Research Labs

Baker Lab

Under the direction of Linda Baker, MD, the Baker Lab studies the genetics of genitourinary congenital conditions, with a primary focus on Prune Belly Syndrome (PBS).

Becknell Lab

Under the direction of Michael Brian Becknell, MD, PhD, the Becknell Lab studies the mechanisms responsible for kidney injury and recovery in response to urinary tract obstruction and infection.

Ching Lab

Under the direction of Christina Ching, MD, the Ching Lab uses a mouse model of infection to understand the host response to urinary tract infection. In addition, the lab performs in vitro simulation of infection and collects human urine samples to look for differences in components of the urine in those individuals susceptible to infection.

Ruiz-Rosado Lab

Under the direction of Juan de Dios Ruiz-Rosado, PhD, the Ruiz-Rosado lab focuses on understanding the cellular immune mechanisms that contribute to the resistance or susceptibility to urinary tract infections, particularly acute pyelonephritis (APN), and the development of renal scarring following APN. 

Spencer Lab

Under the direction of John David Spencer, MD, the Spencer Lab focuses on the function and regulation of antimicrobial proteins in the Ribonuclease A Superfamily.

Zepeda-Orozco Lab

Under the direction of Diana Zepeda-Orozco, MD, MS, the Zepeda-Orozco Lab studies the implications of tubular epithelial cells mitochondrial metabolism and oxidative stress in acute kidney injury and chronic kidney disease progression.

Affiliate Labs

Kerlin Lab

Under the direction of Bryce Kerlin, MD, the Kerlin Lab aims to discover new approaches to prevent thrombotic complications and treat kidney disease.

Smoyer Lab

Under the direction of William E. Smoyer, MD, the Smoyer Lab focuses its research around three main themes of nephrotic syndrome, one of the most common kidney diseases seen in children.