Hematology Flow Cytometry Lab

The Hematology Flow Cytometry Lab in the Department of Pathology and Laboratory Medicine at Nationwide Children’s Hospital provides clinical flow cytometry services, focusing on hematological malignancies such as lymphoma and leukemia.

Flow cytometry allows for rapid detection and characterization of microbial cells. Providers and researchers can use flow cytometry to analyze complex populations and evaluate peripheral blood, bone marrow, and other body fluids. Flow cytometry is used to identify and quantify immune cells and distinguish hematological malignancies.

What We Offer

The flow cytometry services at the Hematology Flow Cytometry Lab at Nationwide Children’s Hospital include both diagnosis of new or relapsed diseases and monitoring of treatment effect such as minimal residual disease (MRD) measurement. The lab also functions as a reference lab for outside institutes.

The Hematology Flow Cytometry Lab offers cutting-edge, 10-color assay for lymphoma/leukemia immunophenotyping. It is one of the few clinical flow cytometry labs certified by Children’s Oncology Group (COG) to run MRD analysis by flow cytometry with B lymphoblastic lymphoma/leukemia (B-ALL) using a COG standardized protocol.

In addition to lymphoma/leukemia immunophenotyping and B-ALL MRD, the Hematology Flow Cytometry Lab also offers:

  • EMA binding assay (or Band3 test) for diagnosis of hereditary spherocytosis or pyropoikilocytosis
  • CD34 stem cell count for stem cell transplant program
  • DNA ploidy analysis for neuroblastoma and B lymphoblastic lymphoma/leukemia
  • Diagnosis of immunological diseases including RORA, autoimmune lymphoproliferative disorders (ALPS panel), oxidase burst assay for chronic granulomatous disease, and leukocyte antigen detection for diagnosis of leukocyte adhesion deficiency

The Hematology Flow Cytometry Lab is committed to providing an accurate diagnosis as quickly as possible. Results are generally reported on the day we receive the specimen, and will be faxed or securely emailed as soon as they are signed out.

Dr. Huifei Liu, MD, PhD, is the Director of the Hematology Flow Cytometry Lab. She is board certified in Anatomic/Clinical Pathology and Hematopathology. She has over 20 years of experience with flow cytometry, including more than 8 years of experience in clinical flow cytometry.

Requisition Form

For Hematology Flow Cytometry Requisition, click here.

Contact Us

If you would like to learn more information about the Hematology Flow Cytometry Lab at Nationwide Children’s Hospital, or want to discuss specific flow cytometry services, please contact Laboratory Services at (877) 934-6575 or email Huifei Liu, MD, PhD, Director, Clinical Flow Cytometry Laboratory, at Huifei.Liu@NationwideChildrens.org.