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Nicolau Lab
Under the direction of Stefan Nicolau, MD, the Nicolau Lab aims to further the translational development of gene editing therapies for muscle disorders, with a particular emphasis on genetic mutations that require insertion of hundreds or thousands of base pairs into genomic DNA.
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Kendall Lab
Under the direction of Genevieve Kendall, PhD, the Kendall Lab focuses on developing basic and translational models of pediatric sarcomas—devastating and aggressive solid tumors with limited therapeutic options. The lab's goal is to apply the models as discovery- based tools to derive mechanistic insights for improving outcomes for children with cancer.
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Baker Lab Staff
Learn more about principal investigator Linda Baker, MD, and her dynamic team in the Baker Lab.
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Ruiz-Rosado Lab
Under the direction of Juan de Dios Ruiz-Rosado, PhD, the Ruiz-Rosado lab focuses on understanding the cellular immune mechanisms that contribute to the resistance or susceptibility to urinary tract infections, particularly acute pyelonephritis (APN), and the development of renal scarring following APN.
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Lab Staff
Learn more about principal investigator Albert Isaacs, MD, PhD, and his dynamic team in the Isaacs Lab.
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Wedemeyer Lab
The Wedemeyer Laboratory seeks to apply state of the art genomics technologies to better understand common neurosurgical disease processes in children and improve the overall neurosurgical care for the children in our community.
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Chen Lab
The Chen Lab examines pathways involved in vascular remodeling and smooth muscle cell proliferation, the pathogenic hallmarks of PH. Its research is focused on the phosphodiesterase 3 (PDE3) pathway and the distinct function and activity of each isoform (PDE3A and PDE3B) and their mechanistic interaction with the nitric oxide (NO)-cGMP pathway, which remain largely unknown.
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Spencer Lab Staff
Learn more about principal investigator John David Spencer, MD, and his dynamic team in the Spencer Lab.
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Bagaitkar Lab
The Bagaitkar Lab studies the complex interactions between innate immune cells, epithelial cells, and microbial colonizers at the oral mucosal barrier.
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Chisolm Lab Staff
Learn more about Deena Chisolm, PhD, and her dynamic team in the Chisolm Lab.