens, PhD, APRN, FAAN, and her dynamic team in the Skeens Lab.

Article

The Child Brain and Development Lab Staff

Learn more about principal investigator H. Gerry Taylor, PhD, and his dynamic team in the Taylor Lab.

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Participation FAQs

Find answers to some of our most frequently asked questions.

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For Researchers

Access Keim Lab resources for researchers.

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Moscato Lab Staff

Learn more about principal investigator Emily Moscato, PhD, and her dynamic team in the Moscato Lab.

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Skeens Lab Research Projects

The Skeens Lab's mission extends beyond research; they strive to develop innovative digital health interventions, with a specific focus on underrepresented and vulnerable populations. Learn about the lab's current and past research projects.

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Nahata Lab

Under the direction of principal investigator Leena Nahata, MD, the Nahata Lab focuses on improving reproductive and psychosocial outcomes in pediatric populations at risk for infertility. Learn more about the Nahata Lab and explore featured news and publications as well as information about current studies.

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Malerba Lab

Under the direction of principal investigator Paola Malerba, PhD, the Malerba Lab is focused on studying sleep rhythms in the human brain. 

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Jackson Lab

Under the direction of principal investigator Jamie Lu Jackson, PhD, the Jackson Lab examines how individuals with congenital and acquired heart disease manage their illness and emotional wellbeing across their lifespan. Learn more about the Jackson Lab by exploring featured news and publications as well as information about current studies and training and volunteer opportunities.

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Taylor Lab

The Child Brain & Development Lab studies neurodevelopmental outcomes of brain-related conditions to inform more effective approaches to identification and treatment of learning and behavior problems in children with these conditions. Learn more about Principal Investigator H. Gerry Taylor, PhD, lab staff and current studies and collaborations.

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Moscato Lab

The Moscato Lab, led by Emily Moscato, PhD, focuses on designing, testing and implementing equitable behavioral interventions to improve quality of life and neurodevelopmental trajectories for young children with chronic conditions impacting the central nervous system.

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Keim Lab

Principal Investigator Sarah Keim, PhD, and the Keim Lab examine how children learn and grow and how nutrition affects health and development, focusing on infants, toddlers, and young children, especially those born prematurely. Learn more about the Keim Lab and explore current studies, featured research and resources for study participants.

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Gerhardt Lab Staff

Learn more about principal investigator Cynthia Gerhardt, PhD, and her dynamic team in the Gerhardt Lab.

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Biobehavioral Outcomes Core

The Biobehavioral Outcomes Core assists investigators who want to incorporate behavioral assessments in their research.

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Post-Baccalaureate Training Program

The Post-Baccalaureate Training Program includes a wide range of experienced research professionals, with the discussion topics ranging from graduate and medical school application preparation to enrichment of a wide range of research skills.

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Application

Eligibility Applications will be accepted from both MD physician-scientists and PhD applicants with training in health, psychology, epidemiology, or related fields.

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Evidence-Based Guidelines

See how our research impacts clinical care through our contribution to national and international evidence-based guidelines.

Meet Our Faculty

Meet Our Team

Learn more about the team of principal investigators at the Center for Biobehavioral Health.

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Garg Lab Staff

Learn more about principal investigator Vidu Garg, MD, and his dynamic team in the Garg Lab.

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Cardiovascular Research Shared Resource Core

The Cardiovascular Research Shared Resource is available to facilitate both basic and translational research for basic science and clinical faculty.

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Zhao Lab

Under the direction Mingtao Zhao, DVM, PhD, the Zhao Lab is exploring the genetic basis of cardiovascular development and congenital heart disease using patient-derived induced pluripotent stem cells (iPSCs).

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Summer 2025 Training Opportunities for Undergraduate Students

Rising juniors and seniors can explore science careers and experience multidisciplinary research at AWRI firsthand through a 10-week, paid summer research opportunity funded by the American Heart Association.

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Garg Lab

Under the direction of Vidu Garg, MD, the Garg Lab focuses on identifying the genetic contributors to congenital heart defects.

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McConnell Lab

Under the direction of Patrick McConnell, MD, the McConnell’s Lab focuses on studying biological models of heart function, pathophysiology and cardiac assisting devices.

Article

Zhao Lab Staff

Learn more about principal investigator Mingtao Zhao, DVM, PhD, and his dynamic team in the Zhao Lab.

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PIVOTAL Network

The PIVOTAL Network is a group of healthcare providers, institutions, and researchers working in collaboration to determine the best approach to treat preterm infants diagnosed with patent ductus arteriosus, commonly referred to as a PDA.

Meet Our Team

Learn more about director Vidu Garg, MD, and his team of principal investigators at the Center for Cardiovascular Research.

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Jang Lab

Under the direction of Jihyun Jang, PhD, the Jang Lab is exploring how non-genetic factors, particularly epitranscriptomics, regulate complex physiological and pathological processes during heart development.

Article

Trask Lab

Under the direction of Aaron Trask, PhD, the Trask Lab's research focuses on studying processes involved in adverse micro- and macro-vascular remodeling in disease.

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Li Lab

Under the direction of Deqiang Li, MD, PhD, the Heart Development and Regeneration Lab at Nationwide Children's Hospital aims to understand the fundamental mechanisms of cardiac cell proliferation and differentiation and how signaling communications instruct specific processes.

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Primary Care Research Network

The Nationwide Children’s Hospital Primary Care Research Network (PCRN) is a consortium of pediatric primary care practices focused on improving child health and family outcomes through high-quality research in primary care settings. Additionally, the Pediatric Primary Care Research Affinity Group (PPC-RAG) awards supplemental funding on an annual basis for collaborative projects.

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Neurodevelopmental Research Affinity Group Members

The Neurodevelopmental Research Affinity Group is made up of expects in biobehavioral health, child development, neurology, psychology and more. Learn more about its members.

