Pediatric Surgery Clinical Research

Clinical researchers at Nationwide Children's are committed to identifying new approaches for the prevention, diagnosis and treatment of childhood diseases, taking research discoveries from the lab to the patient's bedside.

To see current Pediatric Surgery research studies being conducted at Nationwide Children's Hospital, search the options below.

A Comparison: High Intense Periodic vs. Every Week Therapy in Children With Cerebral Palsy (ACHIEVE)

Researchers at Nationwide Children’s Hospital and Ohio State University are seeking volunteers to participate in a pediatric physical therapy treatment study for children with gross motor delays to find out the most effective service delivery of rehabilitation.

Your child may be eligible for this study if you or your child meets the following criteria:

  • Is between 2 and 8 years of age

  • Diagnosis of motor delay or CP in GMFCS levels I- V

  • Is able to participate in outpatient physical therapy and attend visits consistently

  • Parent/Caregiver agrees to participate in long-term follow up

Your child will receive a total of 40 hours of physical therapy delivered in either 1 hour or 2 hour sessions depending on group assignment, along with 9 monthly physical therapy consultations and 4 assessments. All participants will be compensated for study participation. Parking will be covered for everyone.

For more information, please contact the ACHIEVE study team, let by Dr. Jill Heathcock, at 614-572-5446, or email ACHIEVE@osumc.edu.

Study ID: IRB16-00492

A prospective, double-blinded, randomized comparison of caudal analgesia versus ultrasound guided rectus sheath blocks for umbilical herniorrhaphy in the pediatric population

Purpose of study:

The purpose of this study is to prospectively compare post-operative pain relief in pediatric patients undergoing umbilical hernia repair who have received either a caudal block or bilateral rectus sheath blocks for analgesia.

Who can participate:

ASA physical status I or II
Weight less than or equal to 20 kg
Presenting for repair of umbilical hernia

What will happen during the study:

This study is a prospective, double-blinded, randomized comparison of 2 patient cohorts. One group of patients will receive a caudal epidural block. The second group will receive bilateral rectus sheath blocks for umbilical hernia repair.

Who to contact:

Study Staff: (614) 580-2828 or (614) 722-0742
Leah.Nishimura@NationwideChildrens.org

Help Researchers Learn About the Relationship Between Breast Milk and Necrotizing Enterocolitis

What’s the purpose of the study?

Researchers at Nationwide Children’s Hospital are studying the components of breast milk to see if it prevents or has an impact on the effects of necrotizing enterocolitis, a disease of the intestines that can cause babies to become critically ill.

Who can take part in this study?

You can participate if you are:

  • Between the ages of 18 and 40
  • Currently pregnant or delivered a baby in the last 4 months

What will happen during the study?

Participants will be asked to donate a minimum of 2 teaspoons (10 mL) of breast milk every week for as long as they are willing and able. Donation tubes will be provided.

Will we be paid for the study?

Yes. Participants will receive $5 per sample donated. 

For more information or to enroll, call Nitin Sajankila at (732) 343-2400 or email Nitin.Sajankila@NationwideChildrens.org

Principal Investigator: Gail E. Besner, MD 

Randomized Controlled Trial of Laser Hair Depilation in the Treatment of Pilonidal Disease

Purpose of the study:

A number of studies have found that laser hair removal greatly reduces the recurrence rate of pilonidal disease. Drs. Minneci and Deans, pediatric surgeons at Nationwide Children’s Hospital, are currently conducting a study that will help better understand how laser hair removal can help patients with pilonidal disease.

Eligibility criteria:

  • Ages 11 - 21 years old
  • Diagnosis of pilonidal disease

What will happen during the study:

Participants of the study will be assigned to receive laser hair removal or standard care. All participants will be followed through 1 year of treatment, with follow-up occurring, at 1, 2, 3, 4, 5, 6, 9, and 12 months after enrollment.

Who to contact:

If you would like to participate in a clinical trial for laser hair removal please contact us at (614) 580-2828, (614) 722-0742 or email Leah.Nishimura@NationwideChildrens.org.
TAP vs. Local Anesthetic for Lap Appendectomies

Purpose of study:

The purpose of this study is to prospectively compare post-operative pain relief in pediatric patients undergoing laparoscopic appendectomy who have received either a transversus abdominis plane (TAP) block or local anesthetic infiltration by the surgeon for analgesia.

Who can participate:

Inclusion criteria:

  • ASA physical status I or II
  • Weight less than or equal to 60 kg
  • Presenting for laparoscopic appendectomy

What will happen during the study:

We will compare the pain management of a child undergoing laparascopic appendectomy by using a transverse abdominis plane block which is local anesthetic injected by the anesthesiologist using an ultrasound machine versus a surgeon injecting local anesthetic at the site of incision.

Who to contact:

NDiris Barry (SAM)
Department of Anesthesiology

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