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Article
Wedemeyer Lab Staff
Learn more about principal investigator Michelle Wedemeyer, MD, PhD, and her dynamic team in the Wedemeyer Lab.
Specialty
Inflammatory Bowel Disease Center
Our nationally recognized center uses a specialized, multidisciplinary approach to provide expert, comprehensive care for children with Crohn’s disease and ulcerative colitis. We provide intensive support through clinical management, patient and family education, dietary guidance and counseling.
Article
Drug-Related Poisoning
The cause of these poisonings has shifted over the past decade. Prescription drug-related poisonings now lead to more deaths and emergency department visits than illegal drugs.
News
Study supports virotherapy as a potential treatment for brain tumors
A new study provides additional evidence of the efficacy of virotherapy for glioblastoma, the most deadly type of brain tumor. The research findings, published Feb. 1, 2022, in Clinical Cancer Research, indicate that an oncolytic herpes simplex virus, G207, appears to boost immune response and that this is associated with better overall survival for patients with glioblastoma.
Article
Biologics Manufacturing
Biologics Manufacturing maintains facilities, equipment and personnel for manufacturing a wide range of cellular therapeutic products for clinical trials including natural killer (NK) cells, CAR NK and CAR T cells and a tissue engineered vascular graft.
Genomics Research and Personalized Medicine
Over the next five years, new investments, partnerships and infrastructure will allow The Steve and Cindy Rasmussen Institute for Genomic Medicine to develop novel genomics-enabled research, advance genomics-driven precision medicine and pursue further breakthroughs in the technology of computational genomics and informatics.
Condition
Medulloblastoma
Medulloblastomas are tumors that develop in the brain, most commonly in a region called the cerebellum. The cerebellum is located next to the brainstem and controls coordination, balance and other motor skills.
News
Nationwide Childrens Hospital Neuromuscular Disorder Podcasts Now Available on iTunes
In 2010, the Center for Gene Therapy at Nationwide Children’s Hospital launched a monthly podcast entitled, “This Month in Muscular Dystrophy,” featuring internationally known scientists discussing the latest research in muscular dystrophy and other neuromuscular disorders.
Article
Chen Lab
The Chen Lab examines pathways involved in vascular remodeling and smooth muscle cell proliferation, the pathogenic hallmarks of PH. Its research is focused on the phosphodiesterase 3 (PDE3) pathway and the distinct function and activity of each isoform (PDE3A and PDE3B) and their mechanistic interaction with the nitric oxide (NO)-cGMP pathway, which remain largely unknown.
News
New Study Finds Zipline-Related Injuries Are Rapidly Increasing
The popularity of ziplining has skyrocketed rapidly in recent years. The number of commercial ziplines in the U.S. rose from 10 in 2001 to more than 200 in 2012, in addition to more than 13,000 amateur ziplines which can be found in outdoor education programs, camps, and backyards.