Center for Cardiovascular Research

The mission of the Center for Cardiovascular Research is to conduct innovative, mechanism-based research leading to improved therapies and outcomes for pediatric cardiovascular diseases and to foster preventive strategies and promote cardiovascular health in adults.

NIH Logo

The Abigail Wexner Research Institute is ranked among the top 10 for NIH funding among free-standing children's hospitals.

Our Areas of Focus

  • Cardiovascular Development
  • Congenital and Acquired Valve Disease
  • Vascular Disease and Homeostasis
  • Genetics of Congenital Heart Disease

Center Extramural Grant Funding

Investigator Title Sponsor Award Years
Mingtao Zhao
A pilot biorepository of patient-specific induced pluripotent stem cells for studying single ventricle heart defects
Additional Ventures Tools & Technology Expansion Award
2021 - 2022
Mingtao Zhao Maternal blood biomarker discovery for predicting ventricular growth in human fetuses with pulmonary atresia with intact ventricular septum (PA-IVS) Additional Ventures Innovation Fund 2021 - 2024
Mingtao Zhao
An integrated human stem cell model for elucidating NOTCH signaling in myocardial-endocardial interactions in cardiac development and disease
NIH/NHLBI
2020 - 2025
Kim McBride Functional consequences of FHC mutations in cardiac MyBPC Case Western Reserve University/ NIH 2020 - 2025
Mingtao Zhao Elucidating Mechanisms of Ventricular Hypoplasia in Pulmonary Atresia with Intact Ventricular Septum (PA-IVS) Using Patient-Derived Induced Pluripotent Stem Cells Additional Ventures Innovation Fund 2020 - 2022
Kim McBride Development of a Protocol to Risk Stratify Individuals with Single Ventricle Congenital Heart Disease Using Deep Phenotyping and Genome Sequencing Additional Ventures Innovation Fund 2020 - 2022
Kim McBride The Genetics of Cardiovascular Malformations: A Clinical Approach Indiana University/ AHA 2019 - 2022
Vidu Garg
Epigenetic Mechanisms Underlying Maternal Diabetes Associated Cardiac Malformations
NIH/NHLBI
2019 - 2023
Mingtao Zhao NOTCH Signaling in Human Vascular Development and CADASIL AHA 2018 - 2022
Aaron Trask Novel Non-Invasive Coronary Flow Patterning to Predict Early Coronary Microvascular Disease NIH/NIBIB 2018 - 2022
Madhumita Basu Mechanisms of Maternal Hyperglycemia Induced Risk of Congenital Heart Disease AHA 2018 - 2022
Brenda Lilly Mechanisms of Cardiac and Pulmonary Fibrosis in Relation to TGF-beta Signaling and miR-145 Function NIH/NHLBI 2017 - 2022
Kim McBride Center of Research Translation in Muscular Dystrophy Therapeutic Development - Muscular Dystrophy Cell and Serum Banking Core NIH/NIAMS 2016 - 2021

Trainees in the News

2021

Ruth Ackah, MD: The Ohio State University Center for Clinical and Translational Science Mentored Career Development Training Program Postdoctural Award

Sathiya Manivannan, PhD: American Heart Association and Children's Heart Foundation Congenital Heart Defect Research Awards Postdoctoral Fellowship

2020

Randaa Breikaa: North American Vascular Biology Organization (NAVBO) Vascular Biology 2020 Conference Outstanding Poster Award

Adrianna Matos-Nieves, PhD: The Ohio State University Molecular, Cellular and Developmental Biology inaugural Student Spotlight Award for Service and Engagement

Ruth Ackah, MD: The Ohio State University Department of Surgery 2020 James D. King MD, PhD Surgical Research Award

Training Links

Med Pros

Training in Congenital and Acquired Heart Disease

A five-year, $1.6 million training grant funds in-depth, interdisciplinary, translational and state-of-the-art research training in congenital and acquired heart disease to clinicians and basic scientists.

Female resident working in a research lab

Patient-Centered Pediatric Research Program

The Patient-Centered Pediatric Research Program prepares postdoctoral fellows to engage in independent outcomes research in child health settings and become leaders in the conduct of patient- and family-centered outcomes research.

Research Medical Fellows

Research Pathway

The Integrated Research Pathway is an American Board of Pediatrics  approved mechanism for pediatric residency training. Learn more about this program and the application process. 

Research Institute Training Association (RITA)

Trainee Association

The Research Institute’s Trainee Association (RITA) was created in 2013 to help better train and prepare trainees for their “next steps.”

Resident and Patient

Office of Trainee Affairs (OTA)

Research education and training is vital to the mission of the Abigail Wexner Research Institute (AWRI) at Nationwide Children's Hospital. As a top 10 free-standing pediatric research center and an academic affiliate of The Ohio State University, AWRI has an outstanding faculty dedicated to

Nationwide Children's Hospital Exterior

DISCOVERYx: The Stories Behind Discovery

Learn more about research and academic events going on at Nationwide Children's Hospital.

Career Opportunities

Med Pros

Join the Center for Cardiovascular Research Team

Click here to view a list of our current openings at the Center for Cardiovascular Research.

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Career Opportunities

We have a purpose for every passion. Join our team and discover your passion for what’s possible in providing best outcomes for children.

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Life in Columbus

Vibrant neighborhoods. Unlimited arts and entertainment. Learn why Columbus, Ohio is a great place to live, work and play. 

Inside the Center for Cardiovascular Research