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Computational Genomics

The “big data” nature of genome-based clinical tests and research studies requires advanced high-performance computing and bioinformatics platforms to rapidly analyze and interpret information.

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Genomic Services

The Genomics Services Laboratory has extensive expertise in multiple aspects of genomics analysis.

New Initiative Aims to Improve Diagnosis and Treatment of Children with Solid Tumors Through Molecular Analysis
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New Initiative Aims to Improve Diagnosis and Treatment of Children with Solid Tumors Through Molecular Analysis

The National Cancer Institute (NCI), part of the National Institutes of Health, Children’s Oncology Group (COG), and Nationwide Children's Hospital are poised to change the direction of pediatric cancer diagnosis and care. New results from international efforts to characterize pediatric cancers have led to the Molecular Characterization Initiative: a project that aims to collect, analyze, and report clinical molecular data to support COG-affiliated clinicians in choosing the best treatment for each child. This program is part of the NCI Childhood Cancer Data Initiative (CCDI).

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1 Year In, the CCDI Molecular Characterization Initiative Has Analyzed Samples From Over 1,000 Patients

The CCDI Molecular Characterization Initiative (MCI) is a project that aims to collect, analyze and report clinical and molecular data and is currently supporting Children’s Oncology Group (COG)-affiliated clinicians in choosing the best treatment for each child through precision diagnosis. This program is part of the National Cancer Institute (NCI) Childhood Cancer Data Initiative (CCDI), a national commitment and community-wide effort to harness data in ways that speed up progress in childhood cancer. Announced last year, the MCI is a collaboration among NCI, part of the National Institutes of Health, COG and Nationwide Children’s Hospital and is the largest initiative of its kind in the United States.

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Kloczkowski Lab

Andrzej Kloczkowski, PhD's research lab interests focus on various aspects of computational molecular biology and structural bioinformatics.

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Nationwide Children’s Hospital Announces the Steve and Cindy Rasmussen Institute for Genomic Medicine

Nationwide Children’s Hospital announced today that its nationally known genomic medicine institute is being renamed to honor the transformational support of Steve and Cindy Rasmussen.

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Clinical Laboratory

The Steve and Cindy Rasmussen Institute for Genomic Medicine (IGM) Clinical Laboratory at Nationwide Children’s Hospital provides a variety of cytogenetic and molecular genetic tests for genetic conditions and cancers.

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Lauber Lab

The Lauber Lab examines how microbes affect health. Maturation of the microbiome in children is important for maintaining healthy host-microbe interactions throughout life.

Article

Das Lab

Jayajit Das, PhD's lab uses theoretical and computational approaches based on statistical physics to uncover basic mechanistic principles underlying our innate and adaptive immune response.

Genomic Medicine, Physician Dedication Give Family Answers About Teen’s Rare Disease
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Genomic Medicine, Physician Dedication Give Family Answers About Teen’s Rare Disease

Through whole exome sequencing performed in 2020 at the Steve and Cindy Rasmussen Institute for Genomic Medicine at Nationwide Children’s, one family was finally able to put a real name to their adolescent's rare disease.

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