The Institute for Genomic Medicine (IGM) performs and analyzes integrated clinical genomic, molecular, microarray, FISH, and cytogenetic analyses to diagnose a broad range of inherited diseases and cancer. The Laboratory also serves as a centralized clinical testing laboratory for the Children’s Oncology Group leukemia, Wilms tumor, medulloblastoma, and rhabdomyosarcoma studies. IGM collaborates with researchers and pathologists to discover and translate new molecular markers into robust clinical assays. We emphasize collaborative interactions between clinicians, physician-scientists, and basic science investigators to quickly transition cutting edge research results into cutting edge diagnostics, using state-of-the-art technology platforms. With world-renowned experts at the helm, we are moving genome-based testing into the mainstream of pediatric diagnosis and treatment, making the results accessible and meaningful for physicians and families.