Nationwide Children's News Releases
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Jan 01, 0001
Investigators Develop Technique to Effectively Edit NK Cells to Target Specific Cancer Cells
Originally, NK cells seemed promising for a natural therapy to fight cancer due to their innate ability to recognize any cells expressing stress or signs of infection. But investigators quickly realized they faced three key challenges: first, it was difficult to grow a large enough number of NK cells in the lab to offer useful infusions at a reasonable cost; second, an ideal universal donor solution was needed to make NK cell products faster, more reliably and with off-the-shelf availability; and third, NK cells were resistant to genetic modifications that might help them better target specific types of cancer cells. Nationwide Children’s Hospital investigators and their collaborators painstakingly solved the first two problems over the past decade. Now, they’ve conquered the third.
Jan 01, 0001
A Single-Dose Cancer Immunotherapy via Gene Transfer
Researchers at Nationwide Children’s Hospital report proof-of-principle results for a new gene therapy cancer treatment. The off-the-shelf, single-dose immunotherapy serves as an alternative to CAR-T therapy and can be engineered to be on-demand.
Jan 01, 0001
Nationwide Children’s Hospital and Big Lots Announce 2022 Recipient of Big Lots Behavioral Health Scholarship
Christy Chacko, a graduate student at the University of Southern California, is the 2022 recipient of the Big Lots Behavioral Health Scholarship—a scholarship made possible by Nationwide Children’s Hospital and Big Lots, an Ohio-based home discount retailer.