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Theisen Lab
Under the direction of Emily Theisen, PhD, the Theisen Lab aims to increase the clinical impact of epigenetic targeted therapies for children with cancer.
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New National Study Emphasizes Need for Tree House Safety Standards
Although building and playing in tree houses is widely considered a rite of passage for children, it can unfortunately lead to serious injury. A recent study conducted by the Center for Injury Research and Policy of The Research Institute at Nationwide Children’s Hospital found that an
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Cribs, Playpens and Bassinets
Parents and caregivers rely on cribs to protect children while they sleep. However, more than 9,500 injuries related to cribs, playpens and bassinets are seen in U.S. emergency departments each year.
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Human MicroRNA Inhibits Expression of Pathogenic Gene Underlying Facioscapulohumeral Muscular Dystrophy
Facioscapulohumeral muscular dystrophy (FSHD) is caused by aberrant expression of the DUX4 gene in skeletal muscles. Researchers at Nationwide Children’s Hospital have recently demonstrated that an endogenous human microRNA, miR-675, inhibits DUX4 expression and protects muscles from DUX4-mediated cell death in a mouse model when administered via gene therapy. They also showed that the small molecule-based treatments that upregulate miR-675 inhibited DUX4 mRNA and DUX4-associated biomarkers in myotubes derived from patients with FSHD.
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Nationwide Children’s Hospital Selected as Clinical Coordinating Center in Large National Clinical Trial Sponsored by National Heart Lung and Blood Institute (NHLBI)
The National Heart Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH) has announced that Nationwide Children’s Hospital has been selected for funding as the Clinical Coordinating Center for the multicenter randomized trial: “Percutaneous intervention versus observational trial of arterial ductus in lower gestational age infants (PIVOTAL)”.
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Media Advisory: Hyundai Hope On Wheels To Award $250,000 Research Grant To Nationwide Children's Hospital In Honor Of National Childhood Cancer Awareness Month
On Thursday, September 28, 2017, Hyundai Hope On Wheels® will present Nationwide Children's Hospital with a $250,000 Hyundai Scholar Hope Grant. The grant funds will support the research of Timothy Cripe, MD, PhD, principal investigator and division chief of Hematology/Oncology and BMT. Dr.
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Stanton Lab
Under the direction of Benjamin Stanton, PhD, the Systems Epigenetics Group is a highly collaborative group, focusing on pediatric cancer epigenetics and genomics.
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PIVOTAL Network
The PIVOTAL Network is a group of healthcare providers, institutions, and researchers working in collaboration to determine the best approach to treat preterm infants diagnosed with patent ductus arteriosus, commonly referred to as a PDA.
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New Study Finds Alarming 15-fold Increase in Inflatable Bouncer-Related Injuries Among Children
A new study by researchers at the Center for Injury Research and Policy of The Research Institute at Nationwide Children’s Hospital examined pediatric injuries associated with inflatable bouncers, such as bounce houses and moonwalks.
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National Study Finds Rising Rate of Marijuana Exposure Among Children 5 Years Old and Younger
Debates about legalizing marijuana have focused on crime rates, economic benefits, and health effects among adults. But a study published today from researchers at Nationwide Children’s Hospital shows that the risk to young children of swallowing, breathing in or otherwise being exposed to