700 Children's® – A Blog by Pediatric Experts

Posted by: Natalie I. Rine, PharmD, BCPS, BCCCP on Jun 26, 2026


The Benadryl Challenge has been on social media since 2020 but has recently become popular again. The challenge involves taking multiple, large doses of diphenhydramine (also known as Benadryl) to induce hallucinations.

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About this Blog

Pediatric News You Can Use From America’s Largest Pediatric Hospital and Research Center

700 Children’s® features the most current pediatric health care information and research from our pediatric experts – physicians and specialists who have seen it all. Many of them are parents and bring a special understanding to what our patients and families experience. If you have a child – or care for a child – 700 Children’s was created especially for you.

Latest Posts

Toddler receiving eye drops.

The Parent's Guide to Pink Eye

Sep 10, 2015

Your child wakes up with something new and unexpected: their eyes are matted shut and they have trouble opening them. The right answer depends on the underlying problem. Read More

Person running up stairs on a hill.

Shin Splints

Sep 08, 2015

Shin splints are a common exercise problem and sports injury, but what exactly does it mean? The medical term for shin splints is medial tibia stress syndrome (MTSS). The stress occurs with the inflammation of muscles, connective tissue and bone tissue along the inner shin bone (tibia). Read More

Woman changing a baby's diaper.

How to Combat Diaper Rash

Sep 03, 2015

When babies are born their skin is soft, smooth and perfect. Then it happens- diaper rash. As a parent, you may be asking yourself “What did I do wrong?” The simple answer is – nothing. Diaper rash is a normal part of infancy. Read More

Three children standing with their parents for a photo.

Understanding Genetic Predisposition to Cancer

Aug 28, 2015

When a child is diagnosed with cancer, parents commonly ask, “Does this put my other kids at higher risk for developing cancer as well?” Most of the time, the answer to this question is “no”. Read More

Young child blowing her nose into tissue.

Oral Allergy Syndrome: The Hidden Allergy

Jul 30, 2015

Do you also have seasonal allergies to tree, grass, or ragweed pollen? If so, you likely have oral allergy syndrome (OAS), also known as pollen-food syndrome. Read More

The Dangers of Pinterest

Jun 30, 2015

I’ll admit I’m no Martha Stewart. But something about Pinterest sucks me in. But as a childhood injury researcher, I have a problem with Pinterest. I see ideas for children that are completely unsafe for them. Read More

Brown bottles on table with flowers.

A Doctor's Take on Essential Oils

Jun 04, 2015

Essential oils are all the rage. You’ve probably also wondered if they really work. Are they safe? And is buying into the movement a waste of money or an effective use of a natural remedy? Read More

Two boys wrestling

Preventing Skin Infections in Wrestling

Jun 02, 2015

Wrestlers use strength, agility and finesse to wrestle for victory against their opponent. In every practice and match, skin-to-skin contact between two players is inevitable. This environment of skin and sweat is a breeding pool for organisms such as bacteria, fungus, and viruses. Read More