How Vincristine Works in Babies
Phase: Recruiting
Condition(s): Cancer
NCT Number: NCT05359237 Other Study ID Number(s): PEPN22P1
What Is the Purpose of This Study?
This pilot trial compares drug exposure levels using a new method for dosing vincristine in infants and young children compared to the standard dosing method based on body surface area (BSA) in older children.
Who Can Take Part in This Study?
- Patients must be =< 12 years of age at the time of study enrollment.
- Newly diagnosed and relapsed cancer diagnosis that is being treated with vincristine at the 1.5 mg/m^2 dose level.
What Will Happen During This Study?
- Patients will receive vincristine IV per the standard of care (SOC).
- Patients will undergo collection of blood samples at baseline (before first vincristine dose), and 2, 6-8, and 18-24 hours after a dose of vincristine.
- Patients may also undergo collection of blood samples with a second SOC vincristine dose at the same time points.
Principal Investigator
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