Shah Lab

Dr. Shah’s laboratory investigates methods to develop off-the-shelf, universally compatible, scalable long-term hematopoietic stem cells (HSCs) for the treatment of blood and bone marrow cancers.

Dr. Shah’s laboratory uses state-of-the-art organ-in-a-dish, bio-inspired micro-electric-mechanical system (MEMS) fabrication, 4D-bioprinting, bio-inspired matrices,  3D organoid development, gene-editing, microfluidics, cell-engineering, nanotechnology, ex vivo mouse embryo and explant culture, as well as computational approaches. His laboratory also has expertise in utilizing zebrafish, mice, and human iPS cells to clone and analyze novel genes and mechanisms important for HSC biology and its use in improved cellular therapies.