Nationwide Childrens Hospital Designated Translational Research Center in CF Foundations National Clinical Trials Network

September 28, 2009

Nationwide Childrens Hospital has been selected to serve as one of 13 special translational research centers in a network of 77 clinical trial sites that are part of the Therapeutics Development Network (TDN) of the Cystic Fibrosis Foundation.

The translational research centers will lead the newest Phase I clinical trials and provide scientific direction to the entire network.  This new designation will allow Nationwide Childrens to be a leader in cutting-edge research combating the life-shortening, genetic disease cystic fibrosis.

As a translational research center for the Cystic Fibrosis Foundations Therapeutics Development Network, our patients will have access to some of the latest advances in cystic fibrosis treatment and our faculty will be some of the first to generate new research projects, said Karen McCoy, MD, director of the hospitals Cystic Fibrosis Care Center and chief of Pulmonary Medicine at Nationwide Childrens.  McCoy is also a faculty member of The Ohio State University College of Medicine.

The clinical trials network is responsible for facilitating safe, rapid and coordinated evaluation of new treatments for cystic fibrosis.  In order to meet the growing need for study participants and expanded research programs, the network was expanded this year from 18 to 77 sites, including the 13 translational research centers.

The Section of Pulmonary Medicine at Nationwide Childrens participated in its first cystic fibrosis clinical trial in 1992, the third-ever cystic fibrosis clinical trial world-wide, and has since taken part in more than 50 clinical trials for cystic fibrosis. The hospital has been a CFF TDN member since 2002.

Nationwide Childrens selection as a cystic fibrosis translational research center reflects our institutions outstanding ability to unite progressive clinical care with innovative scientific research, said John Barnard, MD, president of The Research Institute at Nationwide Childrens and a faculty member of The Ohio State University College of Medicine.  We are extremely proud of our state-of-the-art cystic fibrosis program.

Added Preston W. Campbell, III, Executive Vice President of Medical Affairs for the Cystic Fibrosis Foundation: We congratulate Nationwide Childrens on joining a network of premier clinical trial facilities. These centers will help CF drugs move more swiftly from the research and testing stage into the hands of patients who need them.

Since its inception in 1998, the clinical trials network has established processes and central reading centers for microbiology, inflammatory markers, nasal potential difference measurement, chest imaging and infant pulmonary function testing. These standard operating procedures are available to all cystic fibrosis researchers worldwide and have resulted in improvements in care and prolonged survival of cystic fibrosis patients.

 The outlook for this devastating disease is better than ever. The median age of survival for cystic fibrosis patients has more than doubled in the past 25 yerars. The Cystic Fibrosis Foundation has been a visionary in its diversified to fighting CF and attacking the disease from every angle, said McCoy.

About Nationwide Children's Hospital

Named to the Top 10 Honor Roll on U.S. News & World Report’s 2017-18 list of “America’s Best Children’s Hospitals,” Nationwide Children’s Hospital is one of America’s largest not-for-profit freestanding pediatric healthcare systems providing wellness, preventive, diagnostic, treatment and rehabilitative care for infants, children and adolescents, as well as adult patients with congenital disease. Nationwide Children’s has a staff of nearly 13,000 providing state-of-the-art pediatric care during more than 1.4 million patient visits annually. As home to the Department of Pediatrics of The Ohio State University College of Medicine, Nationwide Children’s physicians train the next generation of pediatricians and pediatric specialists. The Research Institute at Nationwide Children’s Hospital is one of the Top 10 National Institutes of Health-funded freestanding pediatric research facilities. More information is available at NationwideChildrens.org.