Meet Our Child Neurology Residents & Fellows

Stephanie Ahrens, DO - Child Neurology, 3rd Year

  • Residency: Nationwide Children's Hospital Pediatrics Residency, Columbus, OH

  • Medical School: Des Moines University College of Osteopathic Medicine, Des Moines, IA

  • Awards:

    • American Academy of Neurology (AAN) 2016 Safety and Quality Award

  • Publications:

    • Ahrens S, Ostendorf A. First Episode of Hemiplegic Migraine. Pediatr Neurol 2017.

    • Ahrens S. Optimization of pre-hospital treatment of pediatric seizures: a quality improvement initiative. Presented at Safety and Quality Seminar at AAN, Vancouver CA, March 2016. 

    • Saker A, Athman S, Aldosari M, Frayha H. Encephalopathy and Axonal Neuropathy Associated with Mycolasma Pneumoniae Infection. Child Neurology Open. 2016; doi: 10.1177/2329048X16632140

    • Athman, S., Storey, K., Bendel, C.  Genotypic Analysis of Candida albicans strains isolated from neonates on a NICU: epidemic or coincidence? Poster presentation at American Academy of Pediatrics 2006 National Conference, Atlanta GA, September 2006. 

Daniel Freedman, DO - Child Neurology, 3rd Year

  • Residency: Nationwide Children's Hospital Pediatrics Residency, Columbus, OH

  • Medical School:  University of North Texas Health Science Center - Texas College of Osteopathic Medicine, Ft. Worth, TX

  • Publications:

    • Perry M.S., Bailey L., Freedman D., Donahue D., Malik S., Head H., Keator C., Hernandez A. (2017). Coregistration of multimodal imaging is associated with favourable two-year seizure outcome after paediatric epilepsy surgery. Epileptic Disorders, 19 (2017), 40-48.
    • Freedman D., Koram A., Gillson N., Aylward S. Pediatric PRES with spinal cord involvement due to pheochromocytoma. Pediatric Neurology, 77 (2017), 92-93.
    • Freedman D., Albert D. (2017). Neurology Education at U.S. Osteopathic Medical Schools. Neurology, Resident and Fellow Section, 89 (2017), e282-e283.
    • Freedman D., Patel A. Inadequate Regulation Contributes to Mislabeled Online Cannabidiol Products. Pediatric Neurology Briefs, 32 (2018), 3.
    • Freedman D. Book Review: Neurology Image-Based Clinical Review. Journal of Child Neurology, October 23, 2018.
    • Freedman D. Letter to the Editor: Pharmacy Board Acted to Protect Consumers. Columbus Dispatch. September 16, 2018.
    • Freedman D, Koram A, Gillson N, Aylward SC. Pediatric Posterior Reversible Encephalopathy Syndrome (PRES) With Spinal Cord Involvement Due to Pheochromocytoma. Pediatr Neurol 2017.
  • Presentations:

    • Freedman D, Koram A, Gillson N, Aylward S. Pediatric PRES with Spinal Cord Involvement Due to Pheochromocytoma. Presented at:  American Academy of Neurology (AAN); Annual Meeting; 2016 April 15-21. Vancouver, BC.

Allie Kornbluh, MD - Child Neurology, 2nd Year

  • Residency: Nationwide Children's Hospital Pediatrics Residency, Columbus, OH

  • Medical School:  Johns Hopkins School of Medicine, Baltimore, MD

  • Publications:

    • Kornbluh, A. and Twanow, J. Adolescent Wallenberg's syndrome with overlooked signs: ipsipulsion and ipsilateral facial palsy. Accepted 2018, in press. 
    • Tanner, J., Rao, K., Salas, R. M., Strowd, R., Nguyen, A., Kornbluh, A., Mead-Brewer, E., Gamaldo, C. (2016). Engaging Medical Students in Neurology Clinic Improves Clinic Productivity and Cultivates an Optimal Educational Environment (S3.003). Neurology, 86(16 Supplement).
    • Kornbluh, Alexandra. Letter to the editor. “Bicycle Helmets Prevent Tragedy”. The Columbus Dispatch. 15 Feb 2016. 

Melissa Squires, MD, MPH - Child Neurology, 2nd Year

  • Residency: Nationwide Children's Hospital Pediatrics Residency, Columbus, OH

  • Medical School:  University of Rochester School of Medicine, Rochester, NY 

  • Publications:

    • Kellogg KM, Hettinger Z, Shah M, Wears RL, Sellers CR, Squires M, Fairbanks RJ. Our current approach to root cause analysis: is it contributing to our failure to improve patient safety? BMJ Qual Saf 2016;0:1–7. doi:10.1136/bmjqs-2016-005991. 

