Stanton Lab: Systems Epigenetics Group
We’re a highly collaborative group, focusing on epigenetics and genomics. We investigate fundamental modes of gene regulation and how they can be disrupted in human disease.
We are motivated to understand chromatin structure in the context of epigenetic activation and repression, as we define projects at the interface of epigenomics and pediatric cancer biology. Our view is that understanding basic epigenetic mechanisms and vulnerabilities will provide the groundwork for precision therapies.
Inside Stanton Lab
Our Research
Understanding Epigenetic Regulation in Childhood Cancer
Nucleosomes are the most fundamental unit of DNA packaging in eukaryotes and, therefore, the most fundamental subunit of epigenetics studies. Since nucleosomes are segments of wrapped DNA that resemble yarn wrapped around a spool, these hand-crocheted models made of yarn by Dr. Emma Chory, a post-doctoral fellow at Massachusetts Institute of Technology, are an extremely fitting way to showcase what our researchers examine in their work!
Epigenomics for Chromatin Architecture
In order to define altered epigenetic states, our group develops new methods for understanding chromatin structure, and how proteins bind to the genome. Our methods are driven by questions connecting chromatin remodeling and genome architecture.
We’re recruiting! The Stanton Lab is looking for motivated, curious and dedicated postdocs and graduate students. Feel free to reach out to us!
