2022 Technology Showcase: Advancing Innovation Into the Marketplace

Each year, our Technology Showcase event highlights the novel and innovative discoveries, technologies and startup companies developed through research at Nationwide Children's and improving pediatric health. Thank you to our presenters and those who attended.

View the 2022 event recording above, and check out our past events page for additional recordings. Stay tuned for information about future events.

Agenda

Presentations

Thursday, March 3

BabySure
Lindsay Alfano will discuss democratizing access to early identification of infant movement disorders.

Presenter: Lindsay N. Alfano, PT, DPT, PCS
Principal Investigator, Center for Gene Therapy, Abigail Wexner Research Institute; Research Assistant Professor of Pediatrics, The Ohio State University.
Pioglitazone for the Reduction of Proteinuria in Childhood Nephrotic Syndrome
Michelle Higgin will discuss childhood nephrotic syndrome as a highly unmet rare disease treated for the last 60+ years by chronic steroid therapy. Now, Nephkey Therapeutics is repurposing an old metabolic drug that shows the same beneficial effects of steroid therapy without the associated immunosuppression and other toxicities.

Presenter: Michelle Higgin, PhD, NephKey
CEO, NephKey.
Targeting AAV Gene Therapy for White Matter Disorders
Allison Bradbury will discuss the development of a targeted AAV-mediated gene therapy approach for Vanishing White Matter disease.

Presenter: Allison Bradbury, MS, PhD
Principal Investigator, Center for Gene Therapy, Abigail Wexner Research Institute; Assistant Professor of Pediatrics, The Ohio State University.
Gene Therapy for CMT1B
Afrooz Rashnonejad will discuss the development of a new gene therapy approach to normalize MPZ protein levels in Schwann cells, which is expected to improve Charcot-Marie-Tooth type 1B (CMT1B) symptoms.

Presenter: Afrooz Rashnonejad, MSc, PhD
Post Doctoral Scientist, Center for Gene Therapy, Abigail Wexner Research Institute.
Tumor Assisted Delivery of Therapeutic Payloads
Kevin Cassady will discuss how our proposed tumor assisted delivery seeks to use naturally occurring extracellular vesicles (EVs) produced by tumors to selectively deliver therapeutics back to cancer cells.

Presenter: Kevin A. Cassady, MD
Physician, Division of Infectious Diseases, Nationwide Children’s Hospital; Principal Investigator, Center for Childhood Cancer and Blood Diseases, Abigail Wexner Research Institute; Associate Professor of Pediatrics, The Ohio State University College of Medicine.

Panel

Tune in for a panel discussion with gene therapy pioneers on insights gained, lessons learned and the region's growing gene therapy ecosystem.