Translational Research

Some current examples of IGM translational genomics programs include the following areas:

  • Cancer Diagnosis and Treatment

  • Computational Genomics

  • Genomics of Rare Disease

  • Genomics of Epilepsy and Seizure Disorders

  • Healthy Kids Genome Project

  • Congenital Heart Disease

  • Microbiome

  • Methylation

IGM Cancer Genomics Protocol

IGM has partnered with the Hematology/Oncology department at Nationwide Children’s to develop a genomics protocol for comprehensive clinical- and research-based testing for patients with pediatric cancers and/or hematologic disorders. Initially, this translational research and clinical focus will be on patients with relapsed or treatment refractory disease and/or rare tumor types. Research results may be confirmed under CAP/CLIA standards and utilized for patient management, informing diagnosis, evaluating eligibility for targeted therapeutics and clinical trials, and providing information on prognosis.

 clinical laboratory

The IGM Clinical Laboratory also tests cancer specimens for risk assignment and targeted therapy. We serve as a centralized clinical testing laboratory for the Children’s Oncology Group (COG), and offer the same assays for patients not enrolled on COG trials. Samples for COG trials are banked at Nationwide Children’s through the Biopathology Center.