Research and Innovation

William Smoyer

Largest Study of Glomerular Diseases Sheds Light on Pediatric Subtypes

Researchers find differences in clinical presentation and treatment patterns between subtypes and between adult and pediatric diagnoses.

Brian Becknell, MD, PhD

Uroplakin Plaque Key to Protecting Kidney During Urinary Tract Obstruction

Plaque appears to help remodel urothelium, allowing kidney to hold excess urine without damage.

M. Brian Becknell, MD, PhD

End-stage Renal Disease in Children with Obstructive Uropathy Is Predicted by Common Clinical Markers

Frequently measured clinical markers can predict end-stage renal disease in children with obstructive uropathy, according to a new study published in Pediatric Nephrology.

John David Spencer, MD

Insulin Resistance Appears to Disrupt Natural Defense Against Urinary Tract Infections

Insulin receptor signaling provides a possible target to boost protection for patients with diabetes and prediabetes.

Daryl J. McLeod, MD, and John David Spencer, MD

Urology/Nephrology Combined Clinic Offers Benefits for Patients, Physicians and Researchers

A highly specialized clinic provides efficient care for patients with rare or complicated urinary tract conditions and offers patients, clinicians and researchers a win-win-win scenario.

Could Antimicrobial Peptides Be Biomarkers for Obstructive Uropathy?

New research reveals the expression of antimicrobial peptides — long associated only with infections — in children with obstructive uropathy, creating potential for a wide range of clinical applications.