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Early Phase Gene Therapy Study for SMARD1/CMT2S Disease Now Enrolling

Nationwide Children's Hospital has launched a new Phase I/IIa gene replacement clinical study to evaluate the safety of a gene therapy for IGHMBP2-related diseases, specifically spinal muscular atrophy with respiratory distress type 1 (SMARD1) and Charcot Marie Tooth disease type 2S (CMT2S). SMARD1 and CMT2S are rare inherited conditions that are both caused by mutations in the IGHMBP2 gene, of which more than 60 have been found to date. SMARD1 is the most severe form of these diseases and causes muscle weakness and respiratory failure in infancy.

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Nationwide Children's Researchers Work to Transform Approach to Epigenetic Studies in Pediatric Cancer

Researchers from the Center for Childhood Cancer Research at Nationwide Children’s Hospital offer a new platform technology and proof of concept that illuminates the role of PAX3::FOXO1, a known gene fusion driving rhabdomyosarcoma.

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Nationwide Children’s Hospital - Toledo Commits Over $100 Million Investment in New Outpatient Facilities to Expand Local Pediatric Care in Northwest Ohio

Nationwide Children’s Hospital - Toledo announced today a planned $100 to $150 million investment to expand pediatric care across the Toledo region over the next five years. The investment will support the construction of two new, state-of-the-art pediatric medical facilities designed to maximize patient safety and experience, enhance care and create capacity to recruit additional providers so children in northwest Ohio can receive more care close to home.

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Nationwide Children’s Hospital and Big Lots Announce 2022 Recipient of Big Lots Behavioral Health Scholarship

Christy Chacko, a graduate student at the University of Southern California, is the 2022 recipient of the Big Lots Behavioral Health Scholarship—a scholarship made possible by Nationwide Children’s Hospital and Big Lots, an Ohio-based home discount retailer.

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Abercrombie & Fitch Co. Pledges Financial Support for Nationwide Children's Hospital's Behavioral Health Initiatives

Abercrombie & Fitch Co. announced today that it has pledged $15 million over a period of six years to Nationwide Children’s Hospital and The Kids Mental Health Foundation to support behavioral health initiatives for children and young adults in central Ohio and across the country.

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Nationwide Children's Hospital to Expand Mental and Behavioral Health Research

Nationwide Children's Hospital has created a new Institute for Mental and Behavioral Health Research, significantly expanding opportunities to seek a better understanding of mental and behavioral health in children and to develop better diagnostics, treatment and preventative strategies. Leading this new institute will be Eric Youngstrom, PhD, a nationally renowned psychologist specializing in the relationship of mood and psychopathology, and the clinical assessment of children and families.

Heavy Periods: Causes, Symptoms and Treatment
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Heavy Periods: Causes, Symptoms and Treatment

Heavy menstrual bleeding is a common problem during adolescence. Heavy menstrual bleeding can negatively impact quality of life, school attendance, and participation in after-school sports and activities.

Research Staff Careers
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Research Staff Careers

The research we do here at Nationwide Children's impacts how we care for patients from Ohio and from around the world.

Nationwide Children's Hospital Names First Chief Data Sciences Officer
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Nationwide Children's Hospital Names First Chief Data Sciences Officer

Peter White, PhD, has been named the inaugural Chief Data Sciences Officer (CDSO) of the Abigail Wexner Research Institute (AWRI) at Nationwide Children's Hospital. The CDSO will lead biomedical data science initiatives to support Nationwide Children's mission as a leader in pediatric health care innovation.

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Nationwide Children’s Hospital to Host the On Our Sleeves 5K Presented by The Big Lots Foundation May 6 at the Columbus Zoo and Aquarium

The On Our Sleeves 5K presented by The Big Lots Foundation, scheduled for Saturday, May 6 at the Columbus Zoo and Aquarium, is a community run and walk to grow awareness, break stigmas, and raise funds for The On Our Sleeves® Movement For Children’s Mental Health. The On Our Sleeves Movement For Children’s Mental Health, created by Nationwide Children’s Hospital, works to provide expert-created resources to all U.S. communities so everyone can understand and promote mental health for children.

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