Genetic and Genomic Medicine
Providing Care Through the Diagnosis and Treatment of Your Child's Genetic Disorder
Genetic and Genomic Medicine
Clinical (or Medical) Genetics is a medical specialty that uses genetic and genomic information to diagnose and treat hereditary disorders, maintaining and improving the health of individuals and families. Genetic Medicine encompasses medical genetics and the newer fields of personalized or precision medicine and gene therapies.
The mission of the Division of Genetic and Genomic Medicine at Nationwide Children’s Hospital is to improve the lives of individuals with genetic conditions by:
- Delivering compassionate, family-centered care for genetic and genomic diagnostic services
- Providing advanced therapies
- Supplying counseling, education and advocacy for our patients.
We care for individuals across all ages, from pre-conception and prenatal through childhood and well into adulthood. Our team provides:
- Diagnostic evaluations for patients with known or suspected genetic diseases,
- Genetic counseling for families and patients with genetic disorders or at risk for them, and
- Treatment for inborn errors of metabolism and multiple other genetic conditions.
New Patients
Now you can schedule appointments and second opinions online with a provider, time and location that is most convenient, or call (614) 722-6200.
Existing Patients
If your child is already a patient within Genetic and Genomic Medicine, you can schedule follow-up appointments right in MyChart or call (614) 722-6200.
Sign Up for MyChart
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Referring Physicians
We're one team. Our physician resources make referring your patients to our experts fast, seamless and ensures the highest quality of care.
View ResourcesCan't Find What You're Looking For?
If you are unable to schedule your next appointment through MyChart, fill out our online Request an Appointment form and a member of our scheduling team will be happy to assist you.
Services We Offer
Services we offer include:
- Genetic and Genomic Disorders
- Genetic Counseling Services
- Metabolic Consultation
- Hypermobility Disorders
What to Expect at Your First Visit
A genetics consult starts with a phone call from a genetic counseling assistant. The assistant will gather information about the reason for the visit, obtain a detailed history of any problems in the family (which is called a pedigree) and possibly request medical records from other providers or hospitals. Sometimes, the assistant may need sensitive information. During this first contact, if you do not want to come for a full visit or have concerns about sharing sensitive information, please let us know.
The first appointment will take about two hours. If the person who is referred is a child, they MUST come to the visit. Plan to arrive at least 30 minutes before your appointment time to allow ample time to get registered, complete forms and have measurements taken (height, weight, blood pressure).
You will meet with several healthcare providers at this visit. This will include a genetic counselor, a genetic nurse practitioner or genetics physician, and possibly a metabolic dietician.
A consult with genetics is more than having genetic testing. It includes a full assessment that consists of taking a detailed history, reviewing outside medical records and performing a complete exam. We will discuss possible conditions, provide genetic counseling and review what may be needed to establish a diagnosis. A decision about whether testing is required, and what kind of tests should be performed, will be discussed at the first visit.
In most cases, testing will not be done at that time. If testing is recommended, we will work with your insurance to get prior authorization and let you know when to return for testing.
A return visit with the nurse practitioner, geneticist or genetic counselor is often needed when test results are available. Our team will go over what the results mean and discuss any next steps. Genetic counseling will be provided at every step to ensure you understand what the results mean for the patient and the family. Finally, any needed additional tests will be ordered, and a care plan with specific treatments, if available, will be made.
Clinical services are supported partly by the Ohio Department of Health as a Regional Genetics Center of the State of Ohio, Region IV.
Leadership
Kandamurugu Manickam
Murugu Manickam, MD, MPH, FACMG, is Section Chief of Genetic and Genomic Medicine at Nationwide Children's Hospital.