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Supplemental Pilot Funding

PCRN and the Pediatric Primary Care Research Affinity Group (PPC-RAG) at Nationwide Children's offer small supplemental funding awards to support new or ongoing research projects, including small pilot projects to support the development of larger projects, to help advance primary care research.

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Application Process

All projects applying to conduct research through the Primary Care Research Network (PCRN) should complete this application.

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Current Studies

Below is a list of the ongoing studies currently active in the PCRN. Click on each study to learn more.

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Featured Projects and Publications

Acquired Brain Injury

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Critical Illness and Injury Interdisciplinary Research

The mission of the Critical Illness and Injury Interdisciplinary Research Group (CI3RG) is to foster collaborative, interdisciplinary science in critical illness and injury discovery. They aim to facilitate collaboration among investigators throughout Nationwide Children's and across OSU campus by cross-pollination of research spanning diverse methodologies, with the ultimate goal of bridging investigation from the cell to the community.

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Blood Disease Research Affinity Group (BDRAG)

The Blood Disease Research Affinity Group (BDRAG) promotes cutting-edge collaborative research among clinical and research faculty and trainees working on blood, vascular science and related disciplines at Nationwide Children’s and The Ohio State University to positively impact the prevention and care of childhood blood diseases. BDRAG also aims to increase awareness of blood disease research on these campuses and elevate educational opportunities for trainees.

Meet Our Team

Meet our Blood Disease Research Affinity Group faculty.

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Lung Inflammation Research Affinity Group

The Lung Inflammation Research Affinity Group (LIRAG) facilitates collaboration on research that drives understanding of the mechanisms underlying lung disease broadly, with a special focus on those that involve inflammatory diseases of (or in) the lung.

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Neurodevelopmental Research Affinity Group

The mission of the Neurodevelopmental Research Affinity Group is to facilitate research collaborations on neurodevelopment and neurodevelopmental disorders in children by increasing awareness of common research interests, creating new synergies in research methods, and broadening the scope and outreach of research activities.

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Oral-GI Microbiology Research Affinity Group

The Oral and GI Microbiology Research Affinity Group (OGM RAG) at Nationwide Children’s Hospital will bring together like minded clinicians and basic scientists that are actively involved in research in oral and gastrointestinal microbiology as it affects human disease.

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PARENT

Nationwide Children’s is starting a text service for parents of babies 0-15 months old. Parents will get weekly tips, resources, and reminders based on their baby’s age and development! What Are the Key Details of the Text Messaging Service? Who Will Receive Texts? All families with

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Bailey Lab

Under the direction of Michael Bailey, PhD, the Bailey Lab investigates the integrative mechanisms by which the gut microbiome – a diverse community of microorganisms that coexist within our gastrointestinal tract – influences health.

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Feng Lab

Under the directions of Zongdi Feng, PhD, the Feng Lab focuses on understanding the life cycle and pathogenesis of human hepatitis viruses and identifying methods to improve the outcome of diseases caused by these infections.

Article

Bagaitkar Lab

The Bagaitkar Lab studies the complex interactions between innate immune cells, epithelial cells, and microbial colonizers at the oral mucosal barrier. 

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Kapoor Lab

Many important human viruses lack appropriate animal models, restricting studies of viral pathogenesis and immunity. The Kapoor Lab is characterizing several newly identified rodent viruses to develop informative surrogate models for their human homologs.

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Bailey Lab Staff

Learn more about principal investigator Michael Bailey, PhD, and his dynamic team in the Bailey Lab.

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Fetal Research Affinity Group Members

The Fetal Research Affinity Group is made up of experts in fetal therapy, neonatology, genetics, molecular biology and others perinatal fields. Learn more about its members.

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Molecular and Cellular Medicine-Research Affinity Group

The Molecular and Cellular Medicine-Research Affinity Group (MCM-RAG) will stimulate the scientific interchange between researchers from the Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital and The Ohio State University (OSU) who utilize molecular, cellular, and bioinformatics approaches to elucidate disease mechanisms.

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MCM-RAG Members

The Molecular and Cellular Medicine-Research Affinity Group is made up of a steering committee and members from both Nationwide Children's Hospital and The Ohio State University. Learn more about its members.

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Fetal Research Affinity Group

The Fetal Research Affinity Group will bring together experts in fetal therapy, neonatology, genetics, molecular biology and others perinatal fields to develop and advance cutting-edge therapies that can be used to treat fetuses and neonates with a wide range of genetic and medical disorders.

Publications

Here are examples of recent publications that arose from collaborative projects between Nephrology and Urology Research Affinity Group (NURAG) investigators: Predicting Outcomes for Children with Congenital Obstructive Uropathy McLeod DJ, Ching CB, Sebastião YV, Greenberg JH, Furth SL,

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Gunn Lab

The Gunn Lab's primary focus is determining the molecular mechanisms underlying chronic carriage of Salmonella Typhi in the gallbladder, which is mediated by biofilm formation on gallstones. Typhoid fever, caused by S. Typhi, is a global disease that disproportionately affects children.

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Pediatric Trauma and Burn Research Affinity Group

The mission of the Pediatric Trauma and Burn Research Affinity Group at Nationwide Children's Hospital is to facilitate team science and innovative pilot studies by establishing multidisciplinary collaborations.

Meet Our Team

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Gunn Lab Staff

Learn more about principal investigator John Gunn, PhD, and his dynamic team in the Gunn Lab.

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Feng Lab Staff

Learn more about principal investigator Zongdi Feng PhD, and his dynamic team in the Feng Lab.

Meet Our Team

Learn more about interim director, Joanne Turner, PhD, and the team of principal investigators at the Center for Microbe and Immunity Research.

