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Immune Profiling Leads to Implications for Immunotherapy for NF1-Associated Tumors

Neurofibromatosis type 1 (NF1) — an autosomal dominant disorder affecting approximately one in every 3,500 people — results in dysfunctional neurofibromin, a protein expressed throughout the body and involved in the RAS signaling pathway.

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Researchers Develop Effective Strategy for Disrupting Bacterial Biofilms, Cause of Many Chronic and Recurrent Diseases

Biofilms are communities of bacteria that adhere to a surface and are nearly impossible to eradicate when they are pathogenic, or disease-causing. Fortunately, a discovery from the laboratories of Lauren Bakaletz, PhD, and Steven Goodman, PhD, in The Research Institute at Nationwide

5 Questions Parents Need to Ask Before Leaving the Emergency Room
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5 Questions Parents Need to Ask Before Leaving the Emergency Room

A sick child is every parent’s concern. Most aim to alleviate their kid’s discomfort at home and follow up with their pediatrician, but when an emergency room visit is required, that concern can become overwhelming.

Why Taking Care of Your Physical Health and Mental Health Are Equally Important
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Why Taking Care of Your Physical Health and Mental Health Are Equally Important

The reality is that mental health and physical health are deeply connected and the attention and treatment we give to one area will naturally influence our health in the other.

Duchenne Muscular Dystrophy: Improving Patient Care Through Teamwork
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Duchenne Muscular Dystrophy: Improving Patient Care Through Teamwork

Duchenne Muscular Dystrophy (DMD) is a genetic disease that causes muscle weakness, eventual loss of the ability to walk, and failure of the heart and lung. Boys with DMD typically do not survive past their twenties, but standardization of care and cutting edge research is changing this outlook.

Kidney Transplants and Donation: Having a Tough Conversation that Could Save a Life
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Kidney Transplants and Donation: Having a Tough Conversation that Could Save a Life

Most parents feel overwhelmed and nervous to bring up transplant around others. It is important for caregivers to know that others want to help, but they cannot help if you do not let them know how.

How to Choose an Urgent Care
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How to Choose an Urgent Care

Middle-of-the-night earache? Weekend sports injury? Not every illness or accident needs the ER—but not every urgent care is right for kids, either. Learn how to tell what’s an emergency, what can wait, and how to choose an urgent care center with true pediatric expertise, including options from Nationwide Children’s in Central Ohio.

 Ketogenic Diet: An Ancient Treatment in Modern Times
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Ketogenic Diet: An Ancient Treatment in Modern Times

For some kids with epilepsy, seizure medications don’t provide full control—so doctors may turn to specialized medical diets like the ketogenic diet. Learn how this high-fat, low-carbohydrate approach works, which foods are included and avoided, possible side effects, and why it should only be started under the guidance of an expert epilepsy care team.

Transitional Care in Gynecology: When Should Your Child Switch to an Adult Provider?
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Transitional Care in Gynecology: When Should Your Child Switch to an Adult Provider?

A woman’s first visit to an adult GYN practice is a great opportunity for her to take further ownership of her gynecologic health as she transitions to another stage in her life. An adult GYN provider treats women’s breast and pelvic health issues and associated surgical needs, hormonal issues, pregnancy and postnatal care.

Delirium
Condition

Delirium

Delirium is a serious disturbance in mental abilities. It involves changes in behavior, confused thinking, and reduced awareness of a person's surroundings. Delirium is a serious complication of medical illness.

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