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Study Finds Youth with Concussion May Benefit from Monitoring Sleep and Limiting Daytime Naps

Researchers at Nationwide Children’s Hospital have found that when it comes to concussion recovery, sleep matters. In a study published today in British Journal of Sports Medicine, researchers found that limiting daytime sleep and getting approximately seven hours of sleep each night in the first week after a concussion may speed up recovery.

Dr. Gary Smith Named Allen Distinguished Scholar in Pediatric Research
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Dr. Gary Smith Named Allen Distinguished Scholar in Pediatric Research

Gary A. Smith, MD, DrPH, director and founder of the Center for Injury Research and Policy (CIRP) in the Abigail Wexner Research Institute at Nationwide Children’s Hospital, has been named the 2026 Steve Allen MD Distinguished Scholar in Pediatric Research. The award is given in honor of former Nationwide Children’s CEO, Steve Allen, MD, and his role in developing Nationwide Children’s into a preeminent pediatric research institution.

Nationwide Children’s Hospital Researcher Lauren Bakaletz, PhD, Honored by AAAS as Lifetime AAAS Fellow
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Nationwide Children’s Hospital Researcher Lauren Bakaletz, PhD, Honored by AAAS as Lifetime AAAS Fellow

The American Association for the Advancement of Science (AAAS), the world’s largest general scientific society and publisher of the Science family of journals, has elected Lauren Bakaletz, PhD, director of the Center for Microbial Pathogenesis in the Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital to the newest class of AAAS Fellows, among the most distinct honors within the scientific community.

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Nationwide Children’s Hospital Launches “Empower the Possible” Campaign with Historic 10-Year, $100 Million Commitment from Nationwide Foundation

Nationwide Children’s Hospital is honored to announce that it has received a historic 10-year commitment of $100 million from the Nationwide Foundation. This landmark announcement marks the public launch of the hospital’s “Empower the Possible” campaign that with other gifts brings the campaign’s fundraising total to more than $270 million, more than halfway to the campaign goal of $500 million.

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Featured Physician

Sean Tabaie, MD, MBA, FAAOS, FAOA, is a pediatric orthopedic surgeon at Nationwide Children’s Hospital and clinical professor at The Ohio State University College of Medicine. At Nationwide Children’s, Dr. Tabaie serves as the director of the Cerebral Palsy & Neuro-Orthopedics Program, medical director of the Honda Center for Gait Analysis and Mobility Enhancement, director of the Neuro-Orthopedics Fellowship, associate director of the Pediatric Orthopedics Fellowship and associate director of the Orthopedic Innovation Program.

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Human MicroRNA Inhibits Expression of Pathogenic Gene Underlying Facioscapulohumeral Muscular Dystrophy

Facioscapulohumeral muscular dystrophy (FSHD) is caused by aberrant expression of the DUX4 gene in skeletal muscles. Researchers at Nationwide Children’s Hospital have recently demonstrated that an endogenous human microRNA, miR-675, inhibits DUX4 expression and protects muscles from DUX4-mediated cell death in a mouse model when administered via gene therapy. They also showed that the small molecule-based treatments that upregulate miR-675 inhibited DUX4 mRNA and DUX4-associated biomarkers in myotubes derived from patients with FSHD.

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New Insights into the Role of the NOTCH1 Gene in Congenital Heart Defects

A new study published in Circulation Research provides novel insights into how mutations in the NOTCH1 gene may lead to abnormal differentiation and proliferation of cardiomyocytes and contribute to ventricular hypoplasia and other structural anomalies found in congenital heart defects in humans.

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FDA Grants Nationwide Children’s Hospital Researchers Safe-To-Proceed Authorization on First-In-World CAR-NK Cells Made with CRISPR/AAV

Researchers at Nationwide Children’s Hospital have received safe-to-proceed approval from the Food and Drug Administration (FDA) for Universal-Donor CD38KO CD33CAR-NK cells, to be studied in a forthcoming clinical trial. The Phase 1 trial will study the safety of the novel therapy in patients with advanced, high-risk acute myeloid leukemia (AML).

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Study Finds Teens Driving Older Vehicles Have Increased Risk for Fatal Crashes

Motor vehicle crashes are the leading cause of death for U.S. teens. Newer vehicles and driver assistance technologies show promise in reducing crashes and injury severities. Researchers at Nationwide Children’s Hospital reviewed national fatal crash data (2016-2021) and examined the vehicle age and driver assistance technologies of vehicles driven by teen and middle-aged drivers, and their associations with driver deaths during fatal crashes.

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