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Two Faculty in The Research Institute at Nationwide Childrens Hospital Named AAAS Fellows
Brian K. Kaspar, PhD, and Veronica J. Vieland, PhD, principal investigators in The Research Institute at Nationwide Children’s Hospital, have been named Fellows of the American Association for the Advancement of Science (AAAS).
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Nationwide Children’s Hospital Researchers Review Influences of Maternal Diabetes on Fetal Heart Development
In a comprehensive review recently published in Birth Defects Research, Vidu Garg, MD, and Madhumita Basu, PhD, offer a “state of the science” look at the impact of maternal diabetes, and potential gene-environmental influences in that context, on fetal heart development.
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Investigators Develop Technique to Effectively Edit NK Cells to Target Specific Cancer Cells
Originally, NK cells seemed promising for a natural therapy to fight cancer due to their innate ability to recognize any cells expressing stress or signs of infection. But investigators quickly realized they faced three key challenges: first, it was difficult to grow a large enough number of NK cells in the lab to offer useful infusions at a reasonable cost; second, an ideal universal donor solution was needed to make NK cell products faster, more reliably and with off-the-shelf availability; and third, NK cells were resistant to genetic modifications that might help them better target specific types of cancer cells. Nationwide Children’s Hospital investigators and their collaborators painstakingly solved the first two problems over the past decade. Now, they’ve conquered the third.
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Oligodendrocytes Induce Motor Neuron Death in ALS
A first-of-its-kind oligodendrocyte in vitro model shows that human cells normally supportive of motor neuron function play an active role in amyotrophic lateral sclerosis pathogenesis – and this discovery may point the way toward therapeutic timing and targets.
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International Symposium Explores Hybrid Approach to Congenital Heart Disease
Interventional cardiologists and cardiothoracic surgeons throughout the United States, North and South America, Europe, Asia and Australia, who treat patients with congenital heart disease, will gather at Nationwide Childrens Hospital June 16-18, 2008 for the third International Symposium on the
Article
Fecal Fat Quantitative Test (72 Hour Collection)
How to prepare for a fecal fat quantitative test.
Article
Sickle Cell Disease and Fever
Children with sickle cell disease (SCD) are more likely to get infections, especially bacterial infections. The spleen helps to fight infections. In patients with sickle cell disease, the spleen does not work as well. Fever may be the first and only sign of infection.
Article
Microarray Analysis Test
The microarray analysis test is used to find out if your child has a medical condition caused by a missing or extra piece of chromosome material. This test is also known by several other names, such as chromosomal microarray, whole genome microarray, array comparative genomic hybridization or SNP microarray.
Article
Urologic Concerns
After the pull-through procedure and colostomy closure, many parents feel that the stress is now behind them. But they must realize that the new focus should then move to the treatment of constipation and urologic management.