Center for Cardiovascular Research
The mission of the Center for Cardiovascular Research is to conduct innovative, mechanism-based research leading to improved therapies and outcomes for pediatric cardiovascular diseases and to foster preventive strategies and promote cardiovascular health in adults.
The Abigail Wexner Research Institute is ranked among the top 10 for NIH funding among free-standing children's hospitals.
Our Areas of Focus
- Cardiovascular Development
- Congenital and Acquired Valve Disease
- Vascular Disease and Homeostasis
- Genetics of Congenital Heart Disease
Center Extramural Grant Funding
Investigator | Title | Sponsor | Award Years |
Mingtao Zhao | Elucidating Mechanisms of Ventricular Hypoplasia in Pulmonary Atresia with Intact Ventricular Septum (PA-IVS) Using Patient-Derived Induced Pluripotent Stem Cells | Additional Ventures Innovation Fund | 2020 - 2022 |
Kim McBride | Development of a Protocol to Risk Stratify Individuals with Single Ventricle Congenital Heart Disease Using Deep Phenotyping and Genome Sequencing | Additional Ventures Innovation Fund | 2020 - 2022 |
Kim McBride | The Genetics of Cardiovascular Malformations: A Clinical Approach | Indiana University/ AHA | 2019 - 2022 |
Vidu Garg |
Epigenetic Mechanisms Underlying Maternal Diabetes Associated Cardiac Malformations |
NIH/NHLBI |
2019 - 2023 |
Mingtao Zhao | NOTCH Signaling in Human Vascular Development and CADASIL | AHA | 2018 - 2021 |
Aaron Trask | Novel Non-Invasive Coronary Flow Patterning to Predict Early Coronary Microvascular Disease | NIH/NIBIB | 2018 - 2021 |
Madhumita Basu | Mechanisms of Maternal Hyperglycemia Induced Risk of Congenital Heart Disease | AHA | 2018 - 2021 |
Sathiyanarayanan Manivannan | T32 Post-Doctoral Fellowship - Functional Evaluation of Novel, Rare Variants Associated with Infantile-Onset Cardiomyopathy and Hypoplastic Left Heart Syndrome | NIH/NHLBI | 2018 - 2020 |
Brenda Lilly | Mechanisms of Cardiac and Pulmonary Fibrosis in Relation to TGF-beta Signaling and miR-145 Function | NIH/NHLBI | 2017 - 2021 |
Kim McBride | Center of Research Translation in Muscular Dystrophy Therapeutic Development - Muscular Dystrophy Cell and Serum Banking Core | NIH/NIAMS | 2016 - 2021 |
Brenda Lilly, Vidu Garg | The Role of Notch in Calcific Aortic Valve Disease | NIH/NHLBI | 2016 - 2020 |
Aaron Trask | Differential Macro- and Micro-Vascular Remodeling in Type 2 Diabetes and Metabolic Syndrome | NIH/NHLBI | 2016 - 2020 |