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Sickle Cell Disease and Spleen Crisis

Sickle cells can block the blood vessels leading out of the spleen. When this happens, blood stays in the spleen instead of flowing through it. This causes the spleen to get bigger, and the blood counts to fall.

News

Massage Therapy Helps Manage Pain in Children with Sickle Cell Disease

Massage offers both physical and psychological benefits and is used at Nationwide Childrens Hospital in many areas including Rehabilitation, Physical Medicine and in patients who have received organ transplants, just to name a few.

Article

Sickle Cell Disease and Pain

Pain is a common problem for children with sickle cell disease (SCD). Sickled cells have a hard time moving through small blood vessels. They can pile up and clog the vessels, keeping oxygen from getting to certain parts of the body. This causes pain.

Article

Sickle Cell Disease and Stroke

Children with sickle cell disease (SCD) are at risk of having strokes. A stroke happens when the blood flow to or in the brain is blocked. This blockage slows down or stops oxygen to the brain. This can cause damage to the brain.

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Sickle Cell Treatment: What Does It Mean for Patients?

Something exciting happened in December 2023, when the U.S. Food and Drug Administration approved a gene therapy for the treatment of sickle cell disease in adult and pediatric patients 12 years and older who require regular red blood cell transfusions. Nationwide Children’s Hospital is one of a handful of facilities in the United States that is certified to have the advanced facilities and specially trained staff which are needed for the administration of the therapy.

Sickle Cell Disease (SCD) and Acute Chest Syndrome (ACS)

Sickle cell disease is an inherited blood disorder. Acute chest syndrome is a group of symptoms that occurs when sickled cells clump together in the lungs.

Article

Sickle Cell Disease and Fever

Children with sickle cell disease (SCD) are more likely to get infections, especially bacterial infections. The spleen helps to fight infections. In patients with sickle cell disease, the spleen does not work as well. Fever may be the first and only sign of infection.

News

Nationwide Children’s Hospital Delivers its First Infusion of CASGEVY™ for Patient with Sickle Cell Disease

Nationwide Children’s Hospital delivered its first commercial infusion of CASGEVY™ to 17-year-old Carlos A. from Dayton, Ohio. Today, Carlos is thriving at home, pain-free.

Article

SCOUTS Program

The Sickle Cell OUTreach in Schools (SCOUTS) Program supports children with sickle cell disease by providing the care and services they need – right at school.