700 Children's® – A Blog by Pediatric Experts

Posts by Natalie I. Rine, PharmD, BCPS, BCCCP

Posted by: Natalie I. Rine, PharmD, BCPS, BCCCP on Jun 26, 2026


The Benadryl Challenge has been on social media since 2020 but has recently become popular again. The challenge involves taking multiple, large doses of diphenhydramine (also known as Benadryl) to induce hallucinations.

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About this Blog

Pediatric News You Can Use From America’s Largest Pediatric Hospital and Research Center

700 Children’s® features the most current pediatric health care information and research from our pediatric experts – physicians and specialists who have seen it all. Many of them are parents and bring a special understanding to what our patients and families experience. If you have a child – or care for a child – 700 Children’s was created especially for you.

Latest Posts

photo of gummy bears

Keeping Kids Safe Around Cannabis (Marijuana) Edibles

Jul 15, 2025

As a pediatrician in training, I have seen too many children come into the Emergency Department or admitted to the hospital with abnormal behavior or difficulty breathing from eating marijuana edibles. I urge all parents and caregivers to follow a few simple steps to keep children safer. Read More

A hand holds an electronic cigarette emitting visible vapor against a dark background.

E Cigarette Dangers and Vaping Illness

Jul 08, 2025

E-cigarettes may seem safer than traditional smoking, but they pose serious risks, especially for children and teens. From nicotine addiction and poisoning to life-threatening lung illness, learn why vaping is dangerous and how to protect your family. Read More

rainbow fentanyl color

Rainbow Fentanyl: A Dangerous Trend

Sep 10, 2024

Although these substances may resemble candy, don’t be fooled—they are deadly. It is important for parents to be aware of this new fentanyl disguise and to keep it away from children. Read More

mushrooms growing out of the ground

Watch Out for Dangerous Mushrooms

Sep 04, 2024

In Ohio, we have a broad variety of types of mushrooms, including some of the deadliest types including “the death angel” or amanita phalloides. Mushrooms grow quite rapidly and may appear to spring up suddenly overnight. Read More

The Dangers of Caffeine Powder

Aug 30, 2024

AHH caffeine! That first cup of coffee in the morning (or for some a diet coke)! Sixty percent of American coffee drinkers say they need coffee to start their day, and caffeine-enhanced products like energy drinks have become increasingly popular in teens and young adults. Read More

Pet Medicine and Poison Prevention: Keeping Kids Safe

Aug 30, 2024

For many people, pets are an important part of the family and owning a pet can have many benefits. However, if you also have children, having a pet can come with some unexpected risks. Read More

hand holding a glass under sink filling up the glass with water

Nitrate Levels in the Water Are High, Should You Be Concerned?

Aug 30, 2024

I just heard that Nitrate levels in the water are high, should I be concerned? Well, for most of us the answer is no. The concern is mainly for two special groups. Read More

Make up brush and make up powder.

Asbestos in Children's Makeup: What's the Risk to Your Child?

Aug 29, 2024

Asbestos can be a scary thing. And, in a child’s toy or makeup it can seem especially worrisome. For parents of children who recently heard about a recall of children’s makeup, here’s some information that may be helpful. Read More