Meet Our Team

Learn more about director Henry Xiang, MD, MPH, PhD, MBA, and his team of principal investigators at the Center for Pediatric Trauma Research.

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Featured Accomplishments

Explore achievements and publications authored by the team in the Center for Pediatric Trauma Research.

Education and Training Programs

A wide range of education and training opportunities are available for students and fellows, including the Global Training Program.

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Featured News

Stay up to date on the latest news releases coming out of the Center for Pediatric Trauma Research.

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Medical Student Research Program

Each year, the Center for Pediatric Trauma Research seeks medical students interested in conducting research related to pediatric trauma. This program, in conjunction with physicians at Nationwide Children’s Hospital, aims to provide medical students with firsthand research experience in the field of pediatric trauma.

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Global Training Program

The Global Training Program of the Center for Pediatric Trauma Research seeks to promote optimal care of the injured patient by enhancing treatment and minimizing harm following injury.

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Global Health-China Medical Program

The Global Health-China Medical Program at Nationwide Children’s Hospital seeks to provide a short-term opportunity, 1-3 months for residents and fellows or 1 week for physicians, for them to travel to the People’s Republic of China to enhance their knowledge and skills in pediatric care.

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Past Global Scholars

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Pediatric Surgery Rotating Observation in Columbus for Excellent Student Scholars (PROCESS)

PROCESS is an international student program carried out in cooperation with Surgical Academic Faculty in Poland (including the former Minister of Health). The program selects students to grant a 1 month observership at Nationwide Children's Hospital from competing student-applicants from 12 medical universities in Poland.

Research Publications

Learn about research-focused publications at Nationwide Children's Hospital. 

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Lab Staff

Mitchel Stacy, PhD Principal Investigator Mitchel.Stacy@NationwideChildrens.org Mitchel R. Stacy, PhD, is a principal investigator in the Center for Regenerative Medicine and an assistant professor of Surgery at The Ohio State University College of Medicine.

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Onohara Lab

Under the direction of Daisuke Onohara, MD, PhD, the Onohara Lab is focused on translational research, specifically in establishing complex large animal models and developing new surgical / interventional treatments.

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Onohara Lab Staff

Learn more about principal investigator Daisuke Onohara, MD, PhD, and his dynamic team in the Onohara Lab.

Meet Our Team

Learn more about director Christopher Breuer, MD, and his team of principal investigators at the Center for Regenerative Medicine.

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Barker Lab

The Barker Lab studies wound healing and disorders of abnormal wound healing. As the primary research laboratory for the Department of Plastic Reconstructive Surgery, Dr. Jenny Barker facilitates innovative and collaborative translational science for would care and plastic surgery patients.

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Stacy Lab

Under the direction of Mitchel Stacy, PhD, the Stacy Lab is focused on the development and validation of quantitative imaging techniques that possess potential for clinical translation, with particular interest and focus on imaging of cardiovascular disease.

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Featured In the News

Each year, preterm birth affects nearly 500,000 babies, or 1 in every 8 infants born in the United States. Preterm birth is when an infant is born before 37 weeks of pregnancy, and it is the leading cause of infant mortality and neurological disabilities in children. Dr.

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Ohio Perinatal Research Network

The Ohio Perinatal Research Network (OPRN) is a collaborative with the goal of examining risk factors, associated complications and ultimately the prevention of preterm births.

Meet Our Team

Learn more about the faculty and staff at the Center for Perinatal Research.

Meet Our Team

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Britt Lab

The Britt Lab studies how inflammation affects airway structure and function in asthma, cystic fibrosis, and bronchopulmonary dysplasia. Their goal is to define physiological and immunological mechanisms that drive chronic airway disease, while also developing novel strategies that can alleviate disease and improve airway function.

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Britt Lab Staff

Learn more about principal investigator Rodney D. Britt Jr, PhD, ATSF, and his dynamic team in the Britt Lab.

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Chen Lab

The Chen Lab examines pathways involved in vascular remodeling and smooth muscle cell proliferation, the pathogenic hallmarks of PH. Its research is focused on the phosphodiesterase 3 (PDE3) pathway and the distinct function and activity of each isoform (PDE3A and PDE3B) and their mechanistic interaction with the nitric oxide (NO)-cGMP pathway, which remain largely unknown.

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Steelesmith Lab

Under the direction of Danielle Steelesmith, PhD, the Steelesmith Lab focuses on rural and urban disparities in mental health services and outcomes, such as suicide and deaths of despair.

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Bridge Lab

The Bridge Lab focuses on the epidemiology of suicidal behavior in young people and neurocognitive vulnerability to suicidal behavior, as well as improving the quality of care for suicidal youth and adolescents who have attempted suicide.

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Ruch Lab

The Ruch Lab is focused on improving behavioral health and suicide related outcomes across youth serving systems (juvenile justice, child welfare, healthcare, education) to better inform suicide prevention strategies.

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Fontanella Lab

Under the direction of Cynthia Fontanella, PhD, the Fontanella Lab is interested in examining and improving quality of care for children and youth. Their primary goal is to understand the relationship between suicide and health service use.

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Caring Contacts

As part of Nationwide Children’s Hospital’s commitment to a Zero Suicide mission, the CSPR created a program that sends a series of 19 caring messages over the course of a year to youth who have been treated for suicidal thoughts or behaviors in several of our acute Behavioral Health

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Fontanella Lab Staff

Learn more about principal investigator Cynthia Fontanella, PhD, and her dynamic team in the Fontanella Lab.

Meet Our Team

Learn more about director Jeff Bridge, PhD, and his team of principal investigators at the Center for Suicide Prevention and Research.

Research Labs

Learn more about the research labs in the Center for Suicide Prevention and Research.

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Opportunities

Learn about Chandler Lab staff opportunities.

