Wedemeyer Lab Staff

Michelle A. Wedemeyer, MD, PhD
Principal Investigator
Michelle.Wedemeyer@NationwideChildrens.org

Michelle A. Wedemeyer, MD, PhD, is a pediatric neurosurgeon at Nationwide Children's Hospital, the principal investigator of a basic science laboratory in the Institute for Genomic Medicine at Nationwide Children's Hospital, and an assistant professor of Neurosurgery at The Ohio State University College of Medicine. Her clinical and research interests are focused on the interplay of developmental neurobiology and pediatric neurosurgical diseases including brain tumors, vascular malformations, and hydrocephalus. Ongoing projects in the lab include the creation of a single nuclei multiomic analysis of the developing human brain, single cell investigations of common disease processes in the pediatric neurosurgical populations, a longitudinal investigation of the effects of radiation on the growing pediatric brain, and the development of liquid biopsy genomic assays for brain vascular malformations. Overall, the laboratory seeks to apply state of the art genomics technologies to better understand common neurosurgical disease processes in children and improve the overall neurosurgical care for the children in our community.

Gary Schweickart
Bioinformatics Analyst
Gary.Schweickart@NationwideChildrens.org

Gary Schweickart is a bioinformatics analyst in the Wedemeyer Lab. His current work centers on the analysis of cellular diversity of pediatric brain tumors and the characterization of the developing hindbrain to identify novel targets for pediatric brain tumors at the single-cell level using R, python, and Linux. Gary earned his bachelor's degree from Miami University, where he studied Mathematics and Statistics.

Nicholas Marchal
Research Associate 
Nicholas.Marchal@nationwidechildrens.org

Nick is an undergraduate student working in the Wedemeyer Lab. His work focuses on using rodent and cell models to understand how key genetic mutations in Diffuse Midline Gliomas contribute to its pathogenesis, specifically through their inhibitory effect on axon myelination in the developing brain. He is pursuing a bachelor's of science in biomedical science with a minor in pharmaceutical sciences and a certificate in clinical trials sciences at The Ohio State University, where he expects to graduate in Spring 2026 with hopes to attend medical school in the future.