Nationwide Children's Research News
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Aug 08, 2023
From Bench to Bedside: Patient with Duchenne Muscular Dystrophy Receives First Dose of Gene Therapy Developed at Nationwide Children’s Hospital
In a landmark moment for the Abigail Wexner Research Institute at Nationwide Children’s, a 5-year-old from Bellefontaine, Ohio, received the first dose of a recently approved gene therapy for Duchenne muscular dystrophy at Nationwide Children’s Hospital, where the therapy was invented and initially tested.
Jun 22, 2023
FDA Approves First Gene Therapy Treatment for Duchenne Muscular Dystrophy Developed at the Abigail Wexner Research Institute at Nationwide Children’s Hospital
Today, the Abigail Wexner Research Institute at Nationwide Children’s Hospital praised the Food and Drug Administration (FDA) for its accelerated approval of SRP-9001/ELEVIDYS for Duchenne muscular dystrophy (DMD) following decades of research in its Center for Gene Therapy to help patients with neuromuscular diseases.
Jun 13, 2023
Mapping the 3D Structure of Rhabdomyosarcoma Chromatin
In a paper published in Nucleic Acids Research Cancer (NAR Cancer), researchers from the Center for Childhood Cancer Research at Nationwide Children’s and their collaborators report a comprehensive 3D chromatin structural analysis and characterization of rhabdomyosarcoma (RMS).

Apr 25, 2023
Nationwide Children's Hospital Names First Chief Data Sciences Officer
Peter White, PhD, has been named the inaugural Chief Data Sciences Officer (CDSO) of the Abigail Wexner Research Institute (AWRI) at Nationwide Children's Hospital. The CDSO will lead biomedical data science initiatives to support Nationwide Children's mission as a leader in pediatric health care innovation.

Apr 06, 2023
Using Machine Learning in the Electronic Medical Record to Save Lives
In a report published in Pediatric Critical Care Medicine, a team from Nationwide Children's Hospital describes a machine learning tool for timely identification of hospitalized children at risk for deterioration – a worsening clinical condition with increased risk of morbidity and mortality. The tool, which is trained on disease-specific groups, promisingly outperformed the existing situational awareness program in identifying at-risk children.
Feb 27, 2023
Dr. Patrick Gallagher of Yale University Named Director of Perinatal Research Center at Nationwide Children's Hospital
Patrick Gallagher, MD, from Yale University has been named the new director of the Center for Perinatal Research in the Abigail Wexner Research Institute at Nationwide Children's Hospital.
Jan 20, 2023
New Insights into the Role of the NOTCH1 Gene in Congenital Heart Defects
A new study published in Circulation Research provides novel insights into how mutations in the NOTCH1 gene may lead to abnormal differentiation and proliferation of cardiomyocytes and contribute to ventricular hypoplasia and other structural anomalies found in congenital heart defects in humans.
Jan 19, 2023
Cynthia Gerhardt, PhD, Named Chief Clinical Research Officer at Nationwide Children's Hospital
Cynthia A. Gerhardt, PhD, director, Center for Biobehavioral Health in the Abigail Wexner Research Institute at Nationwide Children's Hospital, has been appointed Chief Clinical Research Officer (CCRO) at Nationwide Children's.

Jan 18, 2023
Genomic Medicine, Physician Dedication Give Family Answers About Teen’s Rare Disease
Through whole exome sequencing performed in 2020 at the Steve and Cindy Rasmussen Institute for Genomic Medicine at Nationwide Children’s, one family was finally able to put a real name to their adolescent's rare disease.

Nov 03, 2022
“The Ripple Effect” New Study Illustrates Vast Influence Children’s Mental Health Concerns have on Workforce Challenges in America
“The Ripple Effect” study from On Our Sleeves found that the mental health of their children remains a concern for the large majority of working parents, with almost half of all parents reporting that in the past year their child's mental health has been somewhat or extremely disruptive to their ability to work on most days.