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News
Human MicroRNA Inhibits Expression of Pathogenic Gene Underlying Facioscapulohumeral Muscular Dystrophy
Facioscapulohumeral muscular dystrophy (FSHD) is caused by aberrant expression of the DUX4 gene in skeletal muscles. Researchers at Nationwide Children’s Hospital have recently demonstrated that an endogenous human microRNA, miR-675, inhibits DUX4 expression and protects muscles from DUX4-mediated cell death in a mouse model when administered via gene therapy. They also showed that the small molecule-based treatments that upregulate miR-675 inhibited DUX4 mRNA and DUX4-associated biomarkers in myotubes derived from patients with FSHD.
Blog
The Poison Plants of Summer: Poison Ivy, Oak and Sumac
Summer is in full swing. You know the signs. Dad fires up the grill, mom finds her green thumb, your kids fetch their ball in the weeds…and the whole family comes down with an itchy rash. That’s right, the poison plants are back.
News
Depression During Pregnancy Increases Risk for Preterm Birth and Low Birth Weight
Note to Editor: Jeffrey Bridge, MD, an investigator in the Center for Innovation in Pediatric Practice in The Research Institute at Nationwide Children's Hospital, was a co-author of this study on maternal depression.
Article
Gunn Lab Staff
Learn more about principal investigator John Gunn, PhD, and his dynamic team in the Gunn Lab.
News
GenomeNext, Powered by Amazon Web Services and Intel, Achieves Unprecedented Throughput of 1,000 Genomes Analyzed per Day, Enabling Population-Scale Genomics
GenomeNext, LLC, a leader in genomic data management and integrated analysis, announced today that, through the “Intel Heads In The Clouds Challenge on Amazon Web Services (AWS)” with support from JHC Technology, and in conjunction with Nationwide Children’s Hospital, has
Article
Dietary Supplements & Young Athletes
Young athletes have a very high energy demand based on their need for growth, development, overall health, and activity level. Many athletes struggle to meet their nutritional needs and often turn to supplements to help fill this gap.
Article
Baker Lab
Under the direction of Linda Baker, MD, the Baker Lab studies the genetics of genitourinary congenital conditions, with a primary focus on Prune Belly Syndrome (PBS).
Specialty
Pharmacy Services
Our Pharmacy is committed to ensuring the right child receives the right medication in the right dose by the right route at the right time. The Orange, Blue and Yellow pharmacies prepare and dispense prescriptions for patients and staff.
Specialty
Adolescent and Young Adult (AYA) Oncology Program
Our Adolescent and Young Adult Program provides help and a network of individuals to support our AYA oncology patients in the areas of fertility, education, insurance, and social and emotional support.