Nationwide Children's Research News

Dec 06, 2005

Unique Collaboration Formed to Enhance Pediatric Cancer Research

Today, Columbus Childrens Hospital, Cincinnati Childrens Hospital Medical Center and The Ohio State University Comprehensive Cancer Center have signed a collaborative agreement to broaden the study of childhood cancer and accelerate the transfer of key research findings to the clinical setting.

Aug 23, 2005

Genome Sequence for Haemophilus Influenzae Completed by Researchers at Columbus Children's Hospital

Haemophilus influenzae is a common cause of otitis media (ear infections) in children and is the number one reason young children are seen by pediatricians.

Jan 01, 0001

4-Year Study Finds No Correlation Between Head Impacts and Cognitive Outcomes in Youth Tackle Football Players

Dr. Sean Rose and colleagues collaborated with MORE Foundation, the Complex Concussion Clinic at Nationwide Children's, and other researchers to prospectively follow youth tackle football players in real time across four seasons, which can account for confounding factors. The study, recently published in JAMA Network Open, was conducted from July 2016 through January 2020, and enrolled players from four football teams. A total of 70 male players, 9-12 years of age, who were in 5th and 6th grade, volunteered to participate, with 18 completing all four years of the study.

Jan 01, 0001

Investigators Develop Technique to Effectively Edit NK Cells to Target Specific Cancer Cells

Originally, NK cells seemed promising for a natural therapy to fight cancer due to their innate ability to recognize any cells expressing stress or signs of infection. But investigators quickly realized they faced three key challenges: first, it was difficult to grow a large enough number of NK cells in the lab to offer useful infusions at a reasonable cost; second, an ideal universal donor solution was needed to make NK cell products faster, more reliably and with off-the-shelf availability; and third, NK cells were resistant to genetic modifications that might help them better target specific types of cancer cells. Nationwide Children’s Hospital investigators and their collaborators painstakingly solved the first two problems over the past decade. Now, they’ve conquered the third.