Advancing Clinical Care of Kidney and Related Disorders Through Research


The Nephrology Clinic at Nationwide Children’s gives comprehensive treatment to children and adolescents with kidney and urinary tract problems. Among the conditions addressed are kidney failure, developmental abnormalities of the kidneys, urinary tract infections, kidney stones, nephrotic syndrome, high blood pressure, metabolic bone disease and inflammatory diseases of the kidneys such as glomerulonephritis.

US News Badge Nephrology

The Section of Nephrology at Nationwide Children's is ranked by U.S. News & World Report.

Our Mission Statement

As the leader in pediatric care, the Nephrology Division at Nationwide Children’s provides comprehensive acute and chronic nephrology services, urinary tract evaluation, dialysis, kidney transplantation, hypertension diagnostics and management, as well as treatment of metabolic bone disease. Pediatric patients with all forms of kidney and urinary tract diseases will have access to world-class diagnostic, treatment, education, and research services. The Nephrology Division is staffed by pediatric experts who provide patients and their families unparalleled and innovative care.

Meet Our Leadership

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John David Spencer

John David Spencer, MD, is chief of the Division of Nephrology, Principal Investigator in the Center for Clinical and Translational Research in the Abigail Wexner Research Institute at Nationwide Children's Hospital and an Assistant Professor of Pediatrics at the Ohio State University College of Medicine.

Hiren Patel

Hiren P. Patel

Hiren Patel, MD, is chief of the Section of Nephrology and medical director of the Kidney Transplant Program at Nationwide Children's Hospital. His clinical interests include glomerular and tubular disorders, acute kidney injury, chronic kidney disease and end-stage renal disease. His research interests include improving clinical outcomes in chronic kidney disease, particularly in the dialysis and renal transplant populations.

Nephrology Outreach and Support Services

Outreach and support services include:

  • Renal Basic Science Research Laboratory
  • Renal development
  • Clinical research
  • Hypertension
  • Pediatric renal transplantation
  • Kidney stones
  • Urinary tract infection
  • Pediatric renal dietician, clinical nutrition support
  • Dedicated renal social worker and psychologist
  • Homecare


Patient receiving dialysis treatment


Nationwide Children’s has a pediatric-specific dialysis unit on-site to provide acute and chronic dialysis therapy for children with severe kidney failure.

Young girl in hospital bed

Kidney Transplant Program

Our program serves children and adolescents in need of a kidney transplant due to birth anomalies, disease processes and acute/chronic kidney injury.

Metabolic Bone Clinic patient

Metabolic Bone Clinic

We provide comprehensive evaluation, diagnosis and management of various skeletal disorders, including Osteogenesis Imperfecta (OI) and Osteopenia/Osteoporosis.

Nationwide Children's Hospital Patient Stock Photo

Urology and Nephrology Combined Clinic

For patients who need care from experts in both urology and nephrology, our combined clinic offers many advantages. Our combined clinic serves patients with many types of conditions related to the urinary system and kidneys.

Meet Our Patients


Alex's Story

Read Alex's Story

Name: Alex G.
Condition(s): Nephrotic Syndrome
Age Today: 10 Years

For two years of Alex's life, everything seemed fine. The his mother noticed that he wasn’t feeling well, battling persistent stomach problems and puffy eyes. At first she thought they were dealing with allergies, but as Alex worsened, tests revealed he had a rare kidney disorder called nephrotic syndrome.

Brielle's story

Read Brielle's Story

Name: Brielle
Condition(s): Kidney Transplant, Wilms Tumor

When Brielle was 11 months old, she was diagnosed with Wilms' tumor in both kidneys. The kidneys were removed four months later, and she began dialysis four times a week. After being cancer-free for two years, Brielle became a candidate for kidney transplant.

Kaylor's Story

Read Kaylor's Story

Name: Kaylor B.
Condition(s): Nephrotic Syndrome
Age Today: 9 Years

About a month before Kaylor's 5th birthday, he developed an upper respiratory infection. During a visit to the doctor, I noticed when they took his weight it had spiked up 10 pounds, but I couldn't remember the last time I weighed him.

Nephrology Research 

In addition to providing outstanding clinical care, members of the Section of Nephrology conduct research to improve patient outcomes.

Urine Analysis Device

Research and Innovation

In addition to providing outstanding clinical care, members of the Section of Nephrology conduct research to improve patient outcomes.

Nationwide Children's Hospital Exterior

Nephrology Team Grants

The Section of Nephrology is dedicated to advancing clinical care of kidney and related disorders through research. See a list of current research grants awarded to our team.

The Nephrology and Urology Research Affinity Group

Members of the Section of Nephrology also participate in the Nephrology and Urology Research Affinity Group (NURAG). NURAG is composed of medical faculty, residents and fellows from the Nephrology and Urology programs at Nationwide Children’s Hospital. NURAG also includes members of The Research Institute at Nationwide Children’s whose research projects focus on the fields of nephrology, urology and associated disciplines.


The Midwest Pediatric Nephrology Consortium (MWPNC)

The Midwest Pediatric Nephrology Consorium (MWPNC) was formed in 2004 to develop and execute multi-center clinical and translational studies related to pediatric kidney diseases. The MWPNC is comprised of 30 pediatric nephrology programs primarily from the Midwest and Ontario that meets every six months to accomplish its work. The MWPNC has published 11 peer-reviewed manuscripts and conducted 11 funded research projects. Through these efforts, the MWPNC is re-making the way that pediatric nephrologists improve patient care through clinical research. John D. Mahan, MD, and William E. Smoyer, MD, are two of the founders and serve on the MWPNC Steering Committee.

Conditions We Treat

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