Besner Lab
The Besner Lab at Nationwide Children’s aims to eliminate necrotizing enterocolitis (NEC) and its downstream consequences.
Britt Lab
The Britt Lab studies how inflammation affects airway structure and function in asthma, cystic fibrosis, and bronchopulmonary dysplasia. Their goal is to define physiological and immunological mechanisms that drive chronic airway disease, while also developing novel strategies that can alleviate disease and improve airway function.
Chen Lab
The Chen Lab examines pathways involved in vascular remodeling and smooth muscle cell proliferation, the pathogenic hallmarks of PH. Its research is focused on the phosphodiesterase 3 (PDE3) pathway and the distinct function and activity of each isoform (PDE3A and PDE3B) and their mechanistic interaction with the nitric oxide (NO)-cGMP pathway, which remain largely unknown.
Liu Lab
The Liu Lab studies inflammation, immunity, sepsis and more using both animals and cells.
Lynch Lab
Under the direction of Thomas Lynch, PhD, the Lynch Lab leverages cutting-edge animal models, cell and tissue culture techniques, and transcriptomics to study region-specific cell differentiation, renewal and regenerative plasticity in the conducting airways of the lung.
Nelin Lab
The Nelin Lab’s focus is on inflammatory lung injury and the mechanisms leading to lung diseases, particularly bronchopulmonary dysplasia (BPD).
Reynolds Lab
The main focus of the Reynolds Lab involves elucidating the mechanisms involved in airway epithelial tissue repair using mouse models and human cell cultures to pave the way for the eventual use of human tissue stem cell therapy to treat cystic fibrosis and other forms of chronic lung disease.
Slaughter Lab
The Slaughter Lab aims to improve outcomes important to neonatal patients and their families through large patient-focused cohort investigations and randomized trials.