Featured Research Topics

Learn more about the research projects being done in the Center for Suicide Prevention and Research.

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Health Service Use

Health Service Use Prior to Suicide by Children and Adolescents 

• Clinical Profiles in Medicaid Enrolled Youth
• Health Service Use in Child Welfare Involved Youth

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Regional Differences

Regional Differences in Suicide

• Rural and Urban Differences in Youth Suicide
• Mapping Suicide Rates in Ohio
• Contextual Factors Associated With Suicide Rates in the United States

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Media and Suicide

Impact of the Media and Suicide

• Netflix’s 13 Reasons Why
• Newspaper Adherence to Media Reporting Guidelines

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Racial/Ethnic Disparities in Youth Suicide

Racial/Ethnic Disparities in Youth Suicide 

• Age-Related Disparities in Suicide
• Suicide in Black Youth

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Suicide Risk Screening and Interventions

Suicide Risk Screening and Interventions

• Ask Suicide Screening Questions (ASQ)
• Suicide Risk Screening in Primary Care
• Effect of Motivational-Interviewing Intervention

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Age Trends

Age Trends in Youth Suicide

• Suicide in Young Children
• Suicide in School-Aged Youth and Adolescents
• Suicide Trends in Elementary School-Aged Youth

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Epidemiology

Research on Patterns and Risk Factors Related to Suicide and Suicidal Behaviors 

• Risk Factors for Self-Harm Among Youth With Bipolar Disorder
• Cannabis Use, Self-Harm and Mortality Risk Among Youth With Mood Disorders
• Risk Factor for Self-Harm Among Youth With First Episode Psychosis

CSPR Blog Posts

Read blog posts written by Center for Suicide Prevention and Research staff.

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Special Populations

Special Populations (Including Youth in the Child Welfare and Juvenile Justice System) 

• Mortality of Juvenile Justice Involved Youth

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Liu Lab

The Liu Lab studies inflammation, immunity, sepsis and more using both animals and cells.

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Slaughter Lab

The Slaughter Lab aims to improve outcomes important to neonatal patients and their families through large patient-focused cohort investigations and randomized trials.

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Reynolds Lab

The main focus of the Reynolds Lab involves elucidating the mechanisms involved in airway epithelial tissue repair using mouse models and human cell cultures to pave the way for the eventual use of human tissue stem cell therapy to treat cystic fibrosis and other forms of chronic lung disease.

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Nelin Lab

The Nelin Lab’s focus is on inflammatory lung injury and the mechanisms leading to lung diseases, particularly bronchopulmonary dysplasia (BPD).

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Lynch Lab

Under the direction of Thomas Lynch, PhD, the Lynch Lab leverages cutting-edge animal models, cell and tissue culture techniques, and transcriptomics to study region-specific cell differentiation, renewal and regenerative plasticity in the conducting airways of the lung.

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Neuromuscular Gross Motor Outcome (GRO)

The Neuromuscular GRO is a gross motor outcome measure designed to assess whole body strength, motor development and function for all levels of ability across the lifespan in those diagnosed with neuromuscular disease.

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Lowes Lab Ambulatory Status Algorithm (LASA)

The Lowes Lab Ambulatory Status Algorithm (LASA) is an ambulatory status algorithm designed to classify individuals with neuromuscular disease into one of three categories: ambulatory, transitional or non-ambulatory based on simple patient or parent interview questions.

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Affiliations

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Past Events

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The Student Urinary Tract Program in Education and Research

The National Institutes of Health (NIH) funded Student Urinary Tract Program in Education and Research (SUPER) Summer Training Program is for undergraduate students interested in an integrated research and clinical experience.

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Lets Connect

Virtual Professional Consultations and Collaborations Let’s Connect is a free consultation and mentoring service for injury professionals and trainees to connect with faculty and senior staff in the Center for Injury Research and Policy (CIRP) at Nationwide Children's Hospital in Columbus,

Meet Our Team

Our office is ready to help the ideas and innovations of Nationwide Children’s employees flourish and connect external partners with exciting opportunities.

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Available Technologies

Browse our technology catalog and connect with our licensing associates.

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Flow Cytometry and Immune Monitoring Core

The Flow Cytometry Core lab offers several platforms on which to do flow analysis and/or cell sorting. 

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Clinical and Translational Science Institute

The Ohio State University Clinical and Translational Science Institute (CTSI) is a collaboration among the University, The Ohio State University Wexner Medical Center and Nationwide Children's Hospital dedicated to turning the scientific discoveries of today into life-changing disease prevention strategies and the health diagnostics and treatments of tomorrow.

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Clinical Research Services

Clinical Research Services (CRS) is a portal through which clinical investigators access streamlined coordination of services necessary to initiate clinical research projects, regardless of funding source.

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Biologics Manufacturing

Biologics Manufacturing maintains facilities, equipment and personnel for manufacturing a wide range of cellular therapeutic products for clinical trials including natural killer (NK) cells, CAR NK and CAR T cells and a tissue engineered vascular graft.

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Motao Zhu Team

Motao Zhu, MD, MS, PhD Principal Investigator Dr. Zhu is a professor of pediatrics and epidemiology at Nationwide Children’s Hospital and The Ohio State University College of Medicine. With doctoral training in epidemiology and medicine, and active research for about 20 years, Dr.

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Administrative Staff

Nichole Guzick Administrative Lead Email Nichole joined CIRP in October 2023 as the Administrative Lead. She attended Ohio School of Phlebotomy and became a Certified Clinical Medical Assistant. Outside of work, Nichole loves spending time with family and friends.

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Backyard Safety

Playing outside is a great way for kids to exercise and have fun. However, backyards can be full of potential dangers. Parents should take steps to make sure their yards are safe for kids to enjoy.

