Eosinophilic Esophagitis (EoE) Clinic

The Eosinophilic Esophagitis (EoE) Clinic at Nationwide Children’s Hospital coordinates care for children and adolescents by pediatric specialists within Gastroenterology and Allergy/Immunology. In addition, patients can participate in ongoing research studies to improve evaluation and treatment of EoE.

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About the Eosinophilic Esophagitis (EoE) Clinic

Eosinophilic esophagitis (EoE) is a condition caused by inflammation of the esophagus (swallowing tube) between your mouth and stomach. It is often caused by allergies. Symptoms of EoE may include difficulty swallowing, pain, nausea, regurgitation and vomiting. At Nationwide Children’s, specialists within Gastroenterology and Allergy/Immunology are skilled in distinguishing EoE from other disorders, such as gastroesophageal reflux (GER), that may cause similar symptoms. As a team, these specialists provide guidance for families to make informed decisions about the care of their child. 

Meet our Team

The EoE team at Nationwide Children’s specializes in the causes and therapies of allergic inflammatory conditions of the esophagus. Elizabeth Erwin, MD, researches and practices in the area of allergy and immunology with a focus on understanding allergies in patients with EoE. Dr. Erwin has published on the topic of eosinophilic esophagitis and brings her expertise, along with that of pediatric gastroenterologists John Russo, MD, and Rajitha Venkatesh, MD, to services provided within the Division of Gastroenterology, Hepatology and Nutrition.

Treatment of EoE

EoE is often a chronic or recurrent disease. Treatment options are different depending on the child’s symptoms and specific allergies. In some cases, medication may be used to relieve symptoms and then stopped if no longer necessary. Other treatment options, such as specific food avoidance, may be lifelong changes in order to manage EoE. Sometimes endoscopies are recommended to determine whether a treatment options has worked.

Current treatments include: 

  • Medications
  • Specific dietary avoidance – avoiding certain foods that are positive by allergy testing 
  • “Six-food” elimination diet – removing all of the most commonly allergenic food groups (milk, wheat, egg, soy, peanut, tree nuts, and seafood) and then slowly bringing foods back into the diet to determine which foods may be triggering EoE
  • Complete elimination diet – a formula-only diet

Meet Our Patients

DeMari's Story

Read DeMari's Story

Name: DeMari M.
Condition(s): Eosinophilic Esophagitis
Age Today: 9 Years

When DeMari was a baby she had constant trouble swallowing and would choke and gag on liquids and solids. It got to the point that she wouldn't eat. After multiple tests her family was told that DeMari had Eosinophilic Esophagitis.

Madeleine S

Read Madeleine's Story

Name: Madeleine S.
Condition(s): Allergic Inflammation, Eosinophilic Esophagitis
Age Today: 12 Years

Madeleine was born 10 weeks prematurely. The vomiting began as soon as she started eating, but she remained happy and growing. When she was 8 months old, the vomiting became worse. In fact, she started to avoid movement because it made her throw up.

Resources for Families

Learn more about EoE through GIKids, the patient outreach and education effort of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN).

What Research Is Being Done on EOE?

Nationwide Children’s is taking a closer look at causes and therapies of allergic inflammatory conditions of the esophagus. Elizabeth Erwin, MD, researches and practices in the area of allergy and immunology with a focus on understanding allergies in patients with EoE. Dr. Erwin has published on the topic of eosinophilic esophagitis and brings her expertise, along with that of pediatric gastroenterologist John Russo, MD, and to services provided within the Division of Gastroenterology, Hepatology and Nutrition.

Predicting Esophageal Eosinophilia Using Serum IgE Antibody Results

Researchers can predict the presence of esophageal eosinophils — even in children with nonspecific gastrointestinal symptoms — using food-specific IgE test results and a simple new algorithm.