Research and Innovation

William Smoyer

Largest Study of Glomerular Diseases Sheds Light on Pediatric Subtypes

Researchers find differences in clinical presentation and treatment patterns between subtypes and between adult and pediatric diagnoses.

Doctor with child holding teddy bear

Nephritis Identified as High Research Priority Area For Childhood-Onset Lupus

In an effort to establish research priorities in childhood-onset systemic erythematous lupus (cSLE), researchers at Nationwide Children’s Hospital partnered with the Lupus Foundation of America (LFA) and Childhood Arthritis and Rheumatology Research Alliance (CARRA).

Antimicrobial peptides

In Defense Against Peritonitis, Antimicrobial Peptides May Help on Multiple Fronts

Study suggests AMPs have potential as biomarkers for peritonitis, risk stratification and treatment.

Pediatrics Nationwide

RNase 7: Paving the Way for a Natural, Antibiotic-Free Treatment for Urinary Tract Infections

The latest in the body of antimicrobial peptide research suggests RNase7 may be a useful prognostic marker and potential therapeutic option for UTIs.

Brian Becknell, MD, PhD

Uroplakin Plaque Key to Protecting Kidney During Urinary Tract Obstruction

Plaque appears to help remodel urothelium, allowing kidney to hold excess urine without damage.

M. Brian Becknell, MD, PhD

End-stage Renal Disease in Children with Obstructive Uropathy Is Predicted by Common Clinical Markers

Frequently measured clinical markers can predict end-stage renal disease in children with obstructive uropathy, according to a new study published in Pediatric Nephrology.

John David Spencer, MD

John David Spencer, MD, Named Nephrology Division Chief at Nationwide Children’s Hospital

An accomplished physician-scientist, Dr. Spencer’s research primarily focuses on basic and translational science related to antimicrobial peptide biology in the urinary tract.