The Great Lakes Emergency Medical Services for Children Research Network (GLEMSCRN) is part of the Pediatric Emergency Care Applied Research Network (PECARN). PECARN is the first federally-funded multi-institutional network for research in pediatric emergency medicine in the United States. The goal of this network is to conduct meaningful and rigorous multi-institutional research into the prevention and management of acute illnesses and injuries in children and youth across the continuum of emergency medicine health care.

Institutions: Nationwide Children’s Hospital, University of Michigan, UPMC Children's Hospital of Pittsburgh
Principal Investigator: Rachel Stanley, MD, MHSA

Goals and Objectives

The overall goal of this project is to enhance emergency medical services-related research and its subsequent impact by developing and conducting research and disseminating research findings. To accomplish this goal we will complete the following objectives:

  1. Support a research infrastructure to conduct important pediatric emergency medicine research.
  2. Support a research process to develop projects, attain funding and conduct rigorous mult-site clinical studies in pediatric emergency medicine.
  3. Facilitate dissemination and translation of research results to pediatric emergency medicine practices.
  4. Foster collaboration between academic and treatment communities.

Hospital Emergency Department Affiliates (HEDAs)

  • Nationwide Children’s Hospital 
  • University of Michigan (Ann Arbor, MI)
  • University of Pittsburgh Medical Center, Children’s Hospital of Pittsburgh (Pittsburgh, PA)

Great Lakes EMS-C Node of the Pediatric Emergency Care Applied Research Network (PECARN)

Ambulance crews and emergency rooms in the Midwest are able to give kids better, more coordinated and more advanced emergency medical care, thanks to a coalition of Midwestern hospitals.

GLEMSCRN is one of only six nodes nationwide funded for research, training and education in pediatric emergency medicine. The network includes Nationwide Children’s Hospital (Columbus, OH), Children's Hospital of Michigan (Detroit, MI) and University of Michigan (Ann Arbor, MI).

Network members are dedicated to improving health care for ill and injured children through research and collaboration:

  • Performing meaningful and rigorous research to determine optimal strategies to promote health in the preventive, prehospital and hospital phases of care; and
  • Collaborating with EMS agencies and community groups to address emergency care needs; and collaborating with other research nodes to build rigorous and widely applicable research.

The GLEMSCRN project is led by Rachel Stanley, MD, MHSA, Division Chief of Emergency Medicine and Associate Professor of Pediatrics at The Ohio State University. She says the network focuses on a broad range of children's emergency medical issues, including pre-hospital care, injuries, violence, acute infectious diseases, access to emergency care and medical training.

Since receiving funding over 15 years ago, the network has developed an infrastructure to conduct multi-site research in the Great Lakes Region. The network focuses on research and education for physicians and emergency responders in the specific needs of children. "Compared with adults, medical emergencies in kids are rare, so much more cooperation is needed to gather data and prove the effectiveness of treatment," says Stanley.

The grant was given under the federal Emergency Medical Services for Children program, administered by the Health Services Research Administration's Maternal and Child Health Bureau.

The Great Lakes EMSC Research Network is one of six research networks funded nationwide. The other five networks funded are the Hospitals of the Midwest Emergency Research Node (HOMERUN) centered at Cincinnati Children’s Hospital Medical Center; the Pediatric Emergency Medicine Northeast, West & South (PEM-NEWS), centered at Columbia University in New York City; the Pediatric Research in Injures and Medical Emergencies (PRIME), centered at the University of California, Davis Medical Center ; the Pittsburgh, Rhode Island, Delaware Network (PRIDENET), centered at Children’s Hospital of Pittsburgh; and the Washington, Boston, Chicago Applied Research Node (WBCARN) centered at Children's National Medical Center in Washington, D.C.

EMSC is a national initiative designed to reduce disability and death in children and young people from severe illness and injury. It focuses on prevention, and on ensuring that all ill or injured children receive state-of-the-art emergency medical care from emergency medical technicians and paramedics, emergency department personnel, and rehabilitation specialists.

Principal Investigator

Rachel Stanley, MD, MHSA
Nationwide Children's Hospital
Emergency Medicine Department
700 Children's Drive
Columbus, OH 43205
Phone: 614-722-4385
Fax: 614-722-4380

Nodal Administrators

Jessica Saunders, MACPR 
Nationwide Children’s Hospital 
Emergency Medicine Department 
700 Children’s Drive 
Columbus, OH 43205 
Phone: 614-722-4385 
Fax: 614-722-4380 

Sherry Goldfarb, MPH
University of Michigan
Emergency Medicine Research
24 Frank Lloyd Wright Drive, Suite H-3200
P.O. Box 443
Ann Arbor, MI 48106
Phone: 734-763-7488
Fax: 734-936-2706

Hospital Emergency Department Affiliate Investigators

Alexander Rogers, MD
University of Michigan
Emergency Medicine Research
24 Frank Lloyd Wright Drive, Suite H-3200
P.O. Box 443
Ann Arbor, MI 48106
Phone: 734-763-4964
Fax: 734-936-2706

