Kandamurugu Manickam, MD :: Nationwide Children’s Hospital, Columbus, Ohio

Kandamurugu Manickam, MD

Kandamurugu Manickam, MD

Contact Information

Molecular & Human Genetics
700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 722-3535
FX: (614) 722-3546


Kandamurugu Manickam, MD, is a clinical geneticist at Nationwide Children’s Hospital with a joint appointment in the James Cancer Center at The Ohio State University Medical Center and an Assistant Professor of Clinical Pediatrics at The Ohio State University College of Medicine. Dr. Manickam received his medical degree from the Royal College of Surgeons in Ireland, completed a residency in internal medicine-pediatrics at MetroHealth Medical Center in Cleveland and completed a fellowship in clinical genetics at the University of North Carolina at Chapel Hill. He is board certified in internal medicine and board-eligible in pediatrics and clinical genetics. He sees both children and adults with genetic disorders. His clinical interests are rare disease as well as common disease genetics and preventative care for both of these areas. In addition he works on the transition of pediatric genetic patients to adult genetics care to follow the natural history of rare conditions. Other areas of interest are the societal and ethical considerations of genetic testing especially for common diseases and is getting a Masters in Public Health in the field of Healthcare leadership and policy. He has been an invited lecturer and moderator at national meetings on the ethical and social implications of genetic research. His research focus is on common disease genetics and health care policy as it relates to genetics. In addition he is helping design a new master’s level program at The Ohio State University to train genetic counselors.


  • Male

Languages Spoken:

  • English

Education and Training

Medical School

  • The Royal College of Surgeons in Ireland
    Date Completed: 05/31/2002


  • Metro Health Medical Center
    Date Completed: 06/30/2006


  • University of North Carolina at Chapel Hill Hospital
    Date Completed: 07/31/2008


  • Pediatrics


  • Genetic and Genomic Medicine


  • Clinical Genetics
  • Internal Medicine

Date of Appointment at Nationwide Children’s Hospital:

  • 08/01/2017


  • Manickam,Kandamurugu; Donoghue,Daniel,J; Meyer,April,N; Snyder,Pamela,J; Prior,Thomas,W. 2014. Suppression of severe achondroplasia with developmental delay and acanthosis nigricans by the p.Thr651Pro mutation.  American journal of medical genetics. Part A. Vol. 164, no. 1. (January): 243-250.
  • Mullegama,Sureni,V; Rosenfeld,Jill,A; Orellana,Carmen; van Bon,Bregje,WM; Halbach,Sara; Repnikova,Elena,A; Brick,Lauren; Li,Chumei; Dupuis,Lucie; Rosello,Monica; Aradhya,Swaroop; Stavropoulos,D,James; Manickam,Kandamurugu; Mitchell,Elyse; Hodge,Jennelle,C; Talkowski,Michael,E; Gusella,James,F; Keller,Kory; Zonana,Jonathan; Schwartz,Stuart; Pyatt,Robert,E; Waggoner,Darrel,J; Shaffer,Lisa,G; Lin,Angela,E; de Vries,Bert,BA; Mendoza-Londono,Roberto; Elsea,Sarah,H. 2014. Reciprocal deletion and duplication at 2q23.1 indicates a role for MBD5 in autism spectrum disorder.  European journal of human genetics. Vol. 22, no. 1. (January): 57-63.
  • Sweet K, Gordon ES, Sturm AC, Schmidlen TJ, Manickam K, et al. 2014. Design and Implementation of a Randomized Controlled Trial of Genomic Counseling for Patients with Chronic Disease.  Journal of Personalized Medicine. Vol. 1, no. January: 1-19.
  • Shuldiner,A,R; RELLING,M,V; Peterson,J,F; Hicks,J,K; Freimuth,R,R; Sadee,W; Pereira,N,L; Roden,D,M; Johnson,J,A; Klein,T,E. 2013. The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real-World Implementation.  CLINICAL PHARMACOLOGY & THERAPEUTICS. Vol. 94, no. 2. (August): 207-210.
  • Sturm,Amy,Curry; Sweet,Kevin; Manickam,Kandamurugu. 2013. Implementation of a clinical research pharmacogenomics program at an academic medical center: role of the genetics healthcare professional.  PHARMACOGENOMICS. Vol. 14, no. 7. (May): 703-706.
  • Manickam,K; Allain,D; Grover,M. 2012. Physical health and well-being of adults with Down syndrome.  JOURNAL OF INTELLECTUAL DISABILITY RESEARCH. Vol. 56, no. 7-8. (July): 760-760.
  • Sturm,Amy,C; Manickam,Kandamurugu. 2012. Direct-to-Consumer Personal Genomic Testing: A Case Study and Practical Recommendations for "Genomic Counseling".  JOURNAL OF GENETIC COUNSELING. Vol. 21, no. 3. (June): 402-412.
  • Kitzmiller,Joseph,P; Embi,Peter,J; Manickam,Kandamurugu; Sweet,Kevin,M; Phelps,Mitch,A; Jackson,Rebecca,D; Marsh,Clay,B; Sadee,Wolfgang. 2012. Program in Pharmacogenomics at the Ohio State University Medical Center.  PHARMACOGENOMICS. Vol. 13, no. 7. (May): 751-756.
  • Rosenfeld JA; Amrom D; Andermann E; Andermann F; Veilleux M; Curry C; Fisher J; Deputy S; Aylsworth AS; Powell CM; Manickam K; Heese B; Maisenbacher M; Stevens C; Ellison JW; Upton S; Moeschler J; Torres-Martinez W; Stevens A; Marion R; Pereira EM; Babcock M; Morrow B; Sahoo T; Lamb AN; Ballif BC; Paciorkowski AR; Shaffer LG. 2012. Genotype-phenotype correlation in interstitial 6q deletions: a report of 12 new cases.  Neurogenetics. Vol. 13, no. 1. (February): e31.
  • Morton,Sara,Anne (Adams); Coppinger,Justine; Ballif,Blake,C; Shaffer,Lisa,G; Ellison,Jay,W; Saitta,Sulagna,C; Stroud,Tracy; Manickam,Kandamurugu; Fan,Zheng. 2011. Regarding cancer predisposition detected by CHG arrays Response.  GENETICS IN MEDICINE. Vol. 13, no. 11. (November): 982-983.
  • Cottrell,Catherine,E; Prior,Thomas,W; Pyatt,Robert; Astbury,Caroline; Reshmi,Shalini; Bartholomew,Dennis; Atkin,Joan; Manickam,Kandamurugu; Thrush,Devon,Lamb; Pastore,Matthew; Mendell,Jerry; Tsao,Chang-Yong; Al-Dahhak,Roula; Newmeyer,Amy; Gastier-Foster,Julie,M. 2010. Unexpected Detection of Dystrophin Gene Deletions by Array Comparative Genomic Hybridization.  AMERICAN JOURNAL OF MEDICAL GENETICS PART A. Vol. 152A, no. 9. (September): 2301-2307.
  • McBride,Kim,L; Varga,Elizabeth,A; Pastore,Matthew,T; Prior,Thomas,W; Manickam,Kandamurugu; Atkin,Joan,F; Herman,Gail,E. 2010. Confirmation Study of PTEN Mutations Among Individuals with Autism or Developmental Delays/Mental Retardation and Macrocephaly.  AUTISM RESEARCH. Vol. 3, no. 3. (June): 137-141.
  • Facio,Flavia,M; Feero,W,Gregory; Linn,Amy; Oden,Neal; Manickam,Kandamurugu; Biesecker,Leslie,G. 2010. Validation of My Family Health Portrait for six common heritable conditions.  GENETICS IN MEDICINE. Vol. 12, no. 6. (June): 370-375.
  • Adams SA, Coppinger J, Saitta SC, Stroud T, Kandamurugu M, Fan Z, Ballif BC, Shaffer LG, Bejjani BA. 2009. Impact of genotype-first diagnosis: the detection of microdeletion and microduplication syndromes with cancer predisposition by aCGH.  Genetics in Medicine. Vol. 5, no. 11. (January): 314-322.
Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000