    • Fairbanks, RJ., Squires, M., Nobay, F., Grams, K.. Participation Rates and Emergency medicine provider perceptions of an Error Reporting System with User-Centered Design. Academic Emergency Medicine.2009 Apr; 16(4): 69. Pub Status: Published.

    • Nobay, F., Squires, M., Fairbanks RJ.,. Faculty Participation and Perceptions in a Novel Human Factors Directed Resident Evaluation Tool. Academic Emergency Medicine.2009 Apr; 16(4): 27. Pub Status: Published. 

    • Squires, M. (2007, October 12). Sarah Dolley- Woman Pioneer. Epitaph Magazine: Pub Status: Published.

Whitney Woodhull, MD – Child Neurology, 1st Year

  • Residency: Nationwide Children's Hospital Pediatrics Residency, Columbus, OH

  • Medical School:  Charles E. Schmidt College of Medicine at Florida Atlantic University

  • Publications:

    • Cunningham RM, Ranney M, Newton M, Woodhull W, Zimmerman M, Walton MA.. Characteristics of youth seeking emergency care for assault injuries.. Pediatrics. 2014, Jan; 133(1): 96-105.

Lisa Pabst, MD – Child Neurology, 1st Year

  • Residency: Nationwide Children's Hospital Pediatrics Residency, Columbus, OH

  • Medical School:  University of Texas Medical School at Houston

  • Publications:

    • Early outcomes in youth with psychogenic nonsyncopal collapse Geoffrey L. Heyer, Lisa M. Pabst, Brady N. Kaucic, Tionna A. Coley Neurology Aug 2018, 91 (9) e850-e858; DOI: 10.1212/WNL.0000000000006098
    • Bellance, N.V., Pabst, L.M., Allen, G.I., Rossignol, R., Nagrath, D.. Oncosecretomics coupled to bioenergetics identifies alpha-amino adipic acid, isoleucine and GABA as potential biomarkers of cancer: Differential expression of c-Myc, Oct1, and KLF4 coordinates metabolic change. Biochem Biophys Acta. 2012, Nov; 1817(11): 2060-2071.

    • Caneba, C.A., Bellance, N.V., Yang, L., Pabst, L.M., Nagrath, D.. Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration. Am J Physiol Endocrinol Metab. 2012, Oct; 303(8): 1036-1052.

    • Stence NV, Pabst LL, Hollatz AL, et al. Predicting Progression of Intracranial Arteriopathies in Childhood Stroke With Vessel Wall Imaging. Stroke 2017;48:2274-2277.

Matthew Martin, MD – Child Neurology, 1st Year

  • Residency: Nationwide Children’s Hospital Pediatric Residency, Columbus, OH

  • Medical School:  Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina

  • Publications:

    • Martin, MJ, Cartwright MS. A pilot study of strain elastography in the diagnosis of carpal tunnel syndrome. Journal of Clinical Neurophysiology. 2017, Mar;34(2):114-118.
    • Martin, M.J., Smelser, A.M., Holzwarth, G.. Dividing organelle tracks into Brownian and motor-driven intervals by variational maximization of the Bayesian evidence. European Biophysics Journal. 2016 Apr;45(3):269-77.

Daniel Clark, MD, PhD – Pediatrics, 2nd Year

  • Residency: Nationwide Children's Hospital Pediatrics Residency, Columbus, OH

  • Medical School:  The Ohio State University College of Medicine, Columbus, Ohio

  • Publications:

    • Akli KU, Hansen SB, Kemp AJ, Freeman RR, Beg FN, Clark DJ, Chen SD, Hey D, Hatchett SP, Highbarger K, Giraldez E, Green JS, Gregori G, Lancaster KL, Ma T, MacKinnon AJ, Norreys P, Patel N, Pasley J, Shearer C, Stephens RB, Stoeckl C, Storm M, Theobald W,. Laser heating of solid matter by light-pressure-driven shocks at ultrarelativistic intensities. Physical Review Letters. 2008, Apr; 100(16): 165002.

    • Clark, D.J., Smith, A.K., Dortch, R.D., Knopp, M.V., Smith, S.A.. Investigating hydroxyl chemical exchange using a variable saturation power chemical exchange saturation transfer (vCEST) method at 3 T. Magnetic Resonance in Medicine. 2016, Sep; 76(3): 826-837.

    • Jia G, Takayama Y, Flanigan DC, Kaeding CC, Zhou J, Chaudhari A, Clark DJ,Sammet S, Liang J, Choi S, Knopp MV. Quantitative assessment of mobile protein levels in human knee synovial fluid: feasibility of chemical exchange saturation transfer (proteinCEST) MRI of osteoarthritis. Magnetic Resonance Imaging. 2011, Apr; 29(3): 335-341.