Our Clinics
Genetics Clinic
Livingston Ambulatory Center
380 Butterfly Gardens Drive, 4th Floor
Columbus, OH 43215
(614) 722-3535
FAX (614) 722-3546
Metabolic Clinic
Livingston Ambulatory Center
380 Butterfly Gardens Drive, 4th Floor
Columbus, OH 43215
(614) 722-3543
FAX (614) 722-3546
Dublin Genetics Clinic
Dublin Medical Office Building
5665 Venture Drive
Dublin, OH 43017
(614) 722-3535
FAX (614) 722-3546
Tuesdays all day
Westerville Genetics Clinic
Westerville Surgery Center
455 Executive Campus Drive
(614) 722-3535
FAX (614) 722-3546
Mondays 8:00am – 12:00pm
Outreach Clinics
Athens Outreach
278 W. Union Street
Athens, OH 45701
To schedule, call: (614) 592-4431
FAX (614) 594-9929
Held bimonthly on a Wednesday
St. Rita's Medical Center
730 W Market Street
Lima, OH 45801
To schedule, call: (614) 722-3535
Fax referral to: (614) 722-3546
Office Phone: (419) 226-9694 or (800) 742-3208
4th Wednesday of the month
Marietta Outreach
Marietta City Health Department
304 Putnam Street
Marietta, OH 45750
To schedule, call: (740) 373-0611
FAX (740) 376-2008
Held bimonthly on a Wednesday
Zanesville Outreach
Muskingham Valley Health Care
719 Adair Avenue
Zanesville, Ohio 43701
To schedule, call: (614) 722-3535
Fax referral to: (614) 722-3546
Held bimonthly on a Wednesday
Affiliated Specialty Clinics
22q Center
Nationwide Children’s Hospital
700 Children’s Drive
Columbus, OH 43205
(614) 722-6200
FAX (614) 722-4000
Office phone (614) 962-6373
187 W. Schrock Rd.
Westerville, OH 43081
(614) 722-6200
FAX (614) 722-4000
Office phone (614) 355-8080
Complex Epilepsy Clinic (Epilepsy Center)
Nationwide Children’s Hospital
700 Children’s Drive
Columbus, OH 43205
(614) 722-6200
FAX (614) 722-4000
Cleft Lip and Palate Center
Nationwide Children’s Hospital
700 Children's Drive
Suite T5E
Columbus, Ohio 43205
(614) 722-6200
FAX (614) 722-4000
Office phone (614) 962-6366
Tues. 12:30 pm – 5 pm
Cystic Fibrosis Clinic
Outpatient Care Center, 5th Floor
555 S. 18th Street
Columbus, OH 43205
Phone: (614) 722-4766
Fax: (614) 722-4755
Tues PM, Wed PM, and Thurs PM
Down Syndrome Clinic (Developmental and Behavioral Pediatrics)
Nationwide Children’s Hospital
700 Children’s Drive
Columbus, OH 43205
(614) 722-6200
FAX (614) 722-4000
Office phone (614) 722-4050
Muscular Dystrophy Association (MDA)/Spinal Muscular Atrophy (SMA) Clinic
Outpatient Care Center, 1st Floor
555 S. 18th Street
Columbus, OH 43205
(614) 722-6200
FAX (614) 722-4000
Office phone (614) 722-2203
Wednesdays
Myelomeningocele Clinic (Developmental and Behavioral Pediatrics)
Nationwide Children’s Hospital
700 Children’s Drive
Columbus, OH 43205
(614) 722-6200
FAX (614) 722-4000
Office phone (614) 722-4050
Friday AM
Prader-Willi Syndrome Clinic (Endocrinology)
Outpatient Care Center, 5th Floor
555 S. 18th Street
Columbus, OH 43205
(614) 722-6200
FAX (614) 722-4000
Office phone (614) 722-4425
2nd Friday of the month
Williams Syndrome Clinic (Developmental and Behavioral Pediatrics)
Nationwide Children’s Hospital
700 Children’s Drive
Columbus, OH 43205
(614) 722-6200
FAX (614) 722-4000
Office phone (614) 722-4050
2nd Tuesday of the month
Research
Our research partners include the Institute for Genomic Medicine, the Center for Gene Therapy, and the Center for Cardiovascular Research.
Conditions We Treat
- 22q Deletion Syndrome
- Achondroplasia
- Aneuploidy
- Aortopathy
- Arrhythmia
- Beckwith Wiedemann Syndrome
- Brain Malformations
- Cardiomyopathy
- CHARGE Syndrome
- Cleft Lip and Palate
- Congenital Heart Defects
- Craniosynostosis
- Down Syndrome
- Ehlers Danlos
- Family History of Genetic Disease
- Fetal Alcohol Spectrum
- Fragile X Syndrome
- Galactosemia
- Hunter Syndrome
- Hurler Syndrome
- Hypophosphatasia
- Kabuki Syndrome
- Krabbe Disease
- Limb Differences
- Loeys Dietz Syndrome
- Marfan Syndrome
- MCAD Deficiency
- Metaphyseal Chondrodysplasia
- Mitochondrial Disease
- Muscular Dystrophy
- Neurofibromatosis
- Newborn Screen Abnormal Test
- Noonan Syndrome
- Organic Acidemias
- Osteogenesis Imperfecta
- Phenylketonuria
- Pompe Disease
- Prader Willi Syndrome
- Russell-Silver Syndrome
- Sanfilippo Syndrome
- Sotos Syndrome
- Spina Bifida and Myelomeningocele
- Stickler Syndrome
- Turner Syndrome
- Urea Cycle Disorders
- VATER VACTERL
- Williams Syndrome
Medical Genetics and Combined Pediatrics-Genetics Residencies
We currently offer a two-year Medical Genetics and four-year combined Pediatrics/Medical Genetics residency program at our institution.