Center for Cardiovascular Research
The mission of the Center for Cardiovascular Research is to conduct innovative, mechanism-based research leading to improved therapies and outcomes for pediatric cardiovascular diseases and to foster preventive strategies and promote cardiovascular health in adults.
The Abigail Wexner Research Institute is ranked among the top 10 for NIH funding among free-standing children's hospitals.
Our Areas of Focus
- Cardiovascular Development
- Congenital and Acquired Valve Disease
- Vascular Disease and Homeostasis
- Genetics of Congenital Heart Disease
Center Extramural Grant Funding
Investigator | Title | Sponsor | Award Years |
Mingtao Zhao |
A pilot biorepository of patient-specific induced pluripotent stem cells for studying single ventricle heart defects |
Additional Ventures Tools & Technology Expansion Award |
2021 - 2022 |
Mingtao Zhao | Maternal blood biomarker discovery for predicting ventricular growth in human fetuses with pulmonary atresia with intact ventricular septum (PA-IVS) | Additional Ventures Innovation Fund | 2021 - 2024 |
Mingtao Zhao |
An integrated human stem cell model for elucidating NOTCH signaling in myocardial-endocardial interactions in cardiac development and disease |
NIH/NHLBI |
2020 - 2025 |
Kim McBride | Functional consequences of FHC mutations in cardiac MyBPC | Case Western Reserve University/ NIH | 2020 - 2025 |
Mingtao Zhao | Elucidating Mechanisms of Ventricular Hypoplasia in Pulmonary Atresia with Intact Ventricular Septum (PA-IVS) Using Patient-Derived Induced Pluripotent Stem Cells | Additional Ventures Innovation Fund | 2020 - 2022 |
Kim McBride | Development of a Protocol to Risk Stratify Individuals with Single Ventricle Congenital Heart Disease Using Deep Phenotyping and Genome Sequencing | Additional Ventures Innovation Fund | 2020 - 2022 |
Kim McBride | The Genetics of Cardiovascular Malformations: A Clinical Approach | Indiana University/ AHA | 2019 - 2022 |
Vidu Garg |
Epigenetic Mechanisms Underlying Maternal Diabetes Associated Cardiac Malformations |
NIH/NHLBI |
2019 - 2023 |
Mingtao Zhao | NOTCH Signaling in Human Vascular Development and CADASIL | AHA | 2018 - 2022 |
Aaron Trask | Novel Non-Invasive Coronary Flow Patterning to Predict Early Coronary Microvascular Disease | NIH/NIBIB | 2018 - 2022 |
Madhumita Basu | Mechanisms of Maternal Hyperglycemia Induced Risk of Congenital Heart Disease | AHA | 2018 - 2022 |
Brenda Lilly | Mechanisms of Cardiac and Pulmonary Fibrosis in Relation to TGF-beta Signaling and miR-145 Function | NIH/NHLBI | 2017 - 2022 |
Kim McBride | Center of Research Translation in Muscular Dystrophy Therapeutic Development - Muscular Dystrophy Cell and Serum Banking Core | NIH/NIAMS | 2016 - 2021 |
Trainees in the News
2021
Ruth Ackah, MD: The Ohio State University Center for Clinical and Translational Science Mentored Career Development Training Program Postdoctural Award
Sathiya Manivannan, PhD: American Heart Association and Children's Heart Foundation Congenital Heart Defect Research Awards Postdoctoral Fellowship
2020
Randaa Breikaa: North American Vascular Biology Organization (NAVBO) Vascular Biology 2020 Conference Outstanding Poster Award
Adrianna Matos-Nieves, PhD: The Ohio State University Molecular, Cellular and Developmental Biology inaugural Student Spotlight Award for Service and Engagement
Ruth Ackah, MD: The Ohio State University Department of Surgery 2020 James D. King MD, PhD Surgical Research Award