Center for Cardiovascular Research

The mission of the Center for Cardiovascular Research is to conduct innovative, mechanism-based research leading to improved therapies and outcomes for pediatric cardiovascular diseases and to foster preventive strategies and promote cardiovascular health in adults.

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The Abigail Wexner Research Institute is ranked among the top 10 for NIH funding among free-standing children's hospitals.

Our Areas of Focus

  • Cardiovascular Development
  • Congenital and Acquired Valve Disease
  • Vascular Disease and Homeostasis
  • Genetics of Congenital Heart Disease

Center Extramural Grant Funding

Investigator Title Sponsor Award Years
Mingtao Zhao Maternal blood biomarker discovery for predicting ventricular growth in human fetuses with pulmonary atresia with intact ventricular septum (PA-IVS) Additional Ventures Innovation Fund 2021 - 2023
Sathiyanarayanan Manivannan Developmental origins of HLHS examined using genetically-linked RBFOX2 variant AHA 2021 - 2022
Kim McBride Functional consequences of FHC mutations in cardiac MyBPC Case Western Reserve University/ NIH 2020 - 2025
Mingtao Zhao Elucidating Mechanisms of Ventricular Hypoplasia in Pulmonary Atresia with Intact Ventricular Septum (PA-IVS) Using Patient-Derived Induced Pluripotent Stem Cells Additional Ventures Innovation Fund 2020 - 2022
Kim McBride Development of a Protocol to Risk Stratify Individuals with Single Ventricle Congenital Heart Disease Using Deep Phenotyping and Genome Sequencing Additional Ventures Innovation Fund 2020 - 2022
Kim McBride The Genetics of Cardiovascular Malformations: A Clinical Approach Indiana University/ AHA 2019 - 2022
Vidu Garg
Epigenetic Mechanisms Underlying Maternal Diabetes Associated Cardiac Malformations
2019 - 2023
Mingtao Zhao NOTCH Signaling in Human Vascular Development and CADASIL AHA 2018 - 2021
Aaron Trask Novel Non-Invasive Coronary Flow Patterning to Predict Early Coronary Microvascular Disease NIH/NIBIB 2018 - 2021
Madhumita Basu Mechanisms of Maternal Hyperglycemia Induced Risk of Congenital Heart Disease AHA 2018 - 2021
Brenda Lilly Mechanisms of Cardiac and Pulmonary Fibrosis in Relation to TGF-beta Signaling and miR-145 Function NIH/NHLBI 2017 - 2021
Kim McBride Center of Research Translation in Muscular Dystrophy Therapeutic Development - Muscular Dystrophy Cell and Serum Banking Core NIH/NIAMS 2016 - 2021
Brenda Lilly, Vidu Garg The Role of Notch in Calcific Aortic Valve Disease NIH/NHLBI 2016 - 2020
Aaron Trask Differential Macro- and Micro-Vascular Remodeling in Type 2 Diabetes and Metabolic Syndrome NIH/NHLBI 2016 - 2020

Training Links

Med Pros

Training in Congenital and Acquired Heart Disease

A five-year, $1.6 million training grant funds in-depth, interdisciplinary, translational and state-of-the-art research training in congenital and acquired heart disease to clinicians and basic scientists.

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Patient-Centered Pediatric Research Program

The Patient-Centered Pediatric Research Program prepares postdoctoral fellows to engage in independent outcomes research in child health settings and become leaders in the conduct of patient- and family-centered outcomes research.

Research Medical Fellows

Research Pathway

The Integrated Research Pathway is an American Board of Pediatrics  approved mechanism for pediatric residency training. Learn more about this program and the application process. 

Research Institute Training Association (RITA)

Trainee Association

The Research Institute’s Trainee Association (RITA) was created in 2013 to help better train and prepare trainees for their “next steps.”

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Office of Trainee Affairs (OTA)

Research education and training is vital to the mission of the Abigail Wexner Research Institute (AWRI) at Nationwide Children's Hospital. As a top 10 free-standing pediatric research center and an academic affiliate of The Ohio State University, AWRI has an outstanding faculty dedicated to

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Research and Academic Events

Learn more about research and academic events going on at Nationwide Children's Hospital.

Career Opportunities

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Career Opportunities

We have a purpose for every passion. Join our team and discover your passion for what’s possible in providing best outcomes for children.

Med Pros

Research Positions at Nationwide Children's

Click here to view a list of our current openings at The Research Institute at Nationwide Children's Hospital.

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Life in Columbus

Vibrant neighborhoods. Unlimited arts and entertainment. Learn why Columbus, Ohio is a great place to live, work and play. 

Inside the Center for Cardiovascular Research