Heart Clinical Research

Through The Heart Center at Nationwide Children’s Hospital and the Center for Cardiovascular and Pulmonary Research at The Research Institute, clinicians and scientists work together to match questions developed at the bedside with answers found in the lab. These collaborative endeavors then deliver improvements to treatment options, all in the name of enhancing patient care. This approach ensures that patients receive the latest advances in cardiac care at Nationwide Children’s Hospital.

To see current research studies related to Cardiology being conducted at Nationwide Children's Hospital and The Ohio State University, search the options below.

Dairy Study Seeking Overweight Adults 18-50 Years Old

Why are we doing this study?

Researchers in the Human Nutrition Program at The Ohio State University are doing this study to discover how dairy milk can help regulate blood glucose responses and improve cardiovascular (heart) health.

Who can participate in this study?

You may be eligible for this study if you are:

  • A man OR woman between the ages of 18-50 years old

  • At least 20 pounds overweight (BMI greater than 25)

  • A non-smoker

  • Not allergic to dairy milk or do not have any aversions to dairy milk

You are NOT eligible for this study if you:

  • Have allergies or aversions to dairy milk

  • Are pregnant or breastfeeding

  • Consume more than 3 alcoholic drinks per day

  • Exercise aerobically more than 7 hours per week

  • Take any medications to manage high cholesterol, inflammation or metabolism

  • Have a history of cardiovascular disease or gastrointestinal disorders

What will happen during this study?

There is no cost for taking part in this study, and participants will be compensated up to $400 for completing the study. The cost of parking will also be provided.

For more information, please email OSUDairy2015@gmail.com or call 614-292-1698 from 8 a.m. to  5 p.m., Monday through Friday.

Egg Nutrition Study Seeking Overweight Men Ages 18-50

What is purpose of this study?

The purpose of this study is to understand how eggs can help regulate blood glucose responses and improve cardiovascular health in men.

Who can participate in this study?

  • Men, aged 18-50 years old

  • At least 20 pounds overweight (BMI > 25)

  • Non-smoker

  • Do not have allergies or aversions to eggs

  • Do not take any medications to manage high cholesterol, inflammation or metabolism

  • Do not have a history of cardiovascular disease or gastrointestinal disorders

  • Do not consume more than 3 alcoholic drinks per day

  • Do not exercise aerobically more than 7 hours per week

What will happen during the study?

If you are eligible for this study and choose to participate, you will visit our study center for four visits, each separated by at least a week. During these visits you will be fed a meal, and then we will draw blood and assess arterial function every thirty minutes, for three hours.

This study will have 4 study visits over 4-6 weeks and will take place at Campbell Hall at The Ohio State University. There is no cost for taking part in this study, and participants will be compensated up to $300 for completing the study. Cost of parking will also be provided.

Who can I contact for more information?

If you have questions or would like to take part in this study, please email OSUeggs@gmail.com or call 614-292-1698 from 8AM to 5PM, Monday through Friday.

Sudden Cardiac Death in Duchenne Muscular Dystrophy and Becker Muscular Dystrophy: Incidence and Prevention Patient Registry

What is the purpose of the study?

This study is a registry for patients with Duchenne Muscular Dystrophy (DMD). Patients with DMD develop cardiomyopathy, or weakening of the heart muscle, and heart failure as the disease progresses. Some patients will experience sudden cardiac death (SCD). Researchers want to find out what the risk of SCD is in patients with DMD. Researchers also want to find out if having an implantable cardioverter-defibrillator (ICD) will benefit patients by preventing SCD related to abnormal heartbeats. They also would like to know if patients with ICD’s suffer complications from the device.

Who can participate in the study?

This study is for patients who are at least 10 years old, have Duchenne Muscular Dystrophy or Becker Muscular Dystrophy, and have a weak heart (ejection fraction less than 55%) or a heart device (for example, a pacemaker or ICD).

What will happen during the study?

During this study, we will collect information about your health from your medical records and record it in an electronic database.

Who can I contact if I am interested or if I have any questions?

If you feel you may be eligible, please call 614-722-0494 or contact the study coordinator, Susan Meyer at Susan.Meyer@NationwideChildrens.org. You may also download the study flyer here.

Genetics of Congenital Heart Disease

What is the purpose of this study?

We are currently conducting research to identify genes important for causing congenital heart defects in children. It is our hope that the identification of these genes will lead to new ways to prevent or treat congenital heart disease.

What can participate? 

All patients with congenital heart disease are eligible although the current focus is on families with multiple affected members.

What will happen during the study?

The study requires the collection of a blood sample either in the clinic or at the time of heart surgery or cardiac catheterization.

Who can I contact for more information?

Jade Hayden, Clinical Research RN
(614) 355-5648

ClinicalTrials.gov
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