Nationwide Children's News Releases
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Mar 19, 2012
Newborn Screening for Duchenne Muscular Dystrophy Shows Promise as an International Model
Investigators at Nationwide Children’s Hospital, working with the DNA Sequencing Core Facility at the University of Utah, have developed an approach to newborn screening (NBS) for the life-threatening genetic disorder, Duchenne muscular dystrophy (DMD) and potentially other muscular
Feb 29, 2012
Nationwide Childrens Hospital Neuromuscular Disorder Podcasts Now Available on iTunes
In 2010, the Center for Gene Therapy at Nationwide Children’s Hospital launched a monthly podcast entitled, “This Month in Muscular Dystrophy,” featuring internationally known scientists discussing the latest research in muscular dystrophy and other neuromuscular disorders.
Feb 22, 2012
Study: Muscle Regeneration May Provide Ideal Environment for Rhabdomyosarcoma
Inflammation, cell division and cell differentiation that occur during skeletal muscle regeneration may provide an ideal environment for the highly malignant tumor, rhabdomyosarcoma to arise.
Feb 15, 2012
Grant Provides Funding Toward Gene Therapy Clinical Trial to Replace the DMD Gene in All of the Leg Muscles of Duchenne Patients
Investigators in the Center for Gene Therapy in The Research Institute at Nationwide Children’s Hospital are working toward an approach to replace the defective gene in Duchene muscular dystrophy (DMD) by treating all of the muscles in the leg, thanks to funding from Jesse’s Journey.
Nov 02, 2011
Nationwide Children's Hospital and Ohio State Researchers Design a Viral Vector to Treat a Genetic Form of Blindness
Researchers at Ohio State University Medical Center and Nationwide Children’s Hospital have developed a viral vector designed to deliver a gene into the eyes of people born with an inherited, progressive form of blindness that affects mainly males.
Oct 03, 2011
Nationwide Childrens Hospital Researchers Receive Neurology Award for Contribution to Clinical Neuroscience
Jerry Mendell, MD, director of the Center for Gene Therapy in The Research Institute at Nationwide Children’s Hospital, and his fellow researchers, are the latest recipients of the Annals of Neurology prize for an outstanding contribution to clinical neuroscience. The study which helped Dr.
Aug 10, 2011
Human-Cell-Derived Model of ALS Provides a New Way to Study the Majority of Cases
For decades, scientists have studied a laboratory mouse model that develops signs of the paralyzing disease amyotrophic lateral sclerosis (ALS) as they age.
May 25, 2011
Nationwide Childrens Hospital Researchers Receive NIH Grant for the Move Toward Clinical Trials Targeting the Lysosomal Storage Disease MPSIIIB
Investigators at Nationwide Children’s have received a grant from the National Institutes of Health (NIH) to help move a therapy for MPS IIIB that has been shown effective in mice toward clinical trials in humans.
Jan 10, 2011
Patient-Derived Embryonic Stem Cells Help Deliver Good Genes in a Model of Inherited Blood Disorder
Researchers at Nationwide Children’s Hospital report a gene therapy strategy that improves the condition of a mouse model of an inherited blood disorder, Beta Thalassemia. The gene correction involves using unfertilized eggs from afflicted mice to produce a batch of embryonic stem cell lines.
Oct 06, 2010
Gene Therapy Reveals Unexpected Immunity to Dystrophin in Patients with Duchenne Muscular Dystrophy
An immune reaction to dystrophin, the muscle protein that is defective in patients with Duchenne muscular dystrophy, may pose a new challenge to strengthening muscles of patients with this disease, suggests a new study appearing in the October 7, 2010, issue of The New England Journal of Medicine.