Henry Xiang Team
Henry Xiang, MD, MPH, PhD, MBA
Principal Investigator
Dr. Henry Xiang is an internationally recognized physician-scientist and clinical translational science expert whose work bridges population health, medicine and digital innovation. He is professor of medicine and epidemiology at The Ohio State University, co-director of the Pilot Translational and Clinical Studies Program at the NIH-funded Clinical and Translational Science Institute, and director of the Center for Pediatric Trauma Research and director of research at the Center for Injury Research and Policy at Nationwide Children’s Hospital.
Dr. Xiang’s research focuses on injury and violence prevention, trauma outcomes, disability and rehabilitation, and acute and chronic pain, with particular emphasis on causal inference, data science, artificial intelligence and medical extended reality. He is internationally known for pioneering triplet and poly-matching causal-inference frameworks for evaluating multi-arm interventions in trauma care and public health, as well as for leading clinical trials of digital extended reality for pediatric pain management, anxiety, and brain-injury rehabilitation.
His work has informed national and global policy, including contributions to the U.S. Department of Health and Human Services’ Healthy People 2020 Disability and Health objectives, the World Health Organization’s World Report on Disability, and the development of NIH pediatric injury research priorities that informed creation of NICHD's Pediatric Trauma and Critical Illness Branch. He has held numerous national and international leadership roles, including president of the Society for Advancement of Violence and Injury Research (SAVIR) and founder and inaugural president of the Global Association for Pediatric Extended Reality.
Dr. Xiang has received more than 56 externally funded grants from NIH, CDC, AHRQ, HRSA, WHO and other agencies, and has authored nearly 300 peer-reviewed publications. His honors include awards from German Medical Association, American Public Health Association, SAVIR, and HIMSS North America. In 2025, Dr. Xiang was elected an inaugural fellow of both SAVIR and the American Medical Extended Reality Association.
Funded by NIH/Eunice Kennedy Shiver National Institute of Child Health and Human Development, this R01 study aims to use innovative causal inference statistical methods to assess outcomes of major medical procedures for acute treatment of moderate to severe traumatic brain injury.
Agency for Healthcare Research and Quality funded this multi-site R01 study to determine VR-PAT effectiveness for pain management and opioid medication use reduction during at-home burn care and to identify potential facilitators and barriers that could affect wide use of VR-PAT.
This pilot study is a randomized crossover clinical trial to assess the safety, feasibility, and efficacy of VR-PAT for pain management during outpatient laser procedures and to assess sex, age, and anxiety as key factors.
Team Members
Megan Armstrong, MPH
Clinical Research Coordinator Team Lead
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Megan earned a B.S. in human nutrition and community health in 2012 and a Master of Public Health in 2015 from The Ohio State University. After receiving her MPH, Megan worked as a contractor at the Centers for Disease Control and Prevention (CDC) assisting with the Ebola response and the Division of Global Health Protection. Since joining Dr. Xiang’s team in 2018, her research interests include improving treatment and outcomes following pediatric traumatic injuries, including burns and traumatic brain injuries. In her free time, Megan enjoys spending time with her husband, son, and two dogs and cheering for the Buckeyes!
Biche Osong, PhD
Post-Doctoral Scientist
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Biche Osong is a Big Data enthusiast with a demonstrated ability to translate the available data generated across the continuum of care into knowledge for strategic and personalized decision-making via peer-reviewed journal articles. His work mostly involves working with experts to help answer domain-specific questions using (interpretable) AI or statistical techniques. Since joining Dr. Xiang’s team as a post-doctoral scientist, his research interest has shifted from oncology to trauma & injury, but he enjoys collaborating with people in different research fields. Research aside, Biche is a family man and a Real Madrid FC supporter.
Hannah Williams, MPH
Research Associate
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Hannah earned a B.S. in biology from Purdue University in 2022 and a Master of Public Health in sociomedical sciences with a certificate in child, youth, and family health from Columbia University in 2024. As a graduate student researcher at Columbia Mailman School of Public Health, she worked alongside a team on an NICHD study investigating K-12 school gun violence and school safety strategies. She is continuing her work in child health and injury and violence prevention, expanding into the clinical research space, and growing as a scientist as a Research Associate alongside Dr. Xiang and his team. Outside of research, Hannah loves spending time with her partner and their Italian Greyhound, cheering on the Purdue Boilermakers, and attending concerts of her favorite artists.