Other/Multiple Specialties

These trials involve finding solutions for patients who have more than one condition involving hematology, oncology, & bone and marrow transplant. Multispecialty studies focus on new ways to treat the whole patient through by studying the correlations between different diseases.

CHOP HAdV: Outcomes of Human Adenovirus (HAdV) Infection and Disease in Pediatric Allogeneic Stem Cell Transplant Recipients: A Prospective Multicenter Observational Cohort

Protocol ID: CHOP HAdV

Disease: Adenovirus

Who can participate?: Age less than 18 years of age at the time of transplant.

Lead Researcher: Monica I. Ardura

ISTH Database and DNA Biorespository for Congenital Antithrombin Deficiency- pilot/feasibility study

Protocol ID: ISTH Database

Disease: 122

Who can participate?: Ages 0-21 years; AT deficiency confirmed

Lead Researcher: Amy L. Dunn

Neuropsychological, Social, Emotional, and Behavioral Outcomes in Children with Cancer

Protocol ID: ALTE07C1

Disease: Multiple

Who can participate?: The patient must currently be enrolled or plan to be enrolled on a COG therapeutic study that aims to examine neuropsychological, social, emotional, and/or behavioral functioning.

Lead Researcher: Mark A. Ranalli

Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections

Protocol ID: DOMINIC

Who Can Participate?: Ages 3 months to 21 years

Lead Researcher: Monica I. Ardura, DO, MSCS

Phase 1/1b Open Label Dose Escalation and Expansion study of Entrectinib (RXDX-101) in Children and Adolescents with recurrent or refractory solid tumors and primary CNS tumors, with or without TRK, ROS1, and ALK fusions

Protocol ID: RXDX-101

Disease: CNS/Solid Tumors

Who can participate?: Ages vary with patient cohorts- see protocol

Lead Researcher: Mohamed Shebl AbdelBaki

Testicular tissue cryopreservation for fertility preservation in male patients facing infertility-causing diseases or treatment regimens

Protocol ID: Testicular Cryo

Who Can Participate?: Ages 0 to 99

Lead Researcher: Nicholas D. Yeager, MD

The Project: Every child Protocol: A Registry, Eligibility Screening, Biology and Outcome Study

Protocol ID: APEC14B1

Disease: All Cancer

Who can participate?: Subjects must be ≤ 25 years of age at time of original diagnosis, except for patients who are being screened specifically for eligibility onto a COG (or COG participating NCTN) therapeutic study, for whom there is a higher upper age limit.

Lead Researcher: Mark A. Ranalli, MD

Umbrella Long-Term Follow-Up Protocol

Protocol ID: ALTE05N1

Disease: Multiple

Who can participate?: The patient must be enrolled on a frontline COG therapeutic trial for treatment of a primary malignancy and is nearing completion of or has recently completed protocol treatment (within the past 180 days)*; or the patient must have been enrolled on a COG (or Legacy Group) therapeutic or non-therapeutic trial targeted for long-term follow-up by ALTE05N1.

Lead Researcher: Mark A. Ranalli