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Hematology, Oncology, BMT Clinical Studies

Nationwide Children's Hematology/Oncology/BMT is committed to advancing both basic and clinical research. The division maintains active membership in the Children’s Oncology Group and the Pediatric Blood and Marrow Transplant Consortium, and is a research member of the International Blood and Marrow Transplant Registry. The division is also involved in other clinical research efforts aimed at improving bone marrow transplant outcomes. Hematology, Oncology and Blood and Marrow Transplant works hand-in-hand with the Center for Childhood Cancer and Blood Diseases to expand the understanding of childhood cancer and to improve strategies for its diagnosis and treatment.

Approximately 74 percent of eligible oncology patients are enrolled in clinical trials at Nationwide Children’s Hospital, making the division one of the leading cancer centers for clinical trial enrollment by the Children’s Oncology Group.

ACNS0822 A Randomized Phase II/III Study of Children with Newly Diagnosed High-Grade Gliomas

ARST08P1 (Pilot 2) A Pilot Study to Evaluate Novel Agent Temozolomide in Combination with Intensive Multi-Agent Interval Compressed Therapy for Patients with High-Risk Rhabdomyosarcoma

AEWS1031: A Phase III Randomized Trial for Initial Treatment of Non-metastatic Ewing Sarcoma

ACNS0332 Efficacy of Carboplatin Administered Concomitantly With Radiation and Isotretinoin as a Pro-Apoptotic Agent in Other Than Average Risk Medulloblastoma/PNET Patients

ACNS0334 A Phase III Randomized Trial for the Treatment of Newly Diagnosed Supratentorial PNET and High Risk Medulloblastoma in Children< 36 Months Old

ACNS0831 Phase III Randomized Trial of Post-Radiation Chemotherapy in Patients with Newly Diagnosed Ependymoma Ages 1 to 21 years

ACNS0821 Randomized Phase II Screening Trial for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood

European Ewing Tumour Working Initiative of National Groups Ewing Tumour Studies 1999 (EURO-E.W.I.N.G.99)

ARAR0332 Treatment of Adrenocortical Tumors with Surgery plus Lymph Node Dissection and Multiagent Chemotherapy

ARST0531 Randomized Study for Patients with Intermediate-Risk Rhabdomyosarcoma (RMS)

ARST0921 A Randomized Phase II Trial of Bevacizumab (Avastin) and Temsirolimus (Torisel) in Patients with Recurrent/Refractory Rhabdomyosarcoma

AALL0932 Treatment of Patients with Newly Diagnosed Standard Risk B-Lymphoblastic Leukemia (B-ALL) or Localized B-lineage Lymphoblastic Lymphoma (B-LLy)

ARST08P1 (Pilot 2) A Pilot Study to Evaluate Novel Agent Temozolomide in Combination with Intensive Multi-Agent Interval Compressed Therapy for Patients with High-Risk Rhabdomyosarcoma

Treatment for Steroid Resistent Acute Graft Versus Host Disease

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000