    • Menendez, M.I., Clark, D.J., Carlton, M., Flanigan, D.C.., Jia, G., Sammet, S., Weisbrode, S.E., Knopp, M.V., and Bertone, A.L.. Direct delayed human adenoviral BMP-2 or BMP-6 gene therapy for bone and cartilage regeneration in a pony osteochondral model. Osteoarthritis and Cartilage. 2011, Aug; 19(8): 1066-1075.

    • Nguyen HT, Jia G, Shah ZK, Pohar K, Mortazavi A, Zynger DL, Wei L, Yang X, Clark DJ, Knopp MV. Prediction of chemotherapeutic response in bladder cancer using K-means clustering of dynamic contrast-enhanced (DCE)-MRI pharmacokinetic parameters. Journal of Magnetic Resonance Imaging. 2015, May; 41(5): 1374-1382.

    • Nguyen HT, Pohar KS, Jia G, Shah ZK, Mortazavi A, Zynger DL, Wei L, Clark DJ, Yang X, Knopp MV. Improving bladder cancer imaging using 3-T functional dynamic contrast-enhanced magnetic resonance imaging. Investigative Radiology. 2014, Jun; 49(6): 390-395.

    • Wu C, Mikhail S, Wei L, Timmers C, Tahiri S, Neal A, Walker J, El-Dika S, Blazer M, Rock J, Clark DJ, Yang X, Chen JL, Liu J, Knopp MV, Bekaii-Saab T. A phase II and pharmacodynamic study of sunitinib in relapsed/refractory oesophageal and gastro-oesophageal cancers. British Journal of Cancer. 2015, Jul; 113(2): 220-225.

Franziska Hoche, MD, PhD – Pediatrics, 1st Year

  • Residency: Nationwide Children's Hospital Pediatrics Residency, Columbus, OH

  • Medical School:  Goethe-University, Frankfurt, Germany

  • Publications:

    • Hoche F, Seidel K, Brunt ER, Auburger G, Schöls L, Bürk K, de Vos RA, den Dunnen W, Bechmann I, Egensperger R, von Broeckhoven C, Gierga K, Deller T, Rüb U. Involvement of the auditory brainstem system in spinocerebellar ataxia type 2 (SCA2), type 3 (SCA3) and type 7 (SCA7). Neuropathol Appl Neurobiol 2008;34:479-491[*]

    • Kieslich M, Hoche F, Reichenbach J, Weidauer S, Porto L, Vlaho S, Schubert R, Zielen S. Extracerebellar MRI lesions in Ataxia Telangiectasia go along with the GH-IGF-1 Axis, markedly reduced body weight, high ataxia scores and advanced age. Cerebellum 2010, 9: 190-197

    • Hoche F, Balikó L, den Dunnen W, Steinecker K, Bartos L, Sáfrány E, Auburger G, Deller T, Korf W, Klockgether T, Rüb U, Melegh B. Spinocerebellar ataxia type 2 (SCA2): Identification of early brain degeneration in one monozygous twin in the initial stage. Cerebellum 2011; 10(2): 245-253[*]

    • Hoche F, Pfeifenbring S, Vlaho S, Qirshi M, Theis M, Schneider W, Porto L, Müller K, Kieslich M. Rare brain biopsy findings in a first ADEM-like event of pediatric MS: histopathologic, neuroradiologic and clinical features. J Neural Transm 2011; 118:1311-7

    • Hoche F, Seidel K, Theis M, Vlaho S, Schubert R, Zielen S, Kieslich M. Neurodegeneration in Ataxia Telangiectasia. What is new? What is evident? Neuroped 2012, 43(3): 119-129

    • Hoche F, Qirshi M, Heidegger T, Kang JS, Koenig R, Kieslich M. Description of a novel c.374 G>A mutation in Becker disease. Muscle Nerve. 2013 Apr;47(4):616-7. doi: 10.1002/mus.23698. Epub 2013 Mar 4.

    • Rüb U1, Farrag K, Seidel K, Brunt ER, Heinsen H, Bürk K, Melegh B, von Gall C, Auburger G, Bohl J, Korf HW, Hoche F*, den Dunnen W*. Involvement of the cholinergic basal forebrain nuclei in spinocerebellar ataxia type 2 (SCA2). Neuropathol Appl Neurobiol 2013 Jan 30. doi: 10.1111/nan.12025.  *(joint senior author)

    • Hoche F*, Rüb U*, Brunt ER, Heinsen H, Seidel K, Auburger G, Del Turco D, Paulson HL, Bohl J, Vonsattel JP, von Gall C, Korf HW , den Dunnen WF. Degeneration of the cerebellum in Huntington’s disease (HD): Possible relevance for the clinical picture and potential gateway to pathological mechanisms of the disease process. Brain Pathol. 2013 Mar;23(2):165-77. doi: 10.1111/j.1750-3639.2012.00629.x. Epub 2012 Sep 21.*(joint first author)

    • Voss S, Pietzner J, Hoche F, Taylor AM, Last JI, Schubert R, Zielen S. Growth retardation and growth hormone deficiency in patients with Ataxia telangiectasia. Growth Factors. 2014 Jun;32(3-4):123-9. doi: 10.3109/08977194.2014.939805. 

