Post-Thrombotic Syndrome (PTS)

Helping Hand Logo

Post-Thrombotic Syndrome (post throhm BAH tik sinn drohm) or PTS can occur when there are changes in a blood vessel after a blood clot is formed.

PTS develops in about 25% of children who have a blood clot called Deep Vein Thrombosis (DVT). People with a more extensive DVT are more at risk for developing PTS.

Signs and Symptoms

Early signs of Post-Thrombotic Syndrome (PTS):

  • Swelling in an arm or leg
  • Pain in the arm or leg
  • Changes in skin color
  • Dilated blood vessels in the affected arm or leg 

A Later Sign Is:

  • Skin ulcers (these can develop, but are rare)

If you notice any of these symptoms or have concerns, call your child’s doctor right away.


There is no specific test to diagnose PTS. An ultrasound can look at blood flow. Your child will need to be evaluated by a doctor.


There is no known cure for PTS, but it can be managed with:

  • Compression stockings
  • Elevating the affected arm or leg
  • Regular diet and exercise

Expect to have regular follow-up appointments with your child's doctor.

Post-Thrombotic Syndrome (PTS) (PDF)

HH-I-419 5/17 Copyright 2017, Nationwide Children's Hospital