Research and Innovation

M. Brian Becknell, MD, PhD

End-stage Renal Disease in Children with Obstructive Uropathy Is Predicted by Common Clinical Markers

The findings could ultimately help stratify patients based on their risk for experiencing renal failure.

Antimicrobial peptides

In Defense Against Peritonitis, Antimicrobial Peptides May Help on Multiple Fronts

Study suggests AMPs have potential as biomarkers for peritonitis, risk stratification and treatment.

William Smoyer

Largest Study of Glomerular Diseases Sheds Light on Pediatric Subtypes

Researchers find differences in clinical presentation and treatment patterns between subtypes and between adult and pediatric diagnoses.

Brian Becknell, MD, PhD

Uroplakin Plaque Key to Protecting Kidney During Urinary Tract Obstruction

Plaque appears to help remodel urothelium, allowing kidney to hold excess urine without damage.

John David Spencer, MD

John David Spencer, MD, Named Nephrology Division Chief at Nationwide Children’s Hospital

An accomplished physician-scientist, Dr. Spencer’s research primarily focuses on basic and translational science related to antimicrobial peptide biology in the urinary tract.

Daryl J. McLeod, MD, and John David Spencer, MD

Urology/Nephrology Combined Clinic Offers Benefits for Patients, Physicians and Researchers

A highly specialized clinic provides efficient care for patients with rare or complicated urinary tract conditions and offers patients, clinicians and researchers a win-win-win scenario.

Urine Concentration App Outperforms Common Clinical Hydration Measures

An innovative mobile phone application determined hydration status better than thirst, urine color scales and dipstick tests in a pilot study.