    • Hoche F,  Frankenberg E, Rambow J, Theis M, Harding JA, Qirshi M, Seidel K, Barbosa-Sicard E, Porto L, Schmahmann JD, Kieslich M. Cognitive phenotype in ataxia-telangiectasia. Pediatr Neurol. 2014 Sep;51(3):297-310. doi: 10.1016/j.pediatrneurol.2014.04.027. Epub 2014 May 5.

    • Hoche F, Seidel K, Barbosa-Sicard E, Heidegger T, Kang JS, Koenig R, Kieslich M. Novel N-terminal truncating CLCN1 mutation in severe Becker disease. Muscle Nerve. 2014 Nov;50(5):866-7. doi: 10.1002/mus.24312. Epub 2014 Sep 24. 

    • Güell X, Hoche F, Schmahmann JD. Metalinguistic deficits in patients with cerebellar dysfunction:  empirical support for the dysmetria of thought theory. Cerebellum 2015 Feb;14(1):50-8. doi: 10.1007/s12311-014-0630-z.

    • Hoche F, Güell X, Vangel MG, Sherman J, Schmahmann JD. The cerebellar contribution to social cognition. Cerebellum 2015 Nov (19). Epub ahead of print

    • Hoche F, Harvey WP, Kieslich M. Cerebellar contribution to cognitive development in childhood with specific consideration of Ataxia-telangiectasia (AT). Neuropaediatrie in Klinik und Praxis 2016 (3); 1-6 [Abstract English, Manuscript German]

    • Hoche F, Güell X, Vangel MG, Sherman J, Schmahmann JD. Cerebellar cognitive affective syndrome / Schmahmann syndrome Rating Scale (Brain 4/2017, submitted, under review)

Brianna Noelle Brun, MD – Pediatrics, 1st Year

  • Residency: Nationwide Children’s Hospital Pediatric Residency, Columbus, Ohio
  • Medical School: University of Iowa Roy J. and Lucille A. Carver College of Medicine

  • Publications:

    • Brun, B.N., Mockler, S.R., Laubscher, K.M., Stephan, C.M., Collison, J.A., Zimmerman, M.B., Mathews, K.D.. Childhood Activity on Progression in Limb Girdle Muscular Dystrophy 2I. Journal of Child Neurology. 2017, Feb; 32(2): 204-209. Cited in PubMed; PMID: 27872178. Pub Status: Published.

    • Brun, B.N., Mockler, S.R., Laubscher, K.M., Stephan, C.M., Wallace, A.M., Collison, J.A., Zimmerman, M.B., Dobyns, W.B., Mathews, K.D.. Comparison of brain MRI findings with language and motor function in the dystroglycanopathies. Neurology. 2017, Feb; 88(7): 623-629. Cited in PubMed; PMID: 28087826. Pub Status: Published.

Megan Marie Fredwall, MD – Pediatrics, 1st Year

  • Residency: Nationwide Children’s Hospital Pediatric Residency, Columbus, Ohio
  • Medical School: University of Southern Carolina School of Medicine, Greenville

  • Publications:

    • Fredwall, M., Sternburg, S., Blackhurst, D., Lee, A., Leacock, R., & Nathaniel, T.. Gender Differences in Exclusion Criteria for Recombinant Tissue-Type Plasminogen Activator. Journal of Stroke and Cerebrovascular Diseases. 2016, Nov; 25(11): 2569–2574. Cited in PubMed; PMID: 27618196. Pub Status: Published.

    • Nathaniel, T. I., Cochran, T., Chaves, J., Fulmer, E., Sosa, C., Yi, S., Fredwall, M., Sternberg, S., Blackhurst, D., Nelson, A., & Leacock, R.. Co-morbid Conditions in Use of Recombinant Tissue Plasminogen Activator (rt-PA) for the Treatment of Acute Ischaemic Stroke. Brain Injury. 2016, Aug; 30(10): 1261-1265. Cited in PubMed; PMID: 27484159. Pub Status: Published.

Rae Leonor Ferrer Gumayan, MD – Pediatrics, 1st Year

  • Residency: Nationwide Children’s Hospital Pediatric Residency, Columbus, Ohio
  • Medical School: Southern Illinois University

Neurology Resident Retreat
Residents at a Recent Neurology Resident Retreat