Center for Cardiovascular Research
The mission of the Center for Cardiovascular Research is to conduct innovative, mechanism-based research leading to improved therapies and outcomes for pediatric cardiovascular diseases and to foster preventive strategies and promote cardiovascular health in adults.
Our Areas of Focus
- Cardiovascular Development
- Congenital and Acquired Valve Disease
- Vascular Disease and Homeostasis
- Genetics of Congenital Heart Disease
Center Extramural Grant Funding
|Joy Lincoln||Medical Therapies in the Treatment of Calcific Aortic Valve Disease||NIH/NHLBI||2018 - 2023|
|Emily Nordquist||The Ohio State T32 Training Grant for Predoctoral Students in Cardiovascular Research||NIH/NHLBI||2018 - 2021|
|Madhumita Basu||Mechanisms of Maternal Hyperglycemia Induced Risk of Congenital Heart Disease||AHA||2018 - 2021|
|Punashi Dutta||The Utilization of Nuclear Export Inhibitor Drugs to Treat Calcific Aortic Valve Disease||AHA||2018 - 2020|
|Sathiyanarayanan Manivannan||T32 Post-Doctoral Fellowship - Functional Evaluation of Novel, Rare Variants Associated with Infantile-Onset Cardiomyopathy and Hypoplastic Left Heart Syndrome||NIH/NHLBI||2018 - 2020|
|Kim McBride||Genetic Registry for Pediatric Heart Disease: The CCVM Consortium||Indiana University/ March of Dimes||2018 - 2019|
|Joy Lincoln (Co-I)||The Role of Rbfox2 in Hypoplastic Left Heart Syndrome||NIH/NHLBI||2017 - 2022|
|Brenda Lilly||Mechanisms of Cardiac and Pulmonary Fibrosis in Relation to TGF-beta Signaling and miR-145 Function||NIH/NHLBI||2017 - 2021|
|Joy Lincoln||Nationwide Children's Summer Undergraduate Research Program||AHA||2017 - 2020|
|Aaron Trask (Co-I)||The Role of a Serine Rich Repeat Protein Required for Binding Multiple Carbohydrates in Streptococcus oralis Endocarditis||AHA||2017 - 2019|
|Joy Lincoln, Vidu Garg, Brenda Lilly||The Role of Notch in Calcific Aortic Valve Disease||NIH/NHLBI||2016 - 2020|
|Aaron Trask||Differential Macro- and Micro-Vascular Remodeling in Type 2 Diabetes and Metabolic Syndrome||NIH/NHLBI||2016 - 2019|
|Vidu Garg, Joy Lincoln||Molecular Mechanisms of Aortic Valve Formation||NIH/NHLBI||2015 - 2019|
|Joy Lincoln||The Role of Sox-9 in Calcific Aortic Valve Disease||NIH/NHLBI||2015 - 2019|
A five-year, $1.6 million training grant was recently renewed to provide in-depth, interdisciplinary, translational and state-of-the-art research training in congenital and acquired heart disease to clinicians and basic scientists.
SURF provides undergraduates with the opportunity to perform clinical and basic science research within The Research Institute at Nationwide Children’s Hospital over the summer.
The Patient-Centered Pediatric Research Program prepares postdoctoral fellows to engage in independent outcomes research in child health settings and become leaders in the conduct of patient- and family-centered outcomes research.
The Integrated Research Pathway is an American Board of Pediatrics approved mechanism for pediatric residency training. Learn more about this program and the application process.
The Research Institute’s Trainee Association (RITA) was created in 2013 to help better train and prepare trainees for their “next steps.”
Research education and training are vital to the mission of Nationwide Children's Hospital and The Research Institute at Nationwide Children's Hospital.
Learn more about research and academic events going on at Nationwide Children's Hospital.
We have a purpose for every passion. Join our team and discover your passion for what’s possible in providing best outcomes for children.
Click here to view a list of our current openings at The Research Institute at Nationwide Children's Hospital.
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Inside the Center for Cardiovascular Research
Meet Our Team
Learn more about director Vidu Garg, MD, and his team of principal investigators at the Center for Cardiovascular Research.
Cardiovascular Research Shared Resource
The Cardiovascular Research Shared Resource is available to facilitate both basic and translational research for basic science and clinical faculty.
Under the direction of Vidu Garg, MD, The Garg Lab focuses on identifying the genetic contributors to congenital heart defects.
Under the direction of Brenda Lilly, PhD, the Lilly Lab is interested in the fundamentals of blood vessel formation and smooth muscle differentiation.
Under the direction of Joy Lincoln, PhD, the Lincoln Lab is focused on understanding the molecular mechanisms that regulate normal heart formation in the embryo.
Under the direction of Kim McBride, MD, MS, the McBride lab investigates the cause of congenital heart defects, with a focus on malformations involving the left side of the heart.
Under the direction of Patrick McConnell, MD, the McConnell’s Lab focuses on studying biological models of heart function, pathophysiology and cardiac assisting devices.