Germ Cell Cancers

Germ cell tumors are masses that form from reproductive cells. Most germ cell tumors that are cancerous occur usually occur in the form of testicular cancer or ovarian cancer, although they can be found in other parts of the body as well.

Our clinical trials focus on combination chemotherapy, high-dosage chemotherapy to better understand the safest and most effective way to combat germ cell cancers. There are also clinical trials that aim to better identify germ cell tumors to avoid the return of tumors after treatment. In addition, some clinical trials for germ cell tumors focus on quality of life by reducing symptoms and side effects.

A Phase 3 Study of Active Surveillance for Low Risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors

Protocol ID: AGCT1531

Disease: GCT

Who can participate?:

"Low Risk Stratum: Patients must be < 50 years of age at enrollment.

Standard Risk 1: Patient must be < 11 years of age at enrollment.

Standard Risk 2: Patients must be ≥ 11 and < 25 years of age at enrollment"

Lead Researcher: Mark A. Ranalli, MD