Study of ctDNA to Predict Outcomes in New Cases of Ewing Sarcoma or Osteosarcoma
Phase: Recruiting
Condition(s): Ewing Sarcoma, Osteosarcoma
NCT Number: NCT06068075 Other Study ID Number(s): ctDNA
What Is the Purpose of This Study?
This study evaluates whether circulating tumor deoxyribonucleic acid (ctDNA) in the blood can provide information about the chances of Ewing sarcoma or osteosarcoma coming back after treatment and locate specific genetic alterations.
Who Can Take Part in This Study?
People who may be eligible for this study:
- Are 12 months old at time of study enrollment to 50 years old.
- Have histologic diagnosis (by institutional pathologist) of newly diagnosed, localized or regionally disseminated Ewing sarcoma or peripheral primitive neuroectodermal tumor (PNET) of bone or soft tissue.
- Or have histologic diagnosis (by institutional pathologist) of newly diagnosed, non-pelvic, localized or regionally disseminated high-grade osteosarcoma.
What Will Happen During This Study?
PART A: Patients undergo blood sample collection throughout the study. Physicians and patients do not receive any return of results of the ctDNA analysis on study.
PART B: Patients undergo blood sample collection during follow-up. Physicians receive ctDNA return of results and discuss results with patients/parents. Patients/parents and providers complete surveys prior to receipt of first ctDNA return of results and after discussion of ctDNA return of results.
Principal Investigator
Discover More Research
Explore additional studies relating to sarcoma and solid tumorsYour Might Also Be Interested In
Exploring Pediatric Clinical Research
Clinical research involves the study of people, data or tissue samples to understand children’s health and diseases. It’s the foundation for medical advancement and plays a large role in improving health outcomes for children, teenagers and families.
Clinical Research: How We Keep Volunteers Safe
Clinical research is a type of research that involves people. Research participants help researchers to study new types of treatments, like new medicines or medical devices. It might even include changes in how people live or act, such as different ways to eat or exercise.
Stay Updated With Clinical Research. Follow @NCHClinicalResearch on Instagram!
Parents and caregivers can learn more about clinical research on our Instagram channel, @NCHClinicalResearch. You can be part of the clinical research that moves us forward in our journey to best outcomes for all children, everywhere.