Core Facilities

The Animal Resources Core (ARC) assists with animal health and study support, animal acquisition and transport, training and husbandry and housing. The Abigail Wexner Research Institute is committed to ensuring the humane care of the animals utilized for research and teaching. The ARC balances compassionate animal care with research needs to deliver the highest quality service and discovery in pediatric research.

The Biobehavioral Outcomes Core assists investigators who want to incorporate behavioral assessments in their research.

Biologics Manufacturing maintains facilities, equipment and personnel for manufacturing a wide range of cellular therapeutic products for clinical trials including natural killer (NK) cells, CAR NK and CAR T cells and a tissue engineered vascular graft.

The Processing and Banking Core provides biospecimen processing and banking services, utilizing the best technologies for current and future research.

The Cell Line Core processes human subject samples and provides the researcher with cell lines or DNA, appropriate for downstream applications in a variety of human and molecular genetic studies.

The Steve and Cindy Rasmussen Institute for Genomic Medicine (IGM) Clinical Laboratory at Nationwide Children’s Hospital provides a variety of cytogenetic and molecular genetic tests for genetic conditions and cancers.

Clinical Research Services (CRS) is a portal through which clinical investigators access streamlined coordination of services necessary to initiate clinical research projects, regardless of funding source.

The Ohio State University Clinical and Translational Science Institute (CTSI) is a collaboration among the University, The Ohio State University Wexner Medical Center and Nationwide Children's Hospital dedicated to turning the scientific discoveries of today into life-changing disease prevention strategies and the health diagnostics and treatments of tomorrow.

The “big data” nature of genome-based clinical tests and research studies requires advanced high-performance computing and bioinformatics platforms to rapidly analyze and interpret information.

The team of experts available through the CRISPR/Gene Editing Core at Nationwide Children’s, in collaboration with The Ohio State University, provides investigators at both institutions with CRISPR/Gene Editing services with reasonable turnaround times and at affordable prices.

The DNA Sequencing Core uses ABI dye terminator sequencing technologies for routine sequencing of plasmid and PCR templates.

The Flow Cytometry Core lab offers several platforms on which to do flow analysis and/or cell sorting. 

The goal of the iPSC Core is to generate and share iPSC lines with investigators not only at Nationwide Children's and The Ohio State University, but throughout Ohio and across the country.

The Histopathology Core provides exceptional services to internal investigators, including laboratory procedures in histology, electron microscopy and Atomic Force microscopy.

The Microscopy Core provides training, consultation and advanced support for optical microscopy and image analysis to investigators throughout Nationwide Children’s Hospital.

Technology and applications development is an essential component of the Steve and Cindy Rasmussen Institute for Genomic Medicine's vision.