Center for Childhood Cancer Research
The mission of the Center for Childhood Cancer Research is to expand the understanding of the pathogenesis of childhood cancer and to improve strategies for diagnosis and treatment.
Our areas of focus include:
- Biology and therapy of rhabdomyosarcoma and other childhood tumors
- Chemotherapy of childhood solid tumors
- Regulation of alternative pre-mRNA splicing
- Regulation and function of tumor suppressor genes
- Oncolytic viral therapy in pediatric brain tumors
- Immunotherapy and cellular therapies that harness the natural ability of the immune system to fight cancers
The Abigail Wexner Research Institute is ranked among the top 10 for NIH funding among free-standing children's hospitals.
Affiliations and Collaborations
Inside our Zebrafish Facility: Genetic, Life-Saving Research
The Abigail Wexner Research Institute at Nationwide Children’s Hospital is home to our cutting-edge Zebrafish Facility. These tiny fish are used in multiple disciplines in thousands of laboratories around the world. Because Zebrafish are similar to humans, our researchers are able to use the system to study processes that are difficult or impossible to follow in other animals. The level of expertise and the state-of-the-art facility set us apart in this field. This research will bring hope to families and will help better treat children with life-threatening conditions and diseases. Come inside our facility and learn more about this genetic, life-saving research.
For Trainees
Faculty Positions
Step inside the Center for Childhood Cancer Research, and you’ll find clinicians and researchers collaborating under the same roof to understand pediatric cancer, how it develops and how to treat it — all while mentoring and educating the next generation of scientists. This is a team that understands collaboration is key to ambitious basic science and impactful translational research. Thanks to that approach, its researchers are responsible for some of the most groundbreaking discoveries in pediatric cancer today.
For Patients & Families
World-renowned Biopathology Center
The Biopathology Center at Nationwide Children’s Hospital serves as the only pediatric repository for pediatric solid tumor and is one of only two repositories for leukemia samples in the United States, Canada and Australia.