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Breuer Lab

The focus of the Breuer and Shinoka Labs is to design a tissue engineered vascular graft (TEVG) that can be used during surgery that, over time transitions to a normal blood vessel that will grow with our pediatric patients.

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Lab Staff

Learn more about Toshiharu Shinoka, MD, PhD, and his dynamic team in the Shinoka Lab.

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Jerry R. Mendell

Jerry R. Mendell, MD, is an advisor to the Jerry R. Mendell Center for Gene Therapy in the Abigail Wexner Research Institute at Nationwide Children’s and to Sarepta Therapeutics. He is also an emeritus professor of Pediatrics at The Ohio State University.

About Our Research

Integrating research and clinical care is at the heart of the Nationwide Children's Hospital strategic plan. Nationwide Children’s is focused on ensuring optimal health outcomes, from advancing precision therapeutics to improving population health and community development.

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Shinoka Lab

Under the direction of Toshiharu Shinoka, MD, PhD, the Shinoka Lab works closely with Dr. Christopher Breuer's lab in optimizing Tissue Engineered Vascular Grafts (TEVGs) in animal models, with the goal of translating the work to humans.

Children and Research

Research drives advances in the treatment, diagnosis and prevention of diseases. But children are often left out of research, leaving health providers and families with fewer options for care.

Patient-Centered Pediatric Research Program

The Patient-Centered Pediatric Research Program prepares postdoctoral fellows to engage in independent outcomes research in child health settings and become leaders in the conduct of patient- and family-centered outcomes research.

Training Programs

A wide range of training opportunities are available for students and fellows, including the Post-Baccalaureate Training Program and the Patient-Centered Pediatric Research Program.

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FDA Approval

The FDA has issued an accelerated approval for a second gene therapy developed at Nationwide Children's Hospital, bringing hope to children with Duchenne muscular dystrophy.

Our People

Our research faculty is dedicated to discovering new methods of diagnosing, treating and preventing diseases in kids everywhere.

Behavioral Health Clinical Research

Learn more about clinical research relating to behavioral health services.

Neurology & Neurosciences Clinical Research

Learn more about clinical research relating to neurology and neurosciences.

Our Labs

Learn more about the research being done in the Center for Biobehavioral Health labs.

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Hoskinson Lab

Under the direction of principal investigator Kristen Hoskinson, PhD, the Hoskinson Lab studies the long-term effects of pediatric chronic illnesses that affect brain functioning, with a focus on parts of the brain that support social development, complex problem solving, and day-to-day adjustment. Learn more about current studies and collaborations with other research groups.

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Neuroimaging and Behavior Research Group

The mission of the Neuroimaging and Behavior Research Group (NIBREG) is to facilitate brain-behavior research at Nationwide Children’s Hospital.

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Hoskinson Lab Staff

Learn more about principal investigator Kristen Hoskinson, PhD, and her dynamic team in the Hoskinson Lab.

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Participation FAQs

Find answers to the most frequently asked questions about our studies.

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Nelson Lab

Principal Investigator Eric E. Nelson, PhD, and the Brain Development and Social Cognition Lab study how the brain matures across development, including how brain changes that happen during adolescence affect social behavior, emotional responses and cognitive function. Learn more about lab staff and review current studies, participation FAQs and other resources.

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Ching Lab

Under the direction of Christina Ching, MD, the Ching Lab uses a mouse model of infection to understand the host response to urinary tract infection. In addition, the lab performs in vitro simulation of infection and collects human urine samples to look for differences in components of the urine in those individuals susceptible to infection.

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Jackson Lab

Under the direction of Ashley Jackson, PhD, the Jackson Laboratory has a primary research focus on congenital and acquired urinary tract obstruction (UTO).

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Ruiz-Rosado Lab

Under the direction of Juan de Dios Ruiz-Rosado, PhD, the Ruiz-Rosado lab focuses on understanding the cellular immune mechanisms that contribute to the resistance or susceptibility to urinary tract infections, particularly acute pyelonephritis (APN), and the development of renal scarring following APN. 

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Zepeda-Orozco Lab

Under the direction of Diana Zepeda-Orozco, MD, MS, the Zepeda-Orozco Lab studies the implications of tubular epithelial cells mitochondrial metabolism and oxidative stress in acute kidney injury and chronic kidney disease progression.

Urology Clinical Research

Learn more about clinical research relating to urology.

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Becknell Lab

Under the direction of Michael Brian Becknell, MD, PhD, the Becknell Lab studies the mechanisms responsible for kidney injury and recovery in response to urinary tract obstruction and infection.

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Cara Fuentes Lab

Under the direction of Gabriel Cara Fuentes, MD, PhD, the Cara Fuentes Lab's mission is to improve the quality of life and health of children suffering from rare protein-spilling kidneys diseases, with a primary focus on idiopathic nephrotic syndrome.

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Spencer Lab

Under the direction of John David Spencer, MD, the Spencer Lab focuses on the function and regulation of antimicrobial proteins in the Ribonuclease A Superfamily.

Meet Our Team

The Kidney and Urinary Tract Center offers patients access to personalized care plans for the treatment of their urologic and kidney issues through streamlined, collaborative visits with our surgical and medical experts in both nephrology and urology. All our expert physicians are also active in research, and many focus on topics specific to the conditions and patients seen in the combined clinic.

Research Labs

Learn more about the research being done in the Kidney and Urinary Tract Center.

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Baker Lab

Under the direction of Linda Baker, MD, the Baker Lab studies the genetics of genitourinary congenital conditions, with a primary focus on Prune Belly Syndrome (PBS).

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Clinical Research FAQs

Learn more about frequently asked questions related to clinical research.

Training Programs

Training opportunities are available for students including The Student Urinary Tract Program in Education and Research (SUPER) Summer Training Program.

