Center for Childhood Cancer Research

The mission of the Center for Childhood Cancer Research is to expand the understanding of the pathogenesis of childhood cancer and to improve strategies for diagnosis and treatment.

Our areas of focus include:

  • Biology and therapy of rhabdomyosarcoma and other childhood tumors
  • Chemotherapy of childhood solid tumors
  • Regulation of alternative pre-mRNA splicing
  • Regulation and function of tumor suppressor genes
  • Oncolytic viral therapy in pediatric brain tumors
  • Immunotherapy and cellular therapies that harness the natural ability of the immune system to fight cancers
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The Abigail Wexner Research Institute is ranked among the top 10 for NIH funding among free-standing children's hospitals.

Inside our Zebrafish Facility: Genetic, Life-Saving Research

The Abigail Wexner Research Institute at Nationwide Children’s Hospital is home to our cutting-edge Zebrafish Facility. These tiny fish are used in multiple disciplines in thousands of laboratories around the world. Because Zebrafish are similar to humans, our researchers are able to use the system to study processes that are difficult or impossible to follow in other animals. The level of expertise and the state-of-the-art facility set us apart in this field. This research will bring hope to families and will help better treat children with life-threatening conditions and diseases. Come inside our facility and learn more about this genetic, life-saving research.

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For Trainees

Research Institute Training Association (RITA)

Trainee Association

The Research Institute’s Trainee Association (RITA) was created in 2013 to help better train and prepare trainees for their “next steps.”

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Life in Columbus

Vibrant neighborhoods. Unlimited arts and entertainment. Learn why Columbus, Ohio is a great place to live, work and play. 

Faculty Positions

Step inside the Center for Childhood Cancer Research, and you’ll find clinicians and researchers collaborating under the same roof to understand pediatric cancer, how it develops and how to treat it — all while mentoring and educating the next generation of scientists. This is a team that understands collaboration is key to ambitious basic science and impactful translational research. Thanks to that approach, its researchers are responsible for some of the most groundbreaking discoveries in pediatric cancer today.

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Career Opportunities

We have a purpose for every passion. Join our team and discover your passion for what’s possible in providing best outcomes for children.

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Research Positions at Nationwide Children's

Click here to view a list of our current openings at The Research Institute at Nationwide Children's Hospital.

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Life in Columbus

Vibrant neighborhoods. Unlimited arts and entertainment. Learn why Columbus, Ohio is a great place to live, work and play. 

For Patients & Families

Young smiling cancer patient wearing head wrap

Hematology, Oncology & Blood and Marrow Transplant

Our hematology, oncology, and blood and marrow transplant teams treat patients with all forms of cancer and blood disorders. Our specialists participate in collaborative research across the country and around the world to bring innovative treatments to our patients.

Nationwide Children's Hospital Lawn with Butterflies


When you light up the lawn, you brighten patients’ holidays, help us find cures and provide the world’s finest care.

Tissue sample from cancer patient

World-renowned Biopathology Center

The Biopathology Center at Nationwide Children’s Hospital serves as the only pediatric repository for pediatric solid tumor and is one of only two repositories for leukemia samples in the United States, Canada and Australia.