Key Adverse Events after Childhood Cancer
Phase: Recruiting
Condition(s): Cancer
NCT Number: NCT00082745 Other Study ID Number(s): ALTE03N1
What Is the Purpose of This Study?
This clinical trial studies cancer survivors to identify those who are at increased risk of developing late-occurring complications after undergoing treatment for childhood cancer.
Who Can Take Part in This Study?
People who may be eligible for this study:
- Diagnosis of primary cancer at age 21 or younger
- Development of one of the following key adverse events at any time following initiation of cancer therapy: Cardiac dysfunction; please note: case enrollment has been closed due to achievement of target accrual
- Ischemic stroke (IS)
- Subsequent malignant neoplasm (SMN)
- Avascular necrosis (AVN); please note: case enrollment has been closed due to achievement of target accrual
What Will Happen During This Study?
DNA from peripheral blood or saliva sample from patients will be analyzed for the presence of variations in genes associated with an increased risk of late-occurring complications.