Daniel M. Cohen, MD

Nationwide Children's Hospital
Section of Emergency Medicine
700 Children's Drive, ED 213
Columbus, OH 43205
Phone: 614-722-4385

Robert Hickey, MD
UPMC Children’s Hospital of Pittsburgh 
Pediatric Emergency Medicine 
4401 Penn Ave. 
Pittsburgh, PA 15224 
Phone: 412-692-7692 

Nationwide Children's Hospital (The Ohio State University) - Columbus, OH

Rachel Stanley, MD, MHSA - Principal Investigator
Associate Professor of Pediatrics, The Ohio State University
Division Chief, Emergency Medicine

Daniel M. Cohen, MD - Co-Investigator
Associate Professor of Pediatrics, The Ohio State University
Research Director, Pediatric Emergency Medicine

Nationwide Children's Hospital is ranked as one of the nation’s ten largest freestanding children’s hospitals and pediatric research centers in the country. Strategically, the hospital is dedicated to providing the highest quality of care to sick children regardless of ability to pay. It aims to: enhance all facets of patients' experience through family-centered care, discover new treatments through innovative research and increase performance and capacity to meet patient/community needs.

University of Michigan Health System - Ann Arbor, MI

Alexander Rogers, MD - Co-Investigator
Clinical Assistant Professor, Emergency Medicine
Department of Emergency Medicine

The University of Michigan Health System is at the forefront of patient care, medical education, and scientific and clinical research. As part of the University of Michigan Health System, C. S. Mott Children's Hospital integrates clinical care, education, advocacy, and research to advance the health status of children, their families and communities statewide. Mott maintains a leadership role in providing a full range of state-of-the-art, family-centered children's care and specialty services.

UPMC Children’s Hospital of Pittsburgh - Pittsburgh, PA

Robert Hickey, MD - Co-Investigator 
Professor of Pediatrics, Pediatric Emergency Medicine, University of Pittsburgh 
Director of Research, Pediatric Emergency Medicine

The UPMC Children’s Hospital of Pittsburgh’s Division of Pediatric Emergency Medicine is a very robust infrastructure that treats nearly 70,000 children in the Emergency Department every year. Their mission of the staff of the Emergency Department is to deliver the highest quality care to children with acute illnesses and injuries, as well as provide excellence in service to our patients and referring physicians.

News - Great Lakes Node of PECARN

April 15, 2015
Teen Suicide - PediaCast 315

This PediaCast discusses the scope of the problem of teen suicide, risk factors, warning signs, prevention strategies, treatment options, long-term outlook for suicidal teens and ongoing research projects aimed at identifying at-risk youth and getting them plugged-in to the help they need. Drs. David Axelson, Jeff Bridge and Dan Cohen are guests.

Click here to listen to the PediaCast on teen suicide.

December 17, 2014
Infant Fever - PediaCast 305

Dr. Daniel Cohen and Dr. Prashant Majahan join Dr. Michael Patrick in the PediaCast studio to discuss traditional and emerging technologies in the evaluation and management of young infants with fever.

Click here to listen to the PediaCast on infant fever.

May 21, 2014
Pediatric Seizure Study Completed: What We Learned

University of Michigan physicians and researchers joined a partnership of 14 children’s hospitals and universities across the country to find out which of two commonly prescribed medications is best for treating seizures in children in the emergency room. The Pediatric Seizure Study started enrolling patients here at the University of Michigan in 2008 and stopped enrolling July 2011. Analysis of the data collected show that there is no significant difference in the effectiveness and safety of treating seizures between lorazepam and diazepam.

  • Both drugs are about 72% effective in stopping seizures.
  • Both drugs had approximately the same rates of serious respiratory depression, about 17%.
  • There was no difference between the two drugs in stopping seizures with just one dose.
  • There was no difference between the two drugs in the number of children whose seizures returned after successful treatment.
  • Aspiration risk was very low (~1%) in both groups.

In conclusion, both lorazepam and diazepam continue to be safe for use in children for the treatment of seizures; and neither one is better than the other one.

Thank you to the community for your invaluable contribution through your understanding, feedback, questions and comments. We encourage parents and families to call 1-866-377-8557 for more information about results from the study.

The Pediatric Seizure Study is sponsored by the National Institute of Child Health and Human Development (NIH), an agency of the federal government.

This project is supported in part by the Health Resources and Services Administration (HRSA), Maternal and Child Health Bureau (MCHB), Emergency Medical Services for Children (EMSC) Network Development Demonstration Program under cooperative agreement number U03MC00008 for $3,000,000, and is partially support by MCHB cooperative agreements: U03MC00001, U03MC00003, U03MC00006, U03MC00007, U03MC22684 U03MC22685. This information or content and conclusions are those of the author and should not be construed as the official position or policy of, nor should any endorsements be inferred by HRSA, HHS or the U.S. Government.