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Brain Development and Social Cognition Lab Staff

Learn more about principal investigator Eric Nelson, PhD, and his dynamic team in the Brain Development and Social Cognition Lab.

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Current Studies

Learn more about the current studies in the Brain Development and Social Cognition Lab.

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What To Expect

Learn more about what to expect when participating in a study with the Brain Development and Social Cognition Lab.

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O'Brien Wynkoop Lab

Under the direction of Nicole F. O'Brien, MD, and Hunter Wynkoop, MD, the O'Brien Wynkoop Lab exists to explore global health research with a major focus on severe malaria, one of the leading causes of pediatric death and long-term morbidity on the African continent.

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Spencer Lab Staff

Learn more about principal investigator John David Spencer, MD, and his dynamic team in the Spencer Lab.

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O'Brien Lab

The O'Brien Lab, led by Sarah O'Brien, MD, MSc, focuses on the intersection between women’s health and hematology.

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Bline Lab Staff

Learn more about principal investigator Katherine Bline, MD, and her dynamic team in the Bline Lab.

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About NURAG

The Nephrology and Urology Research Affinity Group (NURAG) is composed of medical faculty, residents and fellows comprising the Nephrology and Urology programs at Nationwide Children’s Hospital. NURAG also includes members of The Abigal Wexner Research Institute at Nationwide Children’s whose research projects focus on the fields of nephrology, urology and associated disciplines.

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Bline Lab

Under the direction of Katherline Bline, MD, the Bline Lab focuses on the host immune responses to severe lower respiratory tract infections in children, with an emphasis on the role of myeloid-derived suppressor cells (MDSC).

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Nephrology and Urology (NURAG)

Members of the Section of Nephrology and Hypertension also participate in the Nephrology and Urology Research Affinity Group (NURAG). NURAG is composed of medical faculty, residents and fellows from the Nephrology and Urology programs at Nationwide Children’s Hospital. NURAG also includes members of the Abigail Wexner Research Institute at Nationwide Children’s whose research projects focus on the fields of nephrology, urology and associated disciplines.

Affinity Groups

Led by a tenured, NIH funded investigator, the goal of a Research Affinity Group is to: Stimulate multidisciplinary collaboration and scientific interchange among basic science and clinical investigators relating to a particular disease.

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Dennis R. Durbin

Dennis R. Durbin, MD, MSCE, is president of the Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital, a professor of Pediatrics at The Ohio State University College of Medicine and vice chair for Research in the Department of Pediatrics.

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Chisolm Lab Staff

Learn more about Deena Chisolm, PhD, and her dynamic team in the Chisolm Lab.

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Chisolm Lab

Under the direction of Deena Chisolm, PhD, the Chisolm Lab focuses on studying health equity at the intersection of communities, health systems, and health policies.

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CSOR Lab Staff

Learn more about co-directors Kyle Van Arendonk, MDm PhD, and Daryl McLeod, MD, MPH, and their dynamic team in the Center for Surgical Outcomes Research.

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Center for Surgical Outcomes Research (CSOR)

The mission of CSOR is to improve children's' care through a comprehensive, patient-centered surgical outcomes research program to determine the optimal management of surgical diseases in children.

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Prevention

CSPR helps schools and community organizations in Ohio implement evidence-based prevention strategies. John P. Ackerman, PhD, and his team have provided training to many schools throughout central and southeastern Ohio, using an enhanced SOS Signs of Suicide prevention programming model.

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Services

Our Labs

Learn more about the research being done in the Center for Microbe and Immunity Research labs.

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Besner Lab Staff

Learn more about principal investigator Gail Besner, MD, and her dynamic team in the Besner Lab.

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Besner Lab

The Besner Lab at Nationwide Children’s aims to eliminate necrotizing enterocolitis (NEC) and its downstream consequences.

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Flanigan Lab

Under the direction of Kevin Flanigan, MD, the Flanigan Lab focuses on the genetic and molecular characterization of inherited neuromuscular diseases, and toward the development of therapies directed toward these diseases.

Our Labs

Learn more about the research being done in the Center for Perinatal Research.

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About

Learn more about the Biopathology Center, part of the Abigail Wexner Research Institute at Nationwide Children’s Hospital.

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Resources

Learn more about the resources offered by the Biopathology Center at Nationwide Children's Hospital.

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Histopathology Core

The Histopathology Core provides exceptional services to internal investigators, including laboratory procedures in histology, electron microscopy and Atomic Force microscopy.

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Other Services

Discover more about our additional services, including protocol development, biospecimen kits, and informatics.

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Laboratory Services

Standard operating procedures and best practices for biospecimen processing, pathology review and laboratory services.

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Biorepository

Explore how the Biopathology Center at Nationwide Children’s Hospital expertly manages biospecimen storage and distribution.

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Bicycle Safety

Every year in the US, thousands of children are treated for bicycle-related injuries. Many of these injuries can be prevented if children follow bicycle safety rules and wear helmets. 

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Lawn Mower Safety

Thousands of children suffer severe injuries from lawn mowers every year. However, most of the injuries from lawn mowers can be prevented by following a few simple steps.

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Burns and Scalds

On average, 120,000 children younger than 21 are treated in hospital emergency departments for burn-related injuries each year.

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Furniture and TV Tip-overs

Most parents do not think of furniture and TVs as dangerous. When children play in the house, they often use dressers and shelves as climbing toys, leading to tip-overs.

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Cribs, Playpens and Bassinets

Parents and caregivers rely on cribs to protect children while they sleep. However, more than 9,500 injuries related to cribs, playpens and bassinets are seen in U.S. emergency departments each year.

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Summer Safety

Summer is a favorite time of year for many children. Help make sure your children have a fun, safe summer by reviewing some tips to prevent injury.

