Blood Biomarkers for Detecting Minimal Residual Disease in Pediatric Sarcomas

Phase: Recruiting

Condition(s): Sarcoma

Other Study ID Number(s): MCC20320

What Is the Purpose of This Study?

To see if detecting cell-free plasma tumor DNA (ptDNA) and circulating tumor cells (CTC) can predict recurrence of disease in patients who are in radiographic remission 2-3 weeks after treatment. Plasma tumor DNA (ptDNA) is free floating DNA from the tumor found in the blood stream and circulating tumor cells.

Who Can Take Part in This Study?

People who may be eligible for this study:

  • Have a new sarcoma diagnosis.
  • Are ages 0 to 40 years.

What Will Happen During This Study?

Patients will undergo blood sample collection throughout the study. Timepoints of collection will depend on if local control is delayed or up front. Results from these blood draws will not be returned to the PI or the patient.

Principal Investigator

Bhuvana A. Setty
MD

Hematology & Oncology

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