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Investigators Develop Technique to Effectively Edit NK Cells to Target Specific Cancer Cells

Originally, NK cells seemed promising for a natural therapy to fight cancer due to their innate ability to recognize any cells expressing stress or signs of infection. But investigators quickly realized they faced three key challenges: first, it was difficult to grow a large enough number of NK cells in the lab to offer useful infusions at a reasonable cost; second, an ideal universal donor solution was needed to make NK cell products faster, more reliably and with off-the-shelf availability; and third, NK cells were resistant to genetic modifications that might help them better target specific types of cancer cells. Nationwide Children’s Hospital investigators and their collaborators painstakingly solved the first two problems over the past decade. Now, they’ve conquered the third.

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International Symposium Explores Hybrid Approach to Congenital Heart Disease

Interventional cardiologists and cardiothoracic surgeons throughout the United States, North and South America, Europe, Asia and Australia, who treat patients with congenital heart disease, will gather at Nationwide Childrens Hospital June 16-18, 2008 for the third International Symposium on the

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Two Faculty in The Research Institute at Nationwide Childrens Hospital Named AAAS Fellows

Brian K. Kaspar, PhD, and Veronica J. Vieland, PhD, principal investigators in The Research Institute at Nationwide Children’s Hospital, have been named Fellows of the American Association for the Advancement of Science (AAAS).

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Oligodendrocytes Induce Motor Neuron Death in ALS

A first-of-its-kind oligodendrocyte in vitro model shows that human cells normally supportive of motor neuron function play an active role in amyotrophic lateral sclerosis pathogenesis – and this discovery may point the way toward therapeutic timing and targets.

Blog

Urgent Care or Emergency Department for Childhood Injuries?

As the weather warms and kids head outdoors, the chance for injury rises. Where should families seek help when accidents occur? The answer depends on the nature of your child’s injury and the services offered in your community.

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Bacterial Vaginosis

Bacterial vaginosis is an infection of the vagina. Females of any age can have it and you do not have to be sexually active to get bacterial vaginosis.

Article

Graduate Students

First-year graduate students are able to do short rotations though the Abigail Wexner Research Institute laboratories prior to committing to their thesis laboratories.

4th Annual IMPAACT Summit: AAC Case Considerations for Beginning and Advanced AAC Clinicians

The 4th Annual IMPAACT Summit at Nationwide Children's Hospital is a two-day event with multiple visiting professionals and clinical therapy experts from Nationwide Children's. The focus of our summit this year is "Case Considerations for Beginning and Advanced AAC Clinicians."

14th Annual Bodies in Motion Conference

This course will educate participants in unique return to sport considerations for the adolescent athlete. Areas addressed in this course will include management of growth plate injuries, the role of imaging in rehabilitation, identifying and managing clinician burnout, ACL return to sport guidelines and testing, motion analysis for throwing and running athletes, and more!