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Poisoning

Every year in the United States, there are over 2.4 million poison exposures. A poison is something that can make you sick if you eat, drink, touch, or breathe it. 

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Halloween Safety

Halloween is a time for fun for all ages. However, parents, children and community members must remember safety on this day filled with fantasy. Check out the following tips.

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Bicycle Helmets

Riding bicycles is a great way for families to have fun and spend time outside. However, riding a bicycle can also be dangerous. Many serious injuries can be prevented by wearing a helmet.

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Bunk Bed Safety

However, an average of 36,000 bunk bed-related injuries occur every year to children in the United States. Injuries can happen when kids are playing around the bunk bed or when they are sleeping. 

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Holiday Safety

Shopping for presents, decorating the house and visiting relatives make the holidays a fun and exciting time of year. Help keep your family healthy at the holidays by following a few safety tips.

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Drowning Prevention

Every year in the US, more than 1,000 children die from drowning, and many more suffer life-changing injuries. Parents need to be aware of drowning dangers and take steps to prevent it.

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Portable Pool Safety

During the summer in the U.S., a child drowns every 5 days in a portable pool. By taking a few precautions, parents can help children remain safe as they cool off during the summer.

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Tree House Safety

Building and playing in tree houses is a favorite activity for young children. Though a tree house can be a place of great fun and imagination, unfortunately it can also lead to serious injury.

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Snow Shoveling

Each year, snow shoveling leads to approximately 100 deaths and 11,500 injuries and medical emergencies that require treatment in an emergency department.

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Cooking Safety

Cooking is a common cause of injury in the home and the leading cause of home fires. Stoves, ovens, toaster ovens and microwaves can all be sources of kitchen fires. 

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Bathtub and Shower Safety

Every year, more than 43,000 children receive emergency treatment for bathtub- and shower-related injuries. Many of these injuries can be prevented by following safety tips.

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Computer-Related Injuries

The computer workstation or home office is not a place many parents think about making safe. However, using and moving computers can cause injuries.

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Magnets

High-powered magnets are small, shiny magnets made from powerful rare earth metals. High-powered magnets have caused thousands of injuries and are considered to be among the most dangerous ingestion hazards in children.

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Choking Prevention

Choking is a year-round hazard among children and a leading cause of injury and death, especially among children 3 years of age and younger.

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Stair Safety

While the number of stair-related injuries did show a declining trend, these types of injuries continue to be a common source of injury among young children.

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College Fire Safety

In order to protect college students from fires, it is important that they understand the risks in their new environment and take appropriate safety measures.

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Fire Safety for Children

When a house fire starts, children can become very afraid and confused. With as little as two minutes to escape unharmed, there is not enough time to plan a safe escape route when the alarm sounds.

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Skateboarding

Skateboarding can be a fun and competitive activity. However, an estimated 64,500 kids age 5-19 are treated in U.S. emergency departments for skateboard-related injuries each year. 

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Pool Safety

Swimming is a great way to cool off during the hot summer. Parents and caregivers need to do their part to keep kids safe in the pool and prevent drowning.

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Baby Gates

About 5 children under the age of 7 are treated in United States hospital emergency departments every day because of baby gate-related injuries.

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Staying Home Alone

All parents will someday ask themselves if their child is ready to stay home alone. Before leaving your child home alone, make sure they are ready and set rules to keep them safe.

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Hot Tubs

Many people use hot tubs, whirlpools and spas for relaxation and fun. Hot tub owners and parents should take proper safety steps to protect children from hot tub-related injuries.

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Fires and Burns

Homes today contain more man-made (synthetic) materials that burn much faster, leaving families with as little as two minutes to escape a fire.

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Home Fire Safety

No one expects a fire to start in their home, but sadly, house fires occur more often than you might think, so it is important to be prepared.

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Children Playing with Fire

Every year, children playing with fire cause hundreds of deaths and injuries. Therefore, it is important to teach children that fire is very dangerous, and that matches and lighters are not toys.

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Fire Escape Plans

Fires in the home can start in an instant and spread in seconds. Everyone in your family should know the fastest and safest way out of any room in your home.

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Types of Smoke Alarms

Every year, more than 3,000 people die in home fires in the United States. Fire deaths are usually the result of breathing in toxic smoke, and most fatal fires occur at night. 

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Home Fire Sprinklers

A house fire is reported every 60 seconds in the United States. Though many homeowners have smoke alarms, they are often not working, without batteries, or disabled.

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Fall Prevention

Falls are the most common cause of childhood injury in the home, leading to more than 1.3 million visits to the ER each year. Parents and caregivers should take steps to make their homes safer.

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Smoke Alarms

Working smoke alarms are essential for preventing injuries and deaths caused by house fires. By giving you more time to escape, smoke alarms can cut your risk of dying in a house fire by nearly half.

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Home Exercise Equipment

A study conducted by researchers at the Center for Injury Research and Policy at Nationwide Children's Hospital examined home exercise equipment-related injuries among children in the US.

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Window Falls

Every year, over 5,100 children younger than 18 years of age are treated in U.S. hospital emergency departments for injuries related to falls from windows.

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Household Cleaners

An estimated 267,269 children 5 years old or younger were treated in US emergency departments for household cleaning product-related injuries from 1990 to 2006.

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Falls

Falls can occur anywhere in the home, especially in areas with cluttered floors, low lighting or slippery surfaces. The most serious falls happen from great heights and onto hard surfaces.

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Recalled Toys

On average, more than two children’s products are recalled each week in the United States. Recalls on children’s products represent more than 40 percent of recalls in the U.S.

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Choking and Suffocation

Choking and suffocation happen when something blocks a person’s airway and prevents breathing. This is a leading cause of death among children.

Poison

Every year in the United States, there are over 2.4 million poison exposures. A poison is something that can make you sick if you eat, drink, touch, or breathe it. 

Sports and Recreation

Different sports and recreation activities have their own specific injury risks. These tips will help keep you safe before you play.

General

From safety on the farm to protecting against heat-related injuries, these general safety recommendations will help keep your family safe.

Burns

On average, 120,000 children younger than 21 are treated in hospital emergency departments for burn-related injuries each year.

Home Safety

Your home should feel like a safe place. Following these tips will help keep your family safe around the house.

Research Projects

Learn more about the research projects coming out of the Center for Injury Research and Policy.

Injury Topics

View our research on a wide range of topics spanning home safety, burns, poison, sports and recreation, and transportation.

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Gun Safety

Americans own almost 200 million guns. However, a gun in the home can be very dangerous, especially for children.

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Kelly Lab

The Kelly Lab's research is focused on improving the care of children born with congenital heart disease, with a particular interest in single ventricle heart disease. Our work is translational in nature, centered on the discovery, development and dissemination of new diagnostics and treatments for patients with single ventricle heart disease.

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Chiang Lab

The Chiang Lab is devoted to the design of tissue-engineered trachea for the management of complex long-segment airway defects. An ideal tracheal graft will allow for the replacement of diseased for absent tissue with a living construct capable of renewal and regeneration.

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Khalsa Lab Staff

Learn more about principal investigator Amrik Singh Khalsa, MD, and his dynamic team in the Khalsa Lab.

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Khalsa Lab

Under the direction of Amrik Singh Khalsa, MD, the Khalsa Lab focuses on reducing disparities and improving outcomes in obesity and its related co-morbidities through family-based prevention interventions.

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Lee Lab

Learn more about Dean A. Lee, MD, PhD, and the staff in the Lee Lab.

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CRISPR / Gene Editing Core

The team of experts available through the CRISPR/Gene Editing Core at Nationwide Children’s, in collaboration with The Ohio State University, provides investigators at both institutions with CRISPR/Gene Editing services with reasonable turnaround times and at affordable prices.

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Timothy Cripe Lab

Under the direction of Timothy Cripe, MD, PhD, the Cripe Lab focuses on developing and testing new, targeted therapies for pediatric solid tumors and translating those findings into clinical studies.

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Kararoudi Lab

Under the direction of Meisam Naeimi Kararoudi, DVM, PhD, the Kararoudi Lab aims to develop novel cancer immunotherapies through CRISPR-Cas9 genome editing and screening technology.

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Bakaletz Lab

The Bakaletz Lab, led by Lauren Bakaletz, PhD, has been funded for over 25 years to study the pathogenesis, prevention and treatment of diseases. The primary focus of the lab’s work has been to design and test vaccine candidates that can prevent and/or resolve otitis media, or middle ear infection, and exacerbations of chronic obstructive pulmonary disease (COPD).

Resources & Infrastructure

The Abigail Wexner Research Institute at Nationwide Children's Hospital has a wealth of resources available to our researchers to ensure they have the tools they need to continue our mission of enhancing the health of children by engaging in high quality, cutting-edge research according to the

Core Facilities

On-site basic, clinical and general core services offer the latest resources for cutting-edge research support at the Abigail Wexner Research Institute at Nationwide Children's Hospital.

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Biopathology Center Processing and Banking Core

The Processing and Banking Core provides biospecimen processing and banking services, utilizing the best technologies for current and future research.

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Kelleher Lab

The Kelleher Lab, led by Kelly J. Kelleher, MD, MPH, research focuses on improving policy for, and the practice of, pediatric care for high risk children adversely affected by poverty, violence, neglect, alcohol, drug use or mental disorders.

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Toy Safety

Some toys can lead to injuries. These injuries can be the result of a flaw in the product design but can also happen when the toy is used in a way that does not follow the manufacturers’ instructions.

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Drug-Related Poisoning

The cause of these poisonings has shifted over the past decade. Prescription drug-related poisonings now lead to more deaths and emergency department visits than illegal drugs.

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Home Safety Program

Most people think of their homes as one of the places they feel the safest. However, millions of children are unintentionally injured in the home every year.

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High Chair and Chair-Related Injuries

High chairs are a common sight in homes with young children. To keep kids safe at meal time, read the chair manufacturer’s instructions and follow these injury prevention tips.

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Child Passenger Safety

Car crashes are the #1 cause of death among children in the US. Depending on age, weight and height, children need to be in car seats, booster seats, or seat belts every time they are in the car.

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Baby Carriers

An average of one child aged 5 years and younger is treated in U.S. hospital emergency departments every two hours for a carrier-related injury.

Transportation

Motor vehicle crashes are one of the leading causes of injuries among adults and children in the United States. Every 15 minutes in the U.S. one person is killed and 66 are treated in an ER.

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Strollers

Although strollers are typically used to safely transport children, on average, one child aged 5 years and younger is treated in U.S. hospitals every 45 minutes for a stroller- related injury.

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Nursery Safety

The most important job for parents is to keep their child safe from harm. Because newborns will spend most of their time sleeping, parents need to make sure the nursery is a safe place. 

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Firework Safety

Every year, Americans enjoy the 4th of July by setting off firecrackers, bottle rockets and sparklers. However, the celebration often turns into tragedy with the improper use of fireworks.

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Playground Safety

Unfortunately more than 213,000 kids younger than 18 are treated in U.S. hospital emergency departments for playground-related injuries every year.

Meet Our Team

Learn more about director Gary Smith, MD, DrPH, and his team of principal investigators at the Center for Injury Research and Policy.

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Crerand Lab

The Crerand Lab studies psychosocial outcomes such as body image in children and adolescents with acquired and congenital medical conditions, including craniofacial conditions and differences of sex development. Learn more about principal investigator Canice E. Crerand, PhD, and her dynamic team in